A DNA vaccine encoding genetic fusions of carcinoembryonic antigen (CEA) and granulocyte/macrophage colony-stimulating factor (GM-CSF).

scientific article

A DNA vaccine encoding genetic fusions of carcinoembryonic antigen (CEA) and granulocyte/macrophage colony-stimulating factor (GM-CSF). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2004.08.043
P698PubMed publication ID15652670

P50authorTheresa V StrongQ80080293
P2093author name stringPierre L Triozzi
Antonio Guerrero
Jose Lima
Denise R Shaw
Connie Jenkins
P2860cites workDNA vaccines: immunology, application, and optimization*Q28145651
The dendritic cell system and its role in immunogenicityQ29619870
Uses of granulocyte-macrophage colony-stimulating factor in vaccine developmentQ33901564
Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cellsQ33926746
Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine.Q33943869
The potential of DNA vaccination against tumor-associated antigens for antitumor therapyQ34574683
C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritisQ35126948
Quantitating cellular immune responses to cancer vaccines.Q35185254
CEA-based vaccinesQ35195921
Growth of factor-dependent hemopoietic precursor cell linesQ36344083
Vaccination with syngeneic, lymphoma-derived immunoglobulin idiotype combined with granulocyte/macrophage colony-stimulating factor primes mice for a protective T-cell responseQ37305644
Production of a single chain anti-CEA antibody from the hybridoma cell line T84.66 using a modified colony-lift selection procedure to detect antigen-positive ScFv bacterial clonesQ41055569
Evaluation of human carcinoembryonic-antigen (CEA)-transduced and non-transduced murine tumors as potential targets for anti-CEA therapiesQ41581372
Prevention of neonatal tolerance by a plasmid encoding granulocyte-macrophage colony stimulating factorQ44355356
First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host responseQ44570059
Antitumor effect induced by granulocyte/macrophage-colony-stimulating factor gene-modified tumor vaccination: comparison of adenovirus- and retrovirus-mediated genetic transductionQ44673161
A DNA vaccine encoding the 42 kDa C-terminus of merozoite surface protein 1 of Plasmodium falciparum induces antibody, interferon-gamma and cytotoxic T cell responses in rhesus monkeys: immuno-stimulatory effects of granulocyte macrophage-colony stiQ47899404
Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patientsQ47918537
Bm86 antigen induces a protective immune response against Boophilus microplus following DNA and protein vaccination in sheepQ63408765
Non-proteolytic release of carcinoembryonic antigen from normal human colonic epithelial cells cultured in collagen gelQ72021331
A targeted DNA vaccine augments the natural immune response to self TNF-alpha and suppresses ongoing adjuvant arthritisQ73163207
Polyethylene glycol-modified GM-CSF expands CD11b(high)CD11c(high) but notCD11b(low)CD11c(high) murine dendritic cells in vivo: a comparative analysis with Flt3 ligandQ73910703
Co-immunization with DNA vaccines expressing granulocyte-macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity, but not protective efficacy against Mycobacterium tuberculosisQ77419307
Co-expression of granulocyte-macrophage colony-stimulating factor with antigen enhances humoral and tumor immunity after DNA vaccinationQ77568949
Construction and characterization of a chimeric fusion protein consisting of an anti-idiotype antibody mimicking a breast cancer-associated antigen and the cytokine GM-CSFQ77915690
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)1273-1283
P577publication date2005-01-01
P1433published inVaccineQ7907941
P1476titleA DNA vaccine encoding genetic fusions of carcinoembryonic antigen (CEA) and granulocyte/macrophage colony-stimulating factor (GM-CSF)
P478volume23

Reverse relations

cites work (P2860)
Q33327757Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunity
Q40379085Enhanced transduction of mouse bone marrow-derived dendritic cells by repetitive infection with self-complementary adeno-associated virus 6 combined with immunostimulatory ligands
Q37540578Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma.

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