TNF receptor associated factor 6

mammalian protein found in Homo sapiens

Wikidata entity: Q4050614



P682 biological process ... Q1612119 (immune response) immune response
P682 biological process ... Q3547638 (protein ubiquitination) protein ubiquitination
P682 biological process ... Q4941581 (bone resorption) bone resorption
P682 biological process ... Q12021553 (T-helper 1 type immune response) T-helper 1 type immune response
P682 biological process ... Q14599533 (negative regulation of apoptotic process) negative regulation of apoptotic process
P682 biological process ... Q14633878 (negative regulation of transcription by RNA polymerase II) negative regulation of transcription by RNA polymerase II
P682 biological process ... Q14633911 (regulation of apoptotic process) regulation of apoptotic process
P682 biological process ... Q14633919 (negative regulation of transcription, DNA-templated) negative regulation of transcription, DNA-templated
P682 biological process ... Q14761969 (positive regulation of NF-kappaB transcription factor activity) positive regulation of NF-kappaB transcription factor activity
P682 biological process ... Q14818018 (cellular response to DNA damage stimulus) cellular response to DNA damage stimulus
P682 biological process ... Q14818063 (positive regulation of apoptotic process) positive regulation of apoptotic process
P682 biological process ... Q14818068 (positive regulation of transcription by RNA polymerase II) positive regulation of transcription by RNA polymerase II
P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q952019 (bone remodeling) bone remodeling
P682 biological process ... Q1121544 (ossification) ossification
P682 biological process ... Q14852023 (response to interleukin-1) response to interleukin-1
P682 biological process ... Q14859605 (activation of NF-kappaB-inducing kinase activity) activation of NF-kappaB-inducing kinase activity
P682 biological process ... Q14859951 (odontogenesis of dentin-containing tooth) odontogenesis of dentin-containing tooth
P682 biological process ... Q14859963 (cell development) cell development
P682 biological process ... Q14860454 (positive regulation of protein ubiquitination) positive regulation of protein ubiquitination
P682 biological process ... Q14860462 (protein autoubiquitination) protein autoubiquitination
P682 biological process ... Q14860509 (activation of protein kinase activity) activation of protein kinase activity
P682 biological process ... Q14860557 (osteoclast differentiation) osteoclast differentiation
P682 biological process ... Q14863107 (cytokine-mediated signaling pathway) cytokine-mediated signaling pathway
P682 biological process ... Q14863111 (cellular response to lipopolysaccharide) cellular response to lipopolysaccharide
P682 biological process ... Q14863112 (cellular response to cytokine stimulus) cellular response to cytokine stimulus
P682 biological process ... Q14863363 (animal organ morphogenesis) animal organ morphogenesis
P682 biological process ... Q14863376 (protein polyubiquitination) protein polyubiquitination
P682 biological process ... Q14863701 (positive regulation of smooth muscle cell proliferation) positive regulation of smooth muscle cell proliferation
P682 biological process ... Q14863970 (T cell receptor signaling pathway) T cell receptor signaling pathway
P682 biological process ... Q14864035 (positive regulation of I-kappaB kinase/NF-kappaB signaling) positive regulation of I-kappaB kinase/NF-kappaB signaling
P682 biological process ... Q14864234 (protein deubiquitination) protein deubiquitination
P682 biological process ... Q14864250 (protein K63-linked ubiquitination) protein K63-linked ubiquitination
P682 biological process ... Q14864461 (positive regulation of DNA-binding transcription factor activity) positive regulation of DNA-binding transcription factor activity
P682 biological process ... Q14864517 (positive regulation of T cell proliferation) positive regulation of T cell proliferation
P682 biological process ... Q14864542 (toll-like receptor signaling pathway) toll-like receptor signaling pathway
P682 biological process ... Q14864543 (MyD88-dependent toll-like receptor signaling pathway) MyD88-dependent toll-like receptor signaling pathway
P682 biological process ... Q14864810 (interleukin-1-mediated signaling pathway) interleukin-1-mediated signaling pathway
P682 biological process ... Q14865490 (myeloid dendritic cell differentiation) myeloid dendritic cell differentiation
P682 biological process ... Q14874299 (Fc-epsilon receptor signaling pathway) Fc-epsilon receptor signaling pathway
P682 biological process ... Q14876758 (antigen processing and presentation of exogenous peptide antigen via MHC class II) antigen processing and presentation of exogenous peptide antigen via MHC class II
P682 biological process ... Q14885826 (neural tube closure) neural tube closure
P682 biological process ... Q14897628 (positive regulation of JUN kinase activity) positive regulation of JUN kinase activity
P682 biological process ... Q14897649 (JNK cascade) JNK cascade
P682 biological process ... Q14897868 (membrane protein intracellular domain proteolysis) membrane protein intracellular domain proteolysis
P682 biological process ... Q14904250 (positive regulation of osteoclast differentiation) positive regulation of osteoclast differentiation
P682 biological process ... Q14904612 (positive regulation of transcription regulatory region DNA binding) positive regulation of transcription regulatory region DNA binding
P682 biological process ... Q14905553 (toll-like receptor 9 signaling pathway) toll-like receptor 9 signaling pathway
P682 biological process ... Q14905686 (positive regulation of NIK/NF-kappaB signaling) positive regulation of NIK/NF-kappaB signaling
P682 biological process ... Q14908208 (nucleotide-binding oligomerization domain containing signaling pathway) nucleotide-binding oligomerization domain containing signaling pathway
P682 biological process ... Q14912635 (positive regulation of lipopolysaccharide-mediated signaling pathway) positive regulation of lipopolysaccharide-mediated signaling pathway
P682 biological process ... Q14914323 (positive regulation of T cell cytokine production) positive regulation of T cell cytokine production
P682 biological process ... Q14914324 (positive regulation of interleukin-2 production) positive regulation of interleukin-2 production
P682 biological process ... Q14916317 (immune system process) immune system process
P682 biological process ... Q21095171 (I-kappaB kinase/NF-kappaB signaling) I-kappaB kinase/NF-kappaB signaling
P682 biological process ... Q21095173 (stimulatory C-type lectin receptor signaling pathway) stimulatory C-type lectin receptor signaling pathway
P682 biological process ... Q21097277 (regulation of I-kappaB kinase/NF-kappaB signaling) regulation of I-kappaB kinase/NF-kappaB signaling
P682 biological process ... Q24490184 (positive regulation of leukocyte adhesion to vascular endothelial cell) positive regulation of leukocyte adhesion to vascular endothelial cell
P681 cell component ... Q40260 (nucleus) nucleus
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q220599 (cytosol) cytosol
P681 cell component ... Q573950 (lipid droplet) lipid droplet
P681 cell component ... Q5058180 (cell cortex) cell cortex
P681 cell component ... Q14330632 (perinuclear region of cytoplasm) perinuclear region of cytoplasm
P681 cell component ... Q14860543 (endosome membrane) endosome membrane
P681 cell component ... Q14877624 (cytoplasmic side of plasma membrane) cytoplasmic side of plasma membrane
P681 cell component ... Q14914322 (CD40 receptor complex) CD40 receptor complex
P681 cell component ... Q22325163 (protein-containing complex) protein-containing complex
P702 encoded by ... Q14914325 (TRAF6) TRAF6
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P692 Gene Atlas image CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20TRAF6%20205558%20at%20fs.png ???
P527 has part(s) ... Q24770850 (Zinc finger, TRAF-type) Zinc finger, TRAF-type
P527 has part(s) ... Q24775533 (MATH/TRAF domain) MATH/TRAF domain
P527 has part(s) ... Q24783297 (Zinc finger, RING-type, conserved site) Zinc finger, RING-type, conserved site
P527 has part(s) ... Q24788168 (Zinc finger, RING-type) Zinc finger, RING-type
P527 has part(s) ... Q43921252 (TNF receptor-associated factor 6, MATH domain) TNF receptor-associated factor 6, MATH domain
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q13667380 (metal ion binding) metal ion binding
P680 molecular function ... Q14633865 (zinc ion binding) zinc ion binding
P680 molecular function ... Q14633869 (ubiquitin protein ligase binding) ubiquitin protein ligase binding
P680 molecular function ... Q14762994 (identical protein binding) identical protein binding
P680 molecular function ... Q14817984 (protein kinase binding) protein kinase binding
P680 molecular function ... Q14817992 (protein N-terminus binding) protein N-terminus binding
P680 molecular function ... Q14840131 (transferase activity) transferase activity
P680 molecular function ... Q14860441 (ubiquitin-protein transferase activity) ubiquitin-protein transferase activity
P680 molecular function ... Q14865042 (thioesterase binding) thioesterase binding
P680 molecular function ... Q14865603 (histone deacetylase binding) histone deacetylase binding
P680 molecular function ... Q14866094 (tumor necrosis factor receptor binding) tumor necrosis factor receptor binding
P680 molecular function ... Q14906652 (mitogen-activated protein kinase kinase kinase binding) mitogen-activated protein kinase kinase kinase binding
P680 molecular function ... Q14907692 (protein kinase B binding) protein kinase B binding
P680 molecular function ... Q21095456 (ubiquitin protein ligase activity) ubiquitin protein ligase activity
P680 molecular function ... Q21107991 (ubiquitin conjugating enzyme binding) ubiquitin conjugating enzyme binding
P361 part of ... Q24740555 (TNF receptor-associated factor 6) TNF receptor-associated factor 6
P361 part of ... Q24769143 (TRAF-like) TRAF-like
P361 part of ... Q24786519 (Zinc finger, RING/FYVE/PHD-type) Zinc finger, RING/FYVE/PHD-type
P361 part of ... Q83140047 (Zinc finger, TRAF-type, protein family) Zinc finger, TRAF-type, protein family
P361 part of ... Q83145564 (MATH/TRAF domain, protein family) MATH/TRAF domain, protein family
P361 part of ... Q83166628 (Zinc finger, RING-type, protein family) Zinc finger, RING-type, protein family
P361 part of ... Q83170871 (TNF receptor-associated factor 6, MATH domain, protein family) TNF receptor-associated factor 6, MATH domain, protein family
P361 part of ... Q95351991 (Zinc finger, RING-type, conserved site, protein family) Zinc finger, RING-type, conserved site, protein family

External Ids
P705Ensembl protein IDENSP00000337853
P705Ensembl protein IDENSP00000433623
P638PDB structure ID4Z8M
P638PDB structure ID1LB6
P638PDB structure ID3HCT
P638PDB structure ID3HCU
P638PDB structure ID1LB4
P638PDB structure ID1LB5
P638PDB structure ID2ECI
P638PDB structure ID2JMD
P638PDB structure ID3HCS
P637RefSeq protein IDNP_004611
P637RefSeq protein IDNP_665802
P637RefSeq protein IDXP_016873709
P352UniProt protein IDQ9Y4K3

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