Inactive O6-methylguanine-DNA methyltransferase in human cells

scientific article published on November 25, 1992

Inactive O6-methylguanine-DNA methyltransferase in human cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/20.22.6081
P953full work available at URLhttps://europepmc.org/articles/PMC334476
https://europepmc.org/articles/PMC334476?pdf=render
P932PMC publication ID334476
P698PubMed publication ID1461738

P2093author name stringP. Karran
B. Rydberg
N. Zhukovskaya
P2860cites workCorrelation between DNA methylation and expression of O6-methylguanine-DNA methyltransferase gene in cultured human tumor cellsQ67532821
Use of antibodies to human O6-alkylguanine-DNA alkyltransferase to study the content of this protein in cells treated with O6-benzylguanine or N-methyl-N'-nitro-N-nitrosoguanidineQ67975150
O6-alkyltransferase activity in normal human gastric mucosaQ68578947
O6-Methylguanine-DNA methyltransferase of human lymphoid cells: structural and kinetic properties and absence in repair-deficient cellsQ70255379
cDNA cloning and chromosomal assignment of the human O6-methylguanine-DNA methyltransferase. cDNA expression in Escherichia coli and gene expression in human cellsQ24337212
Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reactionQ24556507
Self-destruction and tolerance in resistance of mammalian cells to alkylation damageQ36277253
Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agentsQ37952773
Evidence for spontaneous conversion of Mex- to Mex+ in human lymphoblastoid cellsQ41206014
Genomic differences between O6-methylguanine-DNA methyltransferase proficient (Mex+) and deficient (Mex-) cell lines: possible role of genetic and epigenetic changes in conversion of Mex+ into Mex-Q41634016
Spectrum of spontaneously occurring mutations in the hprt gene of V79 Chinese hamster cellsQ41640303
Cell-Cycle Associated Transcriptional Regulation of Ribonucleotide Reductase in L1210 Leukemia Cells and Drug-Resistant VariantsQ41705983
Evidence for allelic exclusion in Chinese hamster ovary cellsQ41727336
Coregulation of the human O6-methylguanine-DNA methyltransferase with two unrelated genes that are closely linkedQ41742698
Comparison of O-6-methylguanine DNA methyltransferase (MGMT) mRNA levels in Mer+ and Mer- human tumor cell lines containing the MGMT gene by the polymerase chain reaction techniqueQ41749242
Environmental mutagens that induce the adaptive response to alkylating agents in Escherichia coliQ41968976
Expression plasmid containing the lambda PL promoter and cI857 repressorQ46325331
Expression of O6-methylguanine-DNA methyltransferase in malignant human glioma cell lines.Q53496348
Production of antibodies to peptide sequences present in human O6-alkylguanine-DNA alkyltransferase and their use to detect this protein in cell extracts.Q53496551
Interindividual variation in the activity of O6-methyl guanine-DNA methyltransferase and uracil-DNA glycosylase in human organs.Q53556776
Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro.Q53566920
O6-Methylguanine-DNA methyltransferase in human cells.Q55488873
P433issue22
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)6081-6090
P577publication date1992-11-01
1992-11-25
P1433published inNucleic Acids ResearchQ135122
P1476titleInactive O6-methylguanine-DNA methyltransferase in human cells
P478volume20

Reverse relations

cites work (P2860)
Q59134092Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier
Q28388726Inter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair research
Q33606811Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis
Q40473972Structure, Function, and Inhibition of O6-Alkylguanine-DNA Alkyltransferase
Q41193565The role of DNA repair in the prevention of cancer
Q30428760Understanding and manipulating O6-methylguanine-DNA methyltransferase expression

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