A model for GFR alpha 4 function and a potential modifying role in multiple endocrine neoplasia 2.

scientific article

A model for GFR alpha 4 function and a potential modifying role in multiple endocrine neoplasia 2. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1021470774
P356DOI10.1038/SJ.ONC.1207826
P698PubMed publication ID15592530
P5875ResearchGate publication ID8134759

P50authorBrad S ThomasQ59292371
P2093author name stringThomas J McDonald
Scott D Andrew
Peter J Ainsworth
Lois M Mulligan
Sherryl A M Taylor
Karen J Harrison
Judith B Vanhorne
P2860cites workGlial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteinsQ24683773
The GDNF family ligands and receptors - implications for neural developmentQ28144957
GDNF family neurotrophic factor signaling: four masters, one servant?Q28198154
Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinaseQ28575205
Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephinQ28577124
Over-representation of a germline variant in the gene encoding RET co-receptor GFRalpha-1 but not GFRalpha-2 or GFRalpha-3 in cases with sporadic medullary thyroid carcinoma.Q33947467
Cloning and characterization of the human GFRA2 locus and investigation of the gene in Hirschsprung diseaseQ33951721
Multiple endocrine neoplasia type 2 and RET: from neoplasia to neurogenesisQ34080215
Chromosome 20 deletion in human multiple endocrine neoplasia types 2A and 2B: a double-blind studyQ36258020
Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cellsQ38305599
Genetic analysis of RET, GFR alpha 1 and GDNF genes in Spanish families with multiple endocrine neoplasia type 2A.Q40735434
Determinants of ligand binding specificity in the glial cell line-derived neurotrophic factor family receptor alpha S.Q40851328
Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell developmentQ40872912
GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephinQ41008328
Familial medullary thyroid carcinoma: clinical variability and low aggressiveness associated with RET mutation at codon 804.Q42519738
Expression of the ret proto-oncogene product in human normal and neoplastic tissues of neural crest originQ48159699
Estimation of risk of inherited medullary thyroid carcinoma in apparent sporadic patients.Q52067452
Genetic events in tumour initiation and progression in multiple endocrine neoplasia type 2Q72076158
Update on the MEN 2A c804 RET mutation: is prophylactic thyroidectomy indicated?Q73292314
Variable expressivity of familial medullary thyroid carcinoma (FMTC) due to a RET V804M (GTG-->ATG) mutationQ73943430
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmultiple endocrine neoplasiaQ1553018
P304page(s)1091-1097
P577publication date2005-02-01
P1433published inOncogeneQ1568657
P1476titleA model for GFR alpha 4 function and a potential modifying role in multiple endocrine neoplasia 2
P478volume24

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cites work (P2860)
Q49017365Asthma severity, polymorphisms in 20p13 and their interaction with tobacco smoke exposure
Q36111935Molecular genetics of multiple endocrine neoplasia types 1 and 2.
Q36960954RET signaling in endocrine tumors: delving deeper into molecular mechanisms.
Q47137356The GDNF Family: A Role in Cancer?
Q40184745The mouse soluble GFRalpha4 receptor activates RET independently of its ligand persephin