Chemokine receptor CXCR4-beta1 integrin axis mediates tumorigenesis of osteosarcoma HOS cells.

scientific article published on February 2005

Chemokine receptor CXCR4-beta1 integrin axis mediates tumorigenesis of osteosarcoma HOS cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1139/O04-106
P698PubMed publication ID15746965
P5875ResearchGate publication ID7987152

P50authorSubrata ChakrabartiQ52983647
Mircea LeabuQ57575274
P2093author name stringTamas Oravecz
Bosco M C Chan
Shashi Uniyal
Kohei Miura
Vincent L Morris
P2860cites workIn vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cellsQ41690709
Subsecond induction of alpha4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditionsQ41891156
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Diverse transcriptional response of CD4+ T cells to stromal cell-derived factor SDF-1: cell survival promotion and priming effects of SDF-1 on CD4+ T cellsQ43729104
Mechanism of beta 1-integrin-mediated hepatoma cell growth involves p27 and S-phase kinase-associated protein 2.Q44527573
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Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient miceQ24681021
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The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tractQ28504884
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Taking cell-matrix adhesions to the third dimensionQ29615214
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Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.Q36368653
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Modulation of in vivo migratory function of alpha 2 beta 1 integrin in mouse liverQ36926631
CD4-independent association between HIV-1 gp120 and CXCR4: functional chemokine receptors are expressed in human neuronsQ39066033
The alpha5beta1 integrin selectively enhances epidermal growth factor signaling to the phosphatidylinositol-3-kinase/Akt pathway in intestinal epithelial cellsQ40749861
The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow.Q40762163
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Specific residues within the alpha 2 integrin subunit cytoplasmic domain regulate migration and cell cycle progression via distinct MAPK pathwaysQ40797356
Over expression of integrin alpha 5 beta 1 in human hepatocellular carcinoma cell line suppresses cell proliferation in vitro and tumorigenicity in nude miceQ40869306
The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathwaysQ41012131
The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4.Q41101616
Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) geneQ41312923
P433issue1
P304page(s)36-48
P577publication date2005-02-01
P1433published inBiochemistry and Cell BiologyQ4914719
P1476titleChemokine receptor CXCR4-beta1 integrin axis mediates tumorigenesis of osteosarcoma HOS cells
P478volume83

Reverse relations

cites work (P2860)
Q33316250A complex pattern of chemokine receptor expression is seen in osteosarcoma
Q35794312AMD3100 reduces CXCR4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments
Q38764542Altered CXCL12 expression reveals a dual role of CXCR4 in osteosarcoma primary tumor growth and metastasis
Q40003696Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling
Q36737015Diffuse calcification of metastases after intensive multiagent chemotherapy in widespread osteosarcoma leading to death in a 18-year-old male: report of a case and literature review
Q27307103Expression of the chemokine receptor CXCR7 in CXCR4-expressing human 143B osteosarcoma cells enhances lung metastasis of intratibial xenografts in SCID mice
Q36916624Hitting Them Where They Live: Targeting the Glioblastoma Perivascular Stem Cell Niche
Q39398473Imaging the inhibition by anti-β1 integrin antibody of lung seeding of single osteosarcoma cells in live mice.
Q38626906Immuno-Oncology Integrative Networks: Elucidating the Influences of Osteosarcoma Phenotypes
Q36015267Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells
Q33530762Investigation of integrin expression on the surface of osteoblast-like cells by atomic force microscopy
Q35199223Knockdown of the β(1) integrin subunit reduces primary tumor growth and inhibits pancreatic cancer metastasis
Q35727350Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4.
Q39543648Stromal cell-derived factor-1/CXC receptor 4 and β1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells
Q36614617The alpha2beta1 integrin mediates the malignant phenotype on type I collagen in pancreatic cancer cell lines

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