| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.C400289200 |
| P698 | PubMed publication ID | 15247281 |
| P50 | author | Paul J Hertzog | Q38359228 |
| Elizabeth K Brint | Q54400743 | ||
| Luke A. J. O'Neill | Q24209151 | ||
| Ashley Mansell | Q37376445 | ||
| P2093 | author name string | Jodee A Gould | |
| P2860 | cites work | TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction | Q40675827 |
| Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. | Q40870297 | ||
| High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization | Q40937646 | ||
| CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization | Q42060069 | ||
| Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction | Q24291653 | ||
| Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3... | Q24297037 | ||
| Distinct molecular mechanism for initiating TRAF6 signalling | Q24302174 | ||
| Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta | Q24311833 | ||
| Transactivation by the p65 subunit of NF-kappaB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1 | Q24550930 | ||
| LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF | Q24672442 | ||
| TIRAP: an adapter molecule in the Toll signaling pathway | Q28214613 | ||
| TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway | Q28505835 | ||
| The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors | Q28511605 | ||
| Identification of Lps2 as a key transducer of MyD88-independent TIR signalling | Q28587545 | ||
| Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling | Q28646137 | ||
| Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. | Q34160547 | ||
| TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta. | Q34266420 | ||
| Regulation of the transcriptional activity of the nuclear factor-kappaB p65 subunit. | Q34816285 | ||
| A universal role for MyD88 in TLR/IL-1R-mediated signaling | Q34825992 | ||
| The Toll-IL-1 receptor adaptor family grows to five members. | Q35155932 | ||
| TIR domain-containing adaptors define the specificity of TLR signaling | Q35617615 | ||
| P433 | issue | 36 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | toll-like receptor | Q408004 |
| NF-κB | Q411114 | ||
| P1104 | number of pages | 4 | |
| P304 | page(s) | 37227-37230 | |
| P577 | publication date | 2004-07-09 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4. | |
| P478 | volume | 279 |
| Q37018307 | A (selective) history of Australian involvement in cytokine biology |
| Q41595595 | A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis. |
| Q41065262 | A frequent hypofunctional IRAK2 variant is associated with reduced spontaneous hepatitis C virus clearance |
| Q36092598 | Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia |
| Q36330373 | Association between the TLR2 Arg753Gln polymorphism and the risk of sepsis: a meta-analysis |
| Q38382435 | Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility |
| Q43252748 | Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes |
| Q40431320 | Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide |
| Q34121591 | Differential induction of innate immune responses by synthetic lipid a derivatives |
| Q36558731 | Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut. |
| Q37238784 | Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock |
| Q33651487 | Functional characterization of bovine TIRAP and MyD88 in mediating bacterial lipopolysaccharide-induced endothelial NF-kappaB activation and apoptosis |
| Q36837528 | Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein |
| Q38129869 | IL-17A and Th17 cells in lung inflammation: an update on the role of Th17 cell differentiation and IL-17R signaling in host defense against infection. |
| Q40132444 | Identification of binding sites for myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 in MyD88 adapter-like (Mal). |
| Q35011883 | Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype |
| Q39919544 | Interleukin-1 receptor type 1 is a substrate for gamma-secretase-dependent regulated intramembrane proteolysis. |
| Q58715644 | Investigation of interactions between TLR2, MyD88 and TIRAP by bioluminescence resonance energy transfer is hampered by artefacts of protein overexpression |
| Q24310427 | Mal connects TLR2 to PI3Kinase activation and phagocyte polarization |
| Q38132108 | Mal, more than a bridge to MyD88. |
| Q83653839 | Meta-analysis on the association of TIRAP S180L variant and tuberculosis susceptibility |
| Q37215779 | Meta-analysis on the associations of TLR2 gene polymorphisms with pulmonary tuberculosis susceptibility among Asian populations |
| Q53215488 | Mincle suppresses Toll-like receptor 4 activation. |
| Q37433320 | MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses. |
| Q47822234 | Mycobacterium tuberculosis escapes from the phagosomes of infected human osteoclasts reprograms osteoclast development via dysregulation of cytokines and chemokines. |
| Q37526582 | Mycobacterium tuberculosis, autoimmunity, and vitamin D. |
| Q54455445 | Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. |
| Q36080307 | Poxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactions |
| Q37150726 | Primer: Toll-like receptor signaling pathways--what do rheumatologists need to know? |
| Q24336085 | Protein kinase Cdelta binds TIRAP/Mal to participate in TLR signaling |
| Q37132899 | RETRACTED: GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38 |
| Q37167886 | SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria |
| Q42206046 | STAT1 plays a role in TLR signal transduction and inflammatory responses. |
| Q27678387 | Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling |
| Q27655822 | Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling |
| Q36898672 | Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins |
| Q40328896 | Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation |
| Q35956532 | TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia. |
| Q36246129 | The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4. |
| Q29615457 | The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling |
| Q36875508 | The negative regulation of Toll-like receptor and associated pathways |
| Q36898668 | The role of type I interferons in TLR responses. |
| Q58797369 | Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children |
| Q36453194 | Toll-like Receptors in the Vascular System: Sensing the Dangers Within |
| Q45207411 | Toll-like receptors promote inflammation in idiopathic inflammatory myopathies |
| Q24296469 | Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4 |
| Q42487146 | VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts. |
| Q40665532 | Vitamin D status, vitamin D receptor and toll like receptor-2 polymorphisms in tuberculous meningitis: a case-control study |
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