Dexrazoxane in the prevention of doxorubicin-induced cardiotoxicity

scientific article published on September 1994

Dexrazoxane in the prevention of doxorubicin-induced cardiotoxicity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1177/106002809402800912
P698PubMed publication ID7803884

P2093author name stringD F Thompson
C F Seifert
M E Nesser
P2860cites workPharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicinQ28317288
Reducing doxorubicin cardiotoxicity in the rat using deferred treatment with ADR-529Q28320156
ICRF-187 permits longer treatment with doxorubicin in women with breast cancerQ28324350
Risk factors for doxorubicin-induced congestive heart failureQ28328220
Effect of ICRF-187 pretreatment against doxorubicin-induced delayed cardiotoxicity in the ratQ28329176
A prospective randomized trial of ICRF-187 for prevention of cumulative doxorubicin-induced cardiac toxicity in women with breast cancerQ28329748
Adriamycin and Radiation: Synergistic CardiotoxicityQ28341547
Effect of ICRF-187 on doxorubicin-induced myocardial effects in the mouse and guinea pigQ28367382
Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinolQ33575389
Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitroQ33614685
Glutathione: interorgan translocation, turnover, and metabolismQ33979283
Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicinQ34718010
Toxicity profile of dexrazoxane (zinecardR, icrf-187, adr-529, nsc-169780), a modulator of doxorubicin cardiotoxicityQ37143331
Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicityQ37949829
A new insight into adriamycin-induced cardiotoxicityQ38012571
The anthracycline antineoplastic drugsQ40308244
Phase I study of doxorubicin, ICRF-187 and granulocyte/macrophage-colony-stimulating factorQ40738694
Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancerQ40783194
Amelioration of chronic anthracycline cardiotoxicity by ICRF-187 and other compoundsQ42208727
Inhibition of doxorubicin-initiated membrane damage by N-acetylcysteine: possible mediation by a thiol-dependent, cytosolic inhibitor of lipid peroxidationQ42210542
Early changes in human myocardial nuclei after doxorubicinQ42259964
Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusionQ42263291
Lethal and sublethal effects of the combination of doxorubicin and the bisdioxopiperazine, (+)-1,2,-bis (3-5-dioxopiperazinyl-1-yl) propane (ICRF 187), on murine sarcoma S180 in vitroQ45072345
Might adriamycinol contribute to adriamycin-induced cardiotoxicity?Q53832898
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectpreventionQ1717246
P304page(s)1063-1072
P577publication date1994-09-01
P1433published inAnnals of PharmacotherapyQ4767858
P1476titleDexrazoxane in the prevention of doxorubicin-induced cardiotoxicity
P478volume28

Reverse relations

cites work (P2860)
Q89231551A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish
Q37052852A recommended practical approach to the management of anthracycline-based chemotherapy cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology
Q33963576Adriamycin-induced heart failure: mechanism and modulation
Q35100669Altered responsiveness of the guinea-pig isolated ileum to smooth muscle stimulants and to electrical stimulation after in situ ischemia
Q74423004Anthracycline-induced acute cardiotoxicity in adults treated for leukaemia. Analysis of the clinico-pathological aspects of documented acute anthracycline-induced cardiotoxicity in patients treated for acute leukaemia at the University Hospital of Z
Q53428348Antioxidant inhibitors for cancer therapy.
Q46805568Cardioprotective effects of fullerenol C(60)(Oh)(24) on a single dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm
Q36174517Cardiotoxicity of cancer chemotherapy: implications for children
Q42538440Cardiotoxicity of doxorubicin: effects of 21-aminosteroids
Q46592609Carfilzomib-induced cardiotoxicity mitigated by dexrazoxane through inhibition of hypertrophic gene expression and oxidative stress in rats
Q36126521Dexrazoxane : a review of its use for cardioprotection during anthracycline chemotherapy
Q27345163Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice
Q44389042Doxorubicin cardiotoxicity: prevention of congestive heart failure with serial cardiac function monitoring with equilibrium radionuclide angiocardiography in the current era.
Q92677814Doxorubicin-Induced Cardiomyopathy in Children
Q34773776Doxorubicin-induced apoptosis: implications in cardiotoxicity
Q64104933Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency
Q38219831Historical perspective on the introduction and use of chemotherapy for the treatment of osteosarcoma
Q90653004In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents
Q41669706Melatonin Supplementation Ameliorates Energy Charge and Oxidative Stress Induced by Acute Exercise in Rat Heart Tissue
Q44558496Melatonin stimulates the activity of protective antioxidative enzymes in myocardial cells of rats in the course of doxorubicin intoxication
Q42153380Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats
Q35009418Minimising the long-term adverse effects of childhood leukaemia therapy
Q33982934Ozone-Oxidative Preconditioning Prevents Doxorubicin-induced Cardiotoxicity in Sprague-Dawley Rats
Q42861882Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury
Q24791372Protection against acute adriamycin-induced cardiotoxicity by garlic: role of endogenous antioxidants and inhibition of TNF-alpha expression
Q50082485Redox Paradox: A novel approach to therapeutics-resistant cancer
Q44086407Role of exogenous melatonin in reducing the nephrotoxic effect of daunorubicin and doxorubicin in the rat.
Q35852267Rust and corrosion in hematopoietic stem cell transplantation: the problem of iron and oxidative stress
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Q33427938The minipig as a new model for the evaluation of doxorubicin-induced chronic toxicity
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Q74601644Thermal preconditioning protects rat cardiac muscle cells from doxorubicin-induced apoptosis
Q49832269Topoisomerases as anticancer targets
Q73181060[The prevention of anthracycline-induced cardiomyopathy with a chelating agent (dexrazoxane = ICRF-187)]

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