Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials.

scientific article published on 7 October 2015

Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1078-0432.CCR-15-0321
P698PubMed publication ID26446943
P5875ResearchGate publication ID282669047

P50authorKeith FlahertyQ6384357
Dirk SchadendorfQ32649390
Axel HauschildQ32649861
Georgina V. LongQ42947998
Richard F. KeffordQ46460242
Patrick HwuQ89392895
Vicki GoodmanQ117251019
Jeffrey J LegosQ117251020
P2093author name stringRobert Gagnon
Anne-Marie Martin
Michelle Casey
Ademi Santiago-Walker
Anne O'Hagan
Jennifer Carver
Jolly Mazumdar
Patricia Haney
P2860cites workMutations of the BRAF gene in human cancerQ27860760
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)567-574
P577publication date2015-10-07
P1433published inClinical Cancer ResearchQ332253
P1476titleCorrelation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials.
P478volume22

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cites work (P2860)
Q91646745Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma
Q58113203Cell-free DNA in cancer: current insights
Q90645875Circulating Cell-Free miR-375 as Surrogate Marker of Tumor Burden in Merkel Cell Carcinoma
Q39534880Circulating Tumor DNA as an Early Indicator of Response to T-cell Transfer Immunotherapy in Metastatic Melanoma
Q26745985Circulating biomarkers to monitor cancer progression and treatment
Q52601844Circulating cell-free DNA for non-invasive cancer management.
Q89496328Circulating tumor DNA analysis in the era of precision oncology
Q58704645Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors
Q48522100Circulating tumor DNA predicts survival in patients with resected high risk stage II/III melanoma.
Q38780043Circulating tumor markers: harmonizing the yin and yang of CTCs and ctDNA for precision medicine.
Q57143867Clinical potential of circulating tumour DNA in patients receiving anticancer immunotherapy
Q49464812Clinical significance of BRAFV600E mutation in circulating tumor DNA in Chinese patients with melanoma
Q49112520Combination of dabrafenib plus trametinib for BRAF and MEK inhibitor pretreated patients with advanced BRAFV600-mutant melanoma: an open-label, single arm, dual-centre, phase 2 clinical trial.
Q100455159Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i
Q55186392Concerning the article by Louveau et al "Clinical value of early detection of circulating tumour DNA BRAFV600mut in patients with metastatic melanoma treated with a BRAF inhibitor".
Q92206685Considering adjuvant therapy for stage II melanoma
Q55536917Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients.
Q52658584Cutaneous melanoma: From pathogenesis to therapy (Review).
Q36378903Development and validation of an ultra-deep next-generation sequencing assay for testing of plasma cell-free DNA from patients with advanced cancer
Q64080463Development of Novel Mutation-Specific Droplet Digital PCR Assays Detecting TERT Promoter Mutations in Tumor and Plasma Samples
Q89749356EGFR T790M relative mutation purity predicts osimertinib treatment efficacy in non-small cell lung cancer patients
Q38661826Efficient treatment of a metastatic melanoma patient with a combination of BRAF and MEK inhibitors based on circulating tumor DNA analysis: a case report
Q58757488From validity to clinical utility: the influence of circulating tumor DNA on melanoma patient management in a real-world setting
Q47563363Incorporating Blood-based Liquid Biopsy Information into Cancer Staging: Time for a TNMB System?
Q48527971Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers
Q39149201Liquid biopsies come of age: towards implementation of circulating tumour DNA.
Q38700529Liquid biopsy utility for the surveillance of cutaneous malignant melanoma patients
Q57471881Locus-specific concordance of genomic alterations between tissue and plasma circulating tumor DNA (ctDNA) in metastatic melanoma
Q58781162MMP-9 as a Candidate Marker of Response to BRAF Inhibitors in Melanoma Patients With Mutation Detected in Circulating-Free DNA
Q47227422Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells
Q39208242Molecular genetic and immunotherapeutic targets in metastatic melanoma
Q47392574Molecular testing for BRAF mutations to inform melanoma treatment decisions: a move toward precision medicine
Q59799469Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients
Q38376723Multiplex KRASG12/G13 mutation testing of unamplified cell-free DNA from the plasma of patients with advanced cancers using droplet digital polymerase chain reaction
Q38376337Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers
Q90569462Nanotechnology Strategies for the Analysis of Circulating Tumor DNA: A Review
Q96953882Optimal treatment strategy for metastatic melanoma patients harboring BRAF-V600 mutations
Q58079189Phase 1 study of the combination of vemurafenib, carboplatin, and paclitaxel in patients With BRAF-mutated melanoma and other advanced malignancies
Q39292740Plasma Circulating Tumor DNA Levels for the Monitoring of Melanoma Patients: Landscape of Available Technologies and Clinical Applications.
Q93271158Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma
Q39408199Platelets, circulating tumor cells, and the circulome.
Q92297174Pre-operative ctDNA predicts survival in high-risk stage III cutaneous melanoma patients
Q36815383Quantitative assessment of BRAF V600 mutant circulating cell-free tumor DNA as a tool for therapeutic monitoring in metastatic melanoma patients treated with BRAF/MEK inhibitors
Q55016615Quantitative monitoring of circulating tumor DNA predicts response of cutaneous metastatic melanoma to anti-PD1 immunotherapy.
Q43274590Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma
Q38856722Targeted agents and immunotherapies: optimizing outcomes in melanoma
Q88319624Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification
Q37244501Technological advances in precision medicine and drug development
Q97646131The Current State of Molecular Testing in the BRAF-Mutated Melanoma Landscape
Q48143437The Value of Cell-free DNA for Molecular Pathology
Q52686846The brim of uncertainty in adjuvant treatment of melanoma.
Q64078507The emerging role of cell-free DNA as a molecular marker for cancer management
Q92378915Tumour biomarkers-Tracing the molecular function and clinical implication
Q56890934Update on systemic therapy for advanced cutaneous melanoma and recent development of novel drugs
Q93040523Use of extracellular vesicles from lymphatic drainage as surrogate markers of melanoma progression and BRAF V600E mutation
Q49298466Use of phosphodiesterase type 5 inhibitors and risk of melanoma: a meta-analysis of observational studies
Q40460053Using circulating cell-free DNA to monitor personalized cancer therapy.
Q48233659Variants with a low allele frequency detected in genomic DNA affect the accuracy of mutation detection in cell-free DNA by next-generation sequencing.

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