Treatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in females

scientific article published on August 2003

Treatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in females is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0006-2952(03)00211-9
P698PubMed publication ID12907238

P2093author name stringBhalchandra A Diwan
David Kritchevsky
Lucy M Anderson
Richard J Calvert
Shirley Tepper
P2860cites workTissue distribution and quantitative analysis of estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouseQ28252945
The role of mitogen-activated protein (MAP) kinase in breast cancerQ30308930
Sex-specific expression of gastrin-releasing peptide receptor: relationship to smoking history and risk of lung cancerQ33885599
Follow-up study of patients randomized in the Scandinavian simvastatin survival study (4S) of cholesterol loweringQ33912099
K-ras p21 expression and activity in lung and lung tumorsQ34150023
'Smoke like a man, die like a man'?: a review of the relationship between gender, sex and lung cancerQ34369585
Annual report to the nation on the status of cancer, 1973-1996, with a special section on lung cancer and tobacco smokingQ34503196
Serum cholesterol and cancer risk: an epidemiologic perspectiveQ35706361
Cholestyramine promotes 7,12-dimethylbenzanthracene induced mammary cancer in Wistar ratsQ36027903
Statin use, hyperlipidaemia, and the risk of breast cancerQ36644431
Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductaseQ37024891
Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activityQ37108753
Wildtype Kras2 can inhibit lung carcinogenesis in miceQ40783010
Levels and membrane localization of the c-K-ras p21 protein in lungs of mice of different genetic strains and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and Aroclor 1254.Q41055103
Differential distribution and increased levels of ras proteins during lung developmentQ42529083
Characterization of skin tumor promotion by mirex: structure-activity relationships, sexual dimorphism and presence of Ha-ras mutationQ42558185
Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TEXCAPS): additional perspectives on tolerability of long-term treatment with lovastatinQ43604509
Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS): efficacy and tolerability of long-term treatment with lovastatin in womenQ43852393
Decrease in K-ras p21 and increase in Raf1 and activated Erk 1 and 2 in murine lung tumors initiated by N-nitrosodimethylamine and promoted by 2,3,7,8-tetrachlorodibenzo-p-dioxinQ43909292
Statin use and the risk of breast and prostate cancerQ43966555
Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) ProjectQ44000674
Alterations in membrane-bound and cytoplasmic K-ras protein levels in mouse lung induced by treatment with lovastatin, cholestyramine, or niacin: effects are highly mouse strain dependentQ44054370
Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat dietQ44119079
The lovastatin-treated rodent: a new model of barrier disruption and epidermal hyperplasiaQ46057741
Mechanisms of gender-specific TCDD-induced toxicity in guinea pig adipose tissueQ46102619
Effect of cholesterol and cholestyramine feeding and of fasting on sterol synthesis in the liver, lleum, and lung of the guinea pigQ46718420
Pituitary grafts modify sex differences in liver tumor formation in the rat following initiation with diethylnitrosamine and different promotion regimensQ48337586
Differences in lung cancer risk between men and women: examination of the evidence.Q51032996
Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats.Q53452219
High lovastatin doses combined with hypercholesterolemic diet induce hepatic damage and are lethal to the CD-1 mouse.Q54091965
Influence of age and gender on the plasma profiles of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitory activity following multiple doses of lovastatin and simvastatinQ67994624
Diet-induced reduction in serum lipoproteins stimulates cell proliferation in weanling ratsQ69398694
A rat model for studying colonic cancer: Effect of cholestyramine on induced tumorsQ69638008
Variation in susceptibility to atherosclerosis among inbred strains of miceQ69805944
Inhibition of ras p21 membrane localization and modulation of protein kinase C isozyme expression during regression of chemical carcinogen-induced murine skin tumors by lovastatinQ72182671
AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent dietQ72577338
Inhibition of lung tumor cell growth in vitro and mouse lung tumor formation by lovastatinQ73040935
Chemoprevention of lung cancer by lycopeneQ73584202
SERUM CHOLESTEROL LEVELS OF INBRED RATSQ76986711
Preclinical and clinical models of lung cancer chemopreventionQ77793491
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectniacinamideQ192423
P304page(s)393-403
P577publication date2003-08-01
P1433published inBiochemical PharmacologyQ864229
P1476titleTreatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in females
P478volume66

Reverse relations

cites work (P2860)
Q35745160Elevated K-ras activity with cholestyramine and lovastatin, but not konjac mannan or niacin in lung--importance of mouse strain
Q44904792Mevalonate promotes the growth of tumors derived from human cancer cells in vivo and stimulates proliferation in vitro with enhanced cyclin-dependent kinase-2 activity
Q36765168Plasma membrane regulates Ras signaling networks

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