Inhibition of host and viral translation during vesicular stomatitis virus infection. eIF2 is responsible for the inhibition of viral but not host translation.

scientific article published on 10 February 2005

Inhibition of host and viral translation during vesicular stomatitis virus infection. eIF2 is responsible for the inhibition of viral but not host translation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M501156200
P698PubMed publication ID15705563

P50authorJohn ConnorQ37368402
P2093author name stringDouglas S Lyles
P2860cites workRegulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alphaQ24540258
The Cell-Rounding Activity of the Vesicular Stomatitis Virus Matrix Protein Is due to the Induction of Cell DeathQ24679521
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translationQ27860920
PKR; a sentinel kinase for cellular stressQ28137774
Translational control is required for the unfolded protein response and in vivo glucose homeostasisQ28204066
The role of IFN-gamma in immune responses to viral infections of the central nervous systemQ28211049
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKRQ28588429
The matrix protein of vesicular stomatitis virus inhibits nucleocytoplasmic transport when it is in the nucleus and associated with nuclear pore complexesQ33605916
The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.Q33811639
Matrix protein and another viral component contribute to induction of apoptosis in cells infected with vesicular stomatitis virusQ33870184
Translational control of viral gene expression in eukaryotesQ33935121
Cytopathogenesis and inhibition of host gene expression by RNA virusesQ34010277
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agentsQ34273164
Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1Q34348314
Hijacking the translation apparatus by RNA virusesQ34774574
Ability of the matrix protein of vesicular stomatitis virus to suppress beta interferon gene expression is genetically correlated with the inhibition of host RNA and protein synthesisQ34857223
Translation initiation and viral tricksQ35084366
Stress-induced gene expression requires programmed recovery from translational repressionQ39735685
Replication and cytopathic effect of oncolytic vesicular stomatitis virus in hypoxic tumor cells in vitro and in vivoQ39756181
Defects in translational regulation mediated by the alpha subunit of eukaryotic initiation factor 2 inhibit antiviral activity and facilitate the malignant transformation of human fibroblastsQ40589545
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infectionQ40863327
Initiation of protein synthesis from the A site of the ribosomeQ41758609
Defective translational control facilitates vesicular stomatitis virus oncolysisQ42831942
Catalytic utilization of eIF-2 and mRNA binding proteins are limiting in lysates from vesicular stomatitis virus infected L cellsQ44377416
PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependentQ44864022
Further studies on the inhibition of cellular protein synthesis by vesicular stomatitis virusQ45800659
A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPasesQ48014886
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectvesicular stomatitisQ11549084
P304page(s)13512-13519
P577publication date2005-02-10
P1433published inJournal of Biological ChemistryQ867727
P1476titleInhibition of host and viral translation during vesicular stomatitis virus infection. eIF2 is responsible for the inhibition of viral but not host translation.
P478volume280