review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0959-437X(95)90058-6 |
P698 | PubMed publication ID | 7749331 |
P2093 | author name string | Oren M | |
Haffner R | |||
P2860 | cites work | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 |
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes | Q24608783 | ||
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations | Q27730815 | ||
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR | Q27730817 | ||
WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA | Q29615251 | ||
DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways | Q36647845 | ||
p53-mediated cell death: relationship to cell cycle control | Q36675212 | ||
Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. | Q38313400 | ||
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein | Q38313694 | ||
Complementation by wild-type p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression | Q40657202 | ||
How loops, beta sheets, and alpha helices help us to understand p53. | Q40694267 | ||
Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal. | Q40791236 | ||
Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation. | Q40792701 | ||
The tumor suppressor genes | Q40856821 | ||
p53-catalyzed annealing of complementary single-stranded nucleic acids | Q40873109 | ||
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes | Q41454039 | ||
Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells | Q41483255 | ||
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. | Q41563742 | ||
The effects of SV40 large T antigen and p53 on nuclear transport capacity in BALB/c 3T3 cells | Q42796110 | ||
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. | Q45993768 | ||
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen | Q48084448 | ||
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. | Q52214399 | ||
Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. | Q52512094 | ||
p53 domains: identification and characterization of two autonomous DNA-binding regions. | Q52544476 | ||
Transcriptional activation by p53 correlates with suppression of growth but not transformation. | Q53468212 | ||
p53, guardian of Rb | Q59068113 | ||
No room at the p53 inn | Q59093958 | ||
Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1 | Q71644976 | ||
p53-dependent apoptosis suppresses tumor growth and progression in vivo | Q72149266 | ||
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots | Q72693767 | ||
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development | Q72718760 | ||
Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53 | Q72871721 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 84-90 | |
P577 | publication date | 1995-02-01 | |
P1433 | published in | Current Opinion in Genetics & Development | Q13505684 |
P1476 | title | Biochemical properties and biological effects of p53. | |
P478 | volume | 5 |
Q34761984 | A functional p53-responsive intronic promoter is contained within the humanmdm2gene |
Q40019792 | A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis |
Q48058940 | A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeast Schizosaccharomyces pombe |
Q28574858 | A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis |
Q36546016 | Activities and response to DNA damage of latent and active sequence-specific DNA binding forms of mouse p53. |
Q41049816 | Alteration of p53 protein in C3H/10T1/2 cells morphologically transformed by gamma-rays in stationary phase. |
Q73928775 | Analysis of bcl-2 in sporadic breast carcinoma |
Q41076902 | Anti-apoptotic activity of low levels of wild-type p53. |
Q78192930 | Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant |
Q41290168 | Apoptosis and gastrointestinal pharmacology. |
Q50974402 | Apoptosis in steroidogenic cells: structure-function analysis. |
Q41515231 | Apoptosis: an overview of the process and its relevance in disease. |
Q48482815 | BCL-2 family protein expression in human malignant glioma: a clinical-pathological correlative study |
Q35847043 | Cell type-specific inhibition of p53-mediated apoptosis by mdm2. |
Q40889956 | Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells |
Q36019930 | Conformation-dependent phosphorylation of p53. |
Q48027293 | DAP genes: novel apoptotic genes isolated by a functional approach to gene cloning |
Q59083516 | DAP kinase links the control of apoptosis to metastasis |
Q28277623 | Death-associated proteins: from gene identification to the analysis of their apoptotic and tumour suppressive functions |
Q42828172 | Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice |
Q31396053 | Differences in the effects of HMG-CoA reductase inhibitors on proliferation and viability of smooth muscle cells in culture |
Q41157654 | Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells |
Q39841731 | Effect of inducible expressed human cytomegalovirus immediate early 86 protein on cell apoptosis |
Q73401624 | Effects of dehydroepiandrosterone and calorie restriction on the Bcl-2/Bax-mediated apoptotic pathway in p53-deficient mice |
Q53625566 | Effects of maternal uninephrectomy on the development of fetal rat kidney: apoptosis and the expression of oncogenes. |
Q24633970 | FinO is an RNA chaperone that facilitates sense-antisense RNA interactions |
Q36561445 | Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo. |
Q35633059 | Functions of pRb and p53: what's the connection? |
Q41037063 | Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations |
Q73283449 | HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX |
Q41204966 | Human T-cell leukemia virus type I tax masks c-Myc function through a cAMP-dependent pathway |
Q39872769 | Human cytomegalovirus IE1 and IE2 proteins block apoptosis |
Q73271533 | Human polyomavirus BK (BKV) and neuroblastoma: mechanisms of oncogenic action and possible strategy for novel treatment |
Q53461564 | Induction of apoptosis in HeLa cells by trans-activation-deficient p53 |
Q41071070 | Induction of p53 protein expression by sodium arsenite |
Q44123359 | Involvement of reactive oxygen species in arsenite-induced downregulation of phospholipid hydroperoxide glutathione peroxidase in human epidermoid carcinoma A431 cells |
Q59098941 | Life (and death) in a malignant tumour |
Q37474256 | MEKK1/JNK signaling stabilizes and activates p53. |
Q41290133 | Molecular and clinical aspects of apoptosis |
Q27851503 | Mutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancer |
Q33780955 | Noise cancellation: viral fine tuning of the cellular environment for its own genome replication. |
Q23915398 | PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo |
Q23918117 | Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells |
Q33834813 | Phenotype vs genotype in the evolution of astrocytic brain tumors |
Q34459889 | Protein-protein interfaces: mimics and inhibitors |
Q38327560 | RETRACTED: Alteration of p73 in acute myelogenous leukemia |
Q74355214 | RNA polymerase III transcription can be derepressed by oncogenes or mutations that compromise p53 function in tumours and Li-Fraumeni syndrome |
Q41101646 | Ras activation leads to cell proliferation or apoptotic cell death upon interleukin-2 stimulation or lymphokine deprivation, respectively |
Q28243213 | Recruitment of p300/CBP in p53-dependent signal pathways |
Q40902101 | Reduced expression of p33(ING1) and the relationship with p53 expression in human gastric cancer |
Q33828413 | Regulation of MCP-1 chemokine transcription by p53 |
Q38352373 | Regulation of mutant p53 temperature-sensitive DNA binding. |
Q36556427 | Regulation of p53-mediated apoptosis and cell cycle arrest by Steel factor |
Q24552501 | Repression of RNA polymerase I transcription by the tumor suppressor p53 |
Q24336020 | Repression of p53-mediated transcription by MDM2: a dual mechanism |
Q41589773 | Role of extracellular matrix, growth factors and proto-oncogenes in metanephric development |
Q54569740 | Role of ribonucleotide reductase and deoxynucleotide pools in the oxygen-dependent control of DNA replication in Ehrlich ascites cells. |
Q33781230 | Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53. |
Q40953874 | Strategies and applications of DNA level diagnosis in genetic diseases: past experiences and future directions. |
Q36292987 | Suppression of tumorigenic and metastatic potentials of human melanoma cell lines by mutated (143 Val-Ala) p53. |
Q24551106 | Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response |
Q74486048 | The expression of p53, c-erbB-1 and c-erbB-2 molecules and their correlation with prognostic markers in patients with head and neck tumors |
Q77144377 | The immunomodulating glycoprotein extract from Klebsiella pneumoniae RU 41740 exerts a suppressive effect on human monocyte death by apoptosis |
Q42454112 | The p53 tumor suppressor inhibits transcription of the TATA-less mouse DP1 promoter. |
Q41099842 | The recognition of DNA damage |
Q40023735 | Transcriptional activation by p53 of the human type IV collagenase (gelatinase A or matrix metalloproteinase 2) promoter |
Q35903285 | Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis |
Q33886271 | Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis |
Q35878052 | Transrepression of lck gene expression by human T-cell leukemia virus type 1-encoded p40tax |
Q41625163 | Tumor suppressor genes and human cancer |
Q40752768 | Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A. |
Q52192096 | p53 activity is essential for normal development in Xenopus. |
Q33888115 | p53 binds and represses the HBV enhancer: an adjacent enhancer element can reverse the transcription effect of p53 |
Q48799379 | p53 expression induces apoptosis in hippocampal pyramidal neuron cultures. |
Q43643342 | p53 gene alteration and protein expression in Iranian women with infiltrative ductal breast carcinoma. |
Q42645736 | p53 is a general repressor of RNA polymerase III transcription |
Q42468055 | p53 represses ribosomal gene transcription |
Q74185669 | p53-dependent apoptosis and transcription of p21waf/cip1/sdi1 in SCID mice following gamma-irradiation |
Q33868917 | p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding |
Q41091013 | p73 is a simian [correction of human] p53-related protein that can induce apoptosis |
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