Inhibition of RNA polymerase II phosphorylation by a viral interferon antagonist

scientific article published on 17 May 2004

Inhibition of RNA polymerase II phosphorylation by a viral interferon antagonist is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M400938200
P698PubMed publication ID15150262

P50authorFriedemann WeberQ40182480
Daniel ThomasQ55190329
P2093author name stringRichard M Elliott
Gjon Blakqori
Otto Haller
Valentina Wagner
Nina Kessler
Marius Banholzer
P2860cites workA Novel RNA Polymerase II C-terminal Domain Phosphatase That Preferentially Dephosphorylates Serine 5Q24300798
Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.Q24533140
The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionQ24554329
hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongationQ24554421
The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domainQ24600925
Inhibition of Translation and Induction of Apoptosis by Bunyaviral Nonstructural Proteins Bearing Sequence Similarity to ReaperQ27481525
How cells respond to interferonsQ27861006
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcriptionQ28131686
Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-IIQ28218480
Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domainQ28343959
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivoQ28609049
Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processingQ29614768
A unified theory of gene expressionQ29615022
Interferons: cell signalling, immune modulation, antiviral response and virus countermeasuresQ29618978
P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase IIQ29620167
HIV-1 Tat protein increases transcriptional initiation and stabilizes elongationQ29620799
TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.Q33198557
Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 proteinQ33810694
Cytopathogenesis and inhibition of host gene expression by RNA virusesQ34010277
Human influenza viruses activate an interferon-independent transcription of cellular antiviral genes: outcome with influenza A virus is uniqueQ34099139
Lethal H5N1 influenza viruses escape host anti-viral cytokine responsesQ34146021
The virus battles: IFN induction of the antiviral state and mechanisms of viral evasionQ34234077
VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agentsQ34273164
Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1Q34348314
Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesisQ34625091
Regulation of transcription elongation by phosphorylationQ34816680
Ability of the matrix protein of vesicular stomatitis virus to suppress beta interferon gene expression is genetically correlated with the inhibition of host RNA and protein synthesisQ34857223
Antigenic drift, antigenic shift and interferon antagonists: how bunyaviruses counteract the immune systemQ34895197
Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon.Q35000433
A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3' end processing.Q35561598
Direct cleavage of human TATA-binding protein by poliovirus protease 3C in vivo and in vitroQ36661993
STAT1 is inactivated by a caspaseQ38337795
Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferonQ39593618
Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSsQ39601913
The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factorsQ39685168
Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell deathQ39776458
A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFbQ39895224
HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcriptionQ40727461
IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoffQ40756093
The Bunyamwera virus nonstructural protein NSs inhibits viral RNA synthesis in a minireplicon systemQ40823920
The transcriptional inhibitors, actinomycin D and alpha-amanitin, activate the HIV-1 promoter and favor phosphorylation of the RNA polymerase II C-terminal domainQ40951736
Defective RNAs in mosquito cells persistently infected with Bunyamwera virusQ41650074
Inhibition of host RNA polymerase II-dependent transcription by vesicular stomatitis virus results from inactivation of TFIID.Q42464743
LaCrosse virus gene expression in mammalian and mosquito cellsQ44149007
The C. elegans Tousled-like kinase (TLK-1) has an essential role in transcription.Q44653965
Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genesQ44734152
Inhibition of Ran guanosine triphosphatase-dependent nuclear transport by the matrix protein of vesicular stomatitis virusQ45762580
Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factorQ45772727
Viral Evasion of the Interferon System: Old Viruses, New TricksQ57017454
P433issue30
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)31471-31477
P577publication date2004-05-17
P1433published inJournal of Biological ChemistryQ867727
P1476titleInhibition of RNA polymerase II phosphorylation by a viral interferon antagonist
P478volume279