| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1002/ART.1780380202 |
| P698 | PubMed publication ID | 7848304 |
| P2093 | author name string | Dayer JM | |
| Arend WP | |||
| P433 | issue | 2 | |
| P921 | main subject | rheumatoid arthritis | Q187255 |
| P1104 | number of pages | 10 | |
| P304 | page(s) | 151-160 | |
| P577 | publication date | 1995-02-01 | |
| P1433 | published in | Arthritis & Rheumatology | Q4797636 |
| P1476 | title | Inhibition of the production and effects of interleukin-1 and tumor necrosis factor alpha in rheumatoid arthritis | |
| P478 | volume | 38 |
| Q79335188 | "In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology |
| Q45013659 | 15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkappaBalpha degradation in rat chondrocytes through a PPARgamma-independent pathway |
| Q43678254 | 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. |
| Q37221232 | 15-deoxy-Delta 12,14-ProstaglandinJ2 regulates dedifferentiation through peroxisome proliferator-activated receptor-gamma-dependent pathway but not COX-2 expression in articular chondrocytes |
| Q71576582 | 3rd International Symposium on the Immunotherapy of the Rheumatic Diseases. 10-14 May 1995, Cyprus. Abstracts |
| Q50085996 | A comparison of the type IX collagen levels of the intervertebral disc materials in diabetic and non-diabetic patients who treated with lumbar microdiscectomy |
| Q46390747 | A high molecular weight protein extract of Mastobranchus indicus (Mi-64) having antiarthritic activity in experimental animals |
| Q38897171 | A mechanistic review on medicinal plants used for rheumatoid arthritis in traditional Persian medicine |
| Q28469045 | A new arthritis therapy with oxidative burst inducers |
| Q40911059 | A novel (6S)-4,6-dimethyldodeca-2E,4E-dienoyl ester of phomalactone and related alpha-pyrone esters from a Phomopsis sp. with cytokine production inhibitory activity |
| Q73203136 | A patient's reaction to infliximab |
| Q43184375 | A proof-of-concept and drug-drug interaction study of pamapimod, a novel p38 MAP kinase inhibitor, with methotrexate in patients with rheumatoid arthritis |
| Q44643741 | A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis |
| Q22004148 | ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes |
| Q36835021 | AF12198, a novel low molecular weight antagonist, selectively binds the human type I interleukin (IL)-1 receptor and blocks in vivo responses to IL-1. |
| Q39232807 | Abeta-immunotherapy for Alzheimer's disease using mannan-amyloid-Beta peptide immunoconjugates. |
| Q53632460 | Absence of a clinically relevant interaction between etanercept and digoxin. |
| Q42096174 | Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage |
| Q81521829 | Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway |
| Q35552648 | Active leflunomide metabolite inhibits interleukin 1beta, tumour necrosis factor alpha, nitric oxide, and metalloproteinase-3 production in activated human synovial tissue cultures |
| Q45739253 | Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis |
| Q35554174 | Adenovirus mediated intra-articular expression of collagenase-3 (MMP-13) induces inflammatory arthritis in mice |
| Q34698382 | Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid |
| Q36670595 | Advanced imaging in rheumatoid arthritis. Part 1: synovitis |
| Q41169340 | Advances in the understanding of neuroendocrine function in rheumatic disease. |
| Q47762706 | Age-dependent decreases in serum soluble interleukin-1 receptor type I (sIL-1RI) in healthy individuals: a population study of serum sIL-1RI levels in Japanese subjects. |
| Q35547659 | Altered leucocyte trafficking and suppressed tumour necrosis factor alpha release from peripheral blood monocytes after intra-articular glucocorticoid treatment |
| Q45167042 | Ameliorative effect of ozone on cytokine production in mice injected with human rheumatoid arthritis synovial fibroblast cells |
| Q36140088 | Anti-DR5 mAb inhibits proliferation of human fibroblast-like synovial cells and reduces their cytokine secretion in vitro |
| Q42247044 | Anti-cytokine autoantibodies in autoimmune diseases |
| Q40963908 | Anti-cytokine therapy in rheumatoid arthritis |
| Q42969654 | Anti-inflammatory activities of light emitting diode irradiation on collagen-induced arthritis in mice (a secondary publication). |
| Q39103196 | Anti-inflammatory effects of Dendrobium nobile derived phenanthrenes in LPS-stimulated murine macrophages |
| Q39673920 | Anti-inflammatory effects of black rice, cyanidin-3-O-β-d-glycoside, and its metabolites, cyanidin and protocatechuic acid |
| Q39742409 | Anti-inflammatory effects of gomisin N, gomisin J, and schisandrin C isolated from the fruit of Schisandra chinensis |
| Q35552561 | Anti-inflammatory effects of leflunomide on cultured synovial macrophages from patients with rheumatoid arthritis |
| Q30780014 | Anti-inflammatory potential of alpha-linolenic acid mediated through selective COX inhibition: computational and experimental data |
| Q79273485 | Anti-tumor necrosis factor-alpha antibody treatment reduces serum CXCL16 levels in patients with rheumatoid arthritis |
| Q40845933 | Anti-tumor necrosis factor-alpha monoclonal antibody therapy for rheumatoid arthritis |
| Q36718541 | Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis |
| Q41926993 | Antimalarial drugs inhibit phospholipase A2 activation and induction of interleukin 1beta and tumor necrosis factor alpha in macrophages: implications for their mode of action in rheumatoid arthritis |
| Q39622410 | Apigenin inhibits release of inflammatory mediators by blocking the NF-κB activation pathways in the HMC-1 cells |
| Q45756724 | Arthralgias and cryoglobulinemia during protease inhibitor therapy in a patient infected with human immunodeficiency virus and hepatitis C virus |
| Q53003745 | Arthritis induced with cartilage-specific antibodiesis IL-4-dependent. |
| Q36510623 | Arthroscopic synovectomy in rheumatoid arthritis of wrist |
| Q41335748 | Articular cartilage destruction in experimental inflammatory arthritis: insulin-like growth factor-1 regulation of proteoglycan metabolism in chondrocytes |
| Q44894283 | Association of erosive hand osteoarthritis with a single nucleotide polymorphism on the gene encoding interleukin-1 beta |
| Q35551774 | Autoantibodies against interleukin 1alpha in rheumatoid arthritis: association with long term radiographic outcome. |
| Q35554200 | Autoantibodies and thrombophilia in RA: TNFalpha and TNFalpha blockers |
| Q47925939 | Balance of interleukin-1 beta and interleukin-1 receptor antagonist in human periapical lesions |
| Q41201773 | Biologic agents for the treatment of rheumatoid arthritis |
| Q35807230 | Biological agents for rheumatoid arthritis: targeting both physical function and structural damage |
| Q24816745 | Biological basis for the use of botanicals in osteoarthritis and rheumatoid arthritis: a review |
| Q40436519 | Biological therapies: a novel approach to the treatment of autoimmune disease |
| Q37323794 | Biomarkers related to aging in human populations. |
| Q43052783 | Blockade of endogenous interleukin 12 results in suppression of murine streptococcal cell wall arthritis by enhancement of interleukin 10 and interleukin 1Ra. |
| Q37360215 | Breast-cancer-associated metastasis is significantly increased in a model of autoimmune arthritis |
| Q33782282 | Building towards a consensus for the use of tumour necrosis factor blocking agents |
| Q33861973 | Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8 |
| Q43749577 | Butyrate inhibits interleukin-1-mediated nuclear factor-kappa B activation in human epithelial cells |
| Q35126948 | C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritis |
| Q37387378 | CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines |
| Q40925647 | Canine rheumatoid arthritis and inflammatory cytokines |
| Q35547065 | Cartilage and bone macromolecules in knee joint synovial fluid in rheumatoid arthritis: relation to development of knee or hip joint destruction |
| Q36564849 | Cartilage destruction by matrix degradation products |
| Q28252560 | Cellular and molecular effects of resveratrol in health and disease |
| Q41944072 | Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells |
| Q36899057 | Characterization and quantitation of NF-kappaB nuclear translocation induced by interleukin-1 and tumor necrosis factor-alpha. Development and use of a high capacity fluorescence cytometric system. |
| Q30839917 | Chemically modified ribozyme targeting TNF-alpha mRNA regulates TNF-alpha and IL-6 synthesis in synovial fibroblasts of patients with rheumatoid arthritis |
| Q59809188 | Chloroquine Protects Human Corneal Epithelial Cells from Desiccation Stress Induced Inflammation without Altering the Autophagy Flux |
| Q41946037 | Chloroquine inhibits production of TNF-alpha, IL-1beta and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modes |
| Q41630705 | Chronic inflammation in older people: recognition, consequences, and potential intervention. |
| Q35548522 | Clinical and laboratory manifestations of elderly onset psoriatic arthritis: a comparison with younger onset disease |
| Q34559795 | Clinical significance of cytokine determination in synovial fluid |
| Q34000467 | Collagen induced arthritis increases secondary metastasis in MMTV-PyV MT mouse model of mammary cancer |
| Q74209980 | Combination therapy in rheumatoid arthritis |
| Q42541303 | Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells |
| Q39765585 | Connecting the virtual world of computers to the real world of medicinal chemistry |
| Q42049241 | Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1. |
| Q46758096 | Construction of 4D-QSAR models for use in the design of novel p38-MAPK inhibitors |
| Q36961298 | Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. |
| Q43870768 | Cyclosporine differentially regulates interleukin-10, interleukin-15, and tumor necrosis factor a production by rheumatoid synoviocytes |
| Q73740084 | Cytokine expression and synovial pathology in the initiation and spontaneous resolution phases of adjuvant arthritis: interleukin-17 expression is upregulated in early disease |
| Q74330022 | Cytokine gene expression in chronic periodontitis |
| Q34830551 | Cytokines and anti-cytokine biologicals in autoimmunity: present and future |
| Q34579927 | Cytokines and anti-cytokine therapy: clinical potential for treatment of feline disease |
| Q39946607 | Cytokines and cellular interactions in inflammatory synovitis |
| Q35733792 | Cytokines in the rheumatic diseases |
| Q41666690 | DNA gene vaccination for HIV. |
| Q38335184 | DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets. |
| Q35829595 | Defective interleukin-1 receptor antagonist production is associated with resistance of acute liver graft rejection to steroid therapy |
| Q39714043 | Destructive arthritis in vaccinated interferon gamma-deficient mice challenged with Borrelia burgdorferi: modulation by tumor necrosis factor alpha |
| Q40878936 | Dietary n-3 fatty acids and therapy for rheumatoid arthritis |
| Q44663673 | Different in vitro activity of flurbiprofen and its enantiomers on human articular cartilage. |
| Q36477567 | Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects |
| Q33645324 | Disease-inducible transgene expression from a recombinant adeno-associated virus vector in a rat arthritis model |
| Q59320253 | Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1 beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting extracellular signal-regulated kinase, p38 and nuclear f |
| Q93023784 | Down-regulation of microRNA-142-3p inhibits the aggressive phenotypes of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting nuclear factor-κB signaling |
| Q33836407 | Drug-Bearing Supramolecular Filament Hydrogels as Anti-Inflammatory Agents |
| Q34495848 | Dual Effect of Chrysanthemum indicum Extract to Stimulate Osteoblast Differentiation and Inhibit Osteoclast Formation and Resorption In Vitro |
| Q86219805 | Dual inhibition of arachidonic acid pathway by mulberry leaf extract |
| Q77360241 | Dynamic changes in cytokine levels in serum and synovial fluid following filtration leukocytapheresis therapy in patients with rheumatoid arthritis |
| Q24800017 | Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1beta |
| Q84750846 | Effect and mechanism of AR-6 in experimental rheumatoid arthritis |
| Q36735154 | Effect of Bizhongxiao Decotion (BZXD) on Some Cytokines in Plasma of Rats with CII-induced Rheumatoid Arthritis |
| Q57019206 | Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1 mice |
| Q46833110 | Effect of estrogen replacement therapy on arthritis and bone mineral density in estrogen-replete rats with collagen-induced arthritis |
| Q74071848 | Effect of heparinoid on the production of tissue inhibitor of metalloproteinases (TIMP)-3 in rheumatoid synovial fibroblasts |
| Q44485466 | Effect of propolis on human cartilage and chondrocytes. |
| Q42941559 | Effect of selective COX-2 inhibitor, celecoxib on adjuvant-induced arthritis model in irradiated rats |
| Q39967125 | Effect of sildenafil citrate on interleukin-1beta-induced nitric oxide synthesis and iNOS expression in SW982 cells |
| Q39253899 | Effects of 18β-Glycyrrhetinic acid in hTNFtg mice - a model of rheumatoid arthritis |
| Q41133430 | Effects of antirheumatic agents on cytokines |
| Q40975364 | Effects of bucillamine and N-acetyl-L-cysteine on cytokine production and collagen-induced arthritis (CIA). |
| Q43053583 | Effects of induced mast cell activation on prostaglandin E and metalloproteinase production by rheumatoid synovial tissue in vitro |
| Q46619077 | Effects of interleukin-1 receptor antagonist in a slow-release hylan vehicle on rat type II collagen arthritis |
| Q78053671 | Effects of mitogen-activated protein kinase inhibitors or phosphodiesterase inhibitors on interleukin-1-induced cytokines production in synovium-derived cells |
| Q74095902 | Effects of ovariectomy and estrogen replacement therapy on arthritis and bone mineral density in rats with collagen-induced arthritis |
| Q74223406 | Effects of the second-generation leukotriene B(4) receptor antagonist, LY293111Na, on leukocyte infiltration and collagen-induced arthritis in mice |
| Q30560117 | Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data |
| Q45863651 | Electro-gene therapy of collagen-induced arthritis by using an expression plasmid for the soluble p75 tumor necrosis factor receptor-Fc fusion protein |
| Q47973486 | Elevated levels of soluble interleukin-1 receptor type II and interleukin-1 receptor antagonist in patients with chronic arthritis: correlations with markers of inflammation and joint destruction |
| Q37739800 | Ellagic acid alleviates adjuvant induced arthritis by modulation of pro- and anti-inflammatory cytokines |
| Q45861247 | Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA). |
| Q71935617 | Endogenous nitric oxide and prostaglandin E2 do not regulate the synthesis of each other in interleukin-1 beta-stimulated rat articular cartilage |
| Q36452022 | Enforced expression of roquin protein in T cells exacerbates the incidence and severity of experimental arthritis |
| Q37140765 | Etanercept Promotes Bone Formation via Suppression of Dickkopf-1 Expression in Rats with Collagen-Induced Arthritis. |
| Q80588106 | Etanercept reduces the serum levels of interleukin-23 and macrophage inflammatory protein-3 alpha in patients with rheumatoid arthritis |
| Q82455857 | Etanercept treatment reduces the serum levels of interleukin-15 and interferon-gamma inducible protein-10 in patients with rheumatoid arthritis |
| Q33544594 | Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis |
| Q36327800 | Evaluation of the Safety and Effectiveness of Add-On Tacrolimus in Patients with Rheumatoid Arthritis Who Failed to Show an Adequate Response to Biological DMARDs: The Interim Results of a Specific Drug Use-Results Survey of Tacrolimus |
| Q90263525 | Evaluation of the articular cartilage in the knees of rats with induced arthritis treated with curcumin |
| Q35905956 | Exacerbation of collagen induced arthritis by Fcγ receptor targeted collagen peptide due to enhanced inflammatory chemokine and cytokine production |
| Q45765388 | Expression of TNF alpha in arthritis caused by caprine arthritis encephalitis virus |
| Q43564115 | Expression of proteinases and inflammatory cytokines in subchondral bone regions in the destructive joint of rheumatoid arthritis |
| Q47348590 | Extracts of Arisaema rhizomatum C.E.C. Fischer attenuate inflammatory response on collagen-induced arthritis in BALB/c mice |
| Q83202778 | FK506 inhibition of gliostatin/thymidine phosphorylase production induced by tumor necrosis factor-α in rheumatoid fibroblast-like synoviocytes |
| Q35042532 | FK506 potently inhibits T cell activation induced TNF-alpha and IL-1beta production in vitro by human peripheral blood mononuclear cells |
| Q41854513 | FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis |
| Q92016330 | Feature Article: Altered morpho-functional features of bones in autoimmune disease-prone BXSB/MpJ- Yaa mice |
| Q36025268 | Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif |
| Q35855345 | Fish oils--adjuvant therapy in chronic heart failure? |
| Q35220906 | Flaxseed-a potential functional food source |
| Q26779933 | Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases |
| Q44091872 | Functional changes in rheumatoid fibroblast-like synovial cells through activation of peroxisome proliferator-activated receptor gamma-mediated signalling pathway |
| Q45885240 | Gene targeting by ribozyme against TNF-alpha mRNA inhibits autoimmune arthritis |
| Q34070348 | Gene therapy for autoimmune disorders |
| Q35122173 | Gene therapy in nonhuman primate models of human autoimmune disease. |
| Q24804867 | Gene therapy in rheumatoid arthritis: how to target joint destruction? |
| Q34385774 | Gene therapy: future therapies in osteoarthritis. |
| Q43854219 | Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model |
| Q34526939 | Genetic studies, clinical heterogeneity, and disease outcome studies in rheumatoid arthritis |
| Q28545180 | Gentiolactone, a secoiridoid dilactone from Gentiana triflora, inhibits TNF-α, iNOS and Cox-2 mRNA expression and blocks NF-κB promoter activity in murine macrophages |
| Q37582905 | Glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, inhibits the progression of group B streptococcal arthritis |
| Q49836115 | Heme oxygenase-1/biliverdin/carbon monoxide pathway downregulates hypernociception in rats by a mechanism dependent on cGMP/ATP-sensitive K+ channels |
| Q92382502 | Herbo-mineral formulation 'Ashwashila' attenuates rheumatoid arthritis symptoms in collagen-antibody-induced arthritis (CAIA) mice model |
| Q36735470 | Histomorphometric Evaluation of Cartilage Degradation using Rabbit Articular Chondrocytes Cultured in Alginate Beads - Effects of Hyaluronan |
| Q33380457 | Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism |
| Q41141957 | Human Th1 cells preferentially induce interleukin (IL)-1beta while Th2 cells induce IL-1 receptor antagonist production upon cell/cell contact with monocytes |
| Q44943174 | Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice |
| Q35605628 | Human, viral or mutant human IL-10 expressed after local adenovirus-mediated gene transfer are equally effective in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis |
| Q33578584 | IL-1 has no direct role in the IGF-1 non-responsive state during experimentally induced arthritis in mouse knee joints |
| Q45060751 | IL-1 receptor accessory protein-Ig/IL-1 receptor type II-Ig heterodimer inhibits IL-1 response more strongly than other IL-1 blocking biopharmaceutical agents |
| Q24796707 | IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis |
| Q74287010 | IL-1B and IL-1Ra gene polymorphisms and disease severity in rheumatoid arthritis: interaction with their plasma levels |
| Q35173582 | IL-1RA gene-transfected bone marrow-derived mesenchymal stem cells in APA microcapsules could alleviate rheumatoid arthritis |
| Q46431837 | IL-22+ CD4+ T cells in patients with rheumatoid arthritis |
| Q34480273 | IL-32, a proinflammatory cytokine in rheumatoid arthritis |
| Q37202023 | IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion |
| Q57003162 | IL1-beta and TNF-alpha induce changes in the nuclear polyphosphoinositide signalling system in osteoblasts similar to that occurring in patients with rheumatoid arthritis: an immunochemical and immunocytochemical study |
| Q81809220 | Immunomodulatory properties of human serum immunoglobulin A: anti-inflammatory and pro-inflammatory activities in human monocytes and peripheral blood mononuclear cells |
| Q42099571 | Implication of interleukin 18 in production of matrix metalloproteinases in articular chondrocytes in arthritis: direct effect on chondrocytes may not be pivotal |
| Q47685842 | Important immunoregulatory role of interleukin-11 in the inflammatory process in rheumatoid arthritis |
| Q35834909 | Improvement of spontaneous locomotor activity with JAK inhibition by JTE-052 in rat adjuvant-induced arthritis |
| Q40814456 | In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression |
| Q71716940 | Increased incidence of neutralizing autoantibodies against interleukin-1 alpha (IL-1 alpha) in nondestructive chronic polyarthritis |
| Q44733819 | Increased levels of IL-6, IL-1β, and TNF-α in Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency |
| Q38079456 | Inflammation and rheumatoid arthritis |
| Q81265291 | Inflammation in cystic fibrosis |
| Q44198853 | Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway |
| Q43992050 | Inhibition of interleukin-1-stimulated MAP kinases, activating protein-1 (AP-1) and nuclear factor kappa B (NF-kappa B) transcription factors down-regulates matrix metalloproteinase gene expression in articular chondrocytes |
| Q84534610 | Inhibition of pro-inflammatory mediators: role of Bacopa monniera (L.) Wettst |
| Q51615196 | Inhibitory effect of the extract of Phellodendron amurense ruprecht root on collagen-induced arthritis in mice. |
| Q38444758 | Inhibitory effects of BiRyuChe-bang on mast cell-mediated allergic reactions and inflammatory cytokines production |
| Q58781227 | Integrated Serum and Fecal Metabolomics Study of Collagen-Induced Arthritis Rats and the Therapeutic Effects of the Zushima Tablet |
| Q71971863 | Interleukin 1 beta and stromelysin (MMP3) activity of synovial fluid as possible markers of osteoarthritis in the temporomandibular joint |
| Q36370656 | Interleukin 1 receptor dependence of serum transferred arthritis can be circumvented by toll-like receptor 4 signaling |
| Q77118254 | Interleukin-1 receptor antagonist |
| Q34005163 | Interleukin-10 modulates proinflammatory cytokines in the human monocytic cell line THP-1 stimulated with Borrelia burgdorferi lipoproteins |
| Q57232110 | Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis |
| Q35675887 | Interleukin-17: the missing link between T-cell accumulation and effector cell actions in rheumatoid arthritis? |
| Q35103096 | Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction |
| Q47632515 | Interleukin-1beta and tumor necrosis factor-alpha produce distinct, time-dependent patterns of acute arthritis in the rat knee |
| Q36961144 | Interleukin-1beta-mediated inhibition of the processes of angiogenesis in cardiac microvascular endothelial cells |
| Q44060534 | Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw. |
| Q44441105 | Involvement of CD44 in induction of matrix metalloproteinases by a COOH‐terminal heparin‐binding fragment of fibronectin in human articular cartilage in culture |
| Q77627736 | Joint inflammation and cartilage destruction may occur uncoupled |
| Q37773271 | Joint injury and osteoarthritis: soluble mediators in the course and treatment of cartilage pathology |
| Q36015739 | Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production |
| Q53408911 | KPNA2 interacts with P65 to modulate catabolic events in osteoarthritis. |
| Q53462422 | Kakkalide and Its Metabolite Irisolidone Ameliorate Carrageenan-Induced Inflammation in Mice by Inhibiting NF-κB Pathway |
| Q34792751 | Kallikrein cascade and cytokines in inflamed joints |
| Q81265296 | L'inflammation dans la Mucoviscidose |
| Q28206018 | Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases |
| Q24675005 | Leflunomide: mode of action in the treatment of rheumatoid arthritis |
| Q53814762 | Levels of interleukin-1 beta can predict response to tocilizumab therapy in rheumatoid arthritis: the PETITE (predictors of effectiveness of tocilizumab therapy) study. |
| Q42997052 | Link peptide cartilage growth factor is degraded by membrane proteinases |
| Q73117771 | Long-term follow-up of the changes in circulating cytokines, soluble cytokine receptors, and white blood cell subset counts in patients with rheumatoid arthritis (RA) after monoclonal anti-TNF alpha antibody therapy |
| Q42911407 | Low activity of LSD1 elicits a pro-inflammatory gene expression profile in riboflavin-deficient human T Lymphoma Jurkat cells |
| Q82043349 | Lupeol, a triterpenoid isolated from Calotropis gigantea latex ameliorates the primary and secondary complications of FCA induced adjuvant disease in experimental rats |
| Q39746551 | Luteolin isolated from the flowers of Lonicera japonica suppresses inflammatory mediator release by blocking NF-kappaB and MAPKs activation pathways in HMC-1 cells |
| Q35094676 | MMP-Activated Fluorescence Imaging Detects Early Joint Inflammation in Collagen-Antibody-Induced Arthritis in CC-Chemokine Receptor-2-Null Mice, In-Vivo |
| Q24792173 | Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion |
| Q33578511 | Mast cells, cytokines, and metalloproteinases at the rheumatoid lesion: dual immunolocalisation studies |
| Q73892503 | Measurement of synovial tumor necrosis factor-alpha in diagnosing emergency patients with bacterial arthritis |
| Q53584799 | Measurement of the serum leptin level could assist disease activity monitoring in rheumatoid arthritis. |
| Q36618009 | Mechanisms of bone loss in rheumatoid arthritis |
| Q33756895 | Menstruation: induction by matrix metalloproteinases and inflammatory cells. |
| Q73904476 | Methotrexate suppresses nitric oxide production ex vivo in macrophages from rats with adjuvant-induced arthritis |
| Q73526256 | Methotrexate suppresses the interleukin-6 induced generation of reactive oxygen species in the synoviocytes of rheumatoid arthritis |
| Q54957861 | Mithramycin A Alleviates Osteoarthritic Cartilage Destruction by Inhibiting HIF-2α Expression. |
| Q47849220 | Modulation of angiogenic vascular endothelial growth factor by tumor necrosis factor alpha and interleukin-1 in rheumatoid arthritis |
| Q61940702 | Modulation of cytokine production by human mononuclear cells following impairment of Na,K-ATPase activity |
| Q45885757 | Modulation of proinflammatory cytokine production in tumour necrosis factor-alpha (TNF-alpha)-transgenic mice by treatment with cells engineered to secrete IL-4, IL-10 or IL-13. |
| Q34236658 | Monoclonal antibody therapy |
| Q97867216 | Mouse CD163 deficiency strongly enhances experimental collagen-induced arthritis |
| Q42048606 | Murine oncostatin M stimulates mouse synovial fibroblasts in vitro and induces inflammation and destruction in mouse joints in vivo. |
| Q45856471 | NFkappaB decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts |
| Q43512966 | Neurophysiological basis for neurogenic-mediated articular cartilage anabolism alteration |
| Q33903590 | Neutrophils: molecules, functions and pathophysiological aspects |
| Q33758853 | New treatments for rheumatoid arthritis. Available and upcoming slow-acting antirheumatic drugs |
| Q35314191 | No strong association between alleles of tumour necrosis factor alpha and interleukin-1 receptor antagonist and corneal melting associated with systemic vasculitis |
| Q77957248 | Novel cytokine release inhibitors. Part III: Truncated analogs of tripterine |
| Q43985088 | Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes |
| Q37682714 | Osteoarthritis: can anti-cytokine therapy play a role in treatment? |
| Q45881243 | Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation |
| Q33782360 | PEGylated recombinant human soluble tumour necrosis factor receptor type I (r-Hu-sTNF-RI): novel high affinity TNF receptor designed for chronic inflammatory diseases |
| Q43822295 | PPAR-gamma ligands modulate effects of LPS in stimulated rat synovial fibroblasts |
| Q37362252 | Peptide-based Biopolymers in Biomedicine and Biotechnology |
| Q24791076 | Physiologic role of interleukin-1 receptor antagonist |
| Q40977170 | Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB. |
| Q42547692 | Positive correlation between levels of IL-1 or IL-2 and 1,25(OH)2D/25-OH-D ratio in synovial fluid of patients with rheumatoid arthritis |
| Q38194211 | Positron emission tomography/computed tomography imaging and rheumatoid arthritis |
| Q51183072 | Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis. |
| Q46917160 | Potassium humate inhibits complement activation and the production of inflammatory cytokines in vitro |
| Q35555622 | Pregnancy in patients with rheumatic disease: anti-inflammatory cytokines increase in pregnancy and decrease post partum |
| Q40861531 | Pro- and anti-inflammatory cytokines in rheumatoid arthritis |
| Q43524051 | Progress in development of herpes simplex virus gene vectors for treatment of rheumatoid arthritis |
| Q34118568 | Progress in the use of biochemical and biological markers for evaluation of rheumatoid arthritis. |
| Q40968027 | Prospects of immunotherapy for rheumatoid arthritis |
| Q33899147 | Prostaglandin E(2) binding peptide screened by phage displaying: a new therapeutic strategy in rheumatoid arthritis |
| Q24792053 | Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis |
| Q45864537 | Protection against collagen-induced arthritis by intramuscular gene therapy with an expression plasmid for the interleukin-1 receptor antagonist |
| Q28298994 | Protective Effect of Ethanolic Extract of Seeds of Moringa oleifera Lam. Against Inflammation Associated with Development of Arthritis in Rats |
| Q28570898 | RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies |
| Q90390249 | Rapamycin protects chondrocytes against IL-18-induced apoptosis and ameliorates rat osteoarthritis |
| Q77368725 | Recombinant chimeric OKT3/IgM antibodies for immune suppression: evaluation in a human CD3 transgenic mouse model |
| Q50559887 | Red wine may be used in the therapy of myocarditis |
| Q80865349 | Reduction of urinary levels of pyridinoline and deoxypyridinoline and serum levels of soluble receptor activator of NF-kappaB ligand by etanercept in patients with rheumatoid arthritis |
| Q79808629 | Regulation of bone lysis in inflammatory diseases |
| Q42163509 | Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration |
| Q39314238 | Regulation of inflammatory response in human chondrocytes by lentiviral mediated RNA interference against S100A10. |
| Q43683238 | Regulation of tumor necrosis factor alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts by the protein kinase Akt. |
| Q34123507 | Regulatory role of interleukin-10 in experimental group B streptococcal arthritis |
| Q89107388 | Relative expression and correlation of tumor necrosis factor-α, interferon-γ, and interleukin-17 in the rheumatoid synovium |
| Q71046923 | Rheumatoid arthritis |
| Q34275998 | Rheumatoid arthritis. From bench to bedside |
| Q34706975 | Rheumatoid arthritis: developing pharmacological therapies |
| Q34497135 | Rodent preclinical models for developing novel antiarthritic molecules: comparative biology and preferred methods for evaluating efficacy |
| Q34071325 | Role of interleukin 1 and interleukin 1 receptor antagonist in the mediation of rheumatoid arthritis |
| Q44041992 | Role of macrophages in experimental group B streptococcal arthritis |
| Q34001731 | Role of tumor necrosis factor alpha, interleukin-1beta, and interleukin-6 in a mouse model of group B streptococcal arthritis |
| Q70911070 | Role of tumor necrosis factor-alpha in the regulation of activated synovial T cell growth: down-regulation of synovial T cells in rheumatoid arthritis patients |
| Q58831756 | Role of tumor necrosis factor-α and platelet-activating factor in neoangiogenesis induced by synovial fluids of patients with rheumatoid arthritis |
| Q33782333 | Role of tumour necrosis factor alpha in experimental arthritis: separate activity of interleukin 1beta in chronicity and cartilage destruction |
| Q36028645 | Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. |
| Q58805793 | Sex Differences in Sleep Duration among Older Adults with Self-Reported Diagnosis of Arthritis: National Health and Nutrition Examination Survey, 2009-2012 |
| Q43870766 | Sexual dimorphism in innate immunity |
| Q33782305 | Signal transduction by tumour necrosis factor and tumour necrosis factor related ligands and their receptors |
| Q39621544 | Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor α. |
| Q77317912 | Soluble IL-1 receptor type I binds to human dermal fibroblasts and induces calcium flux |
| Q35549487 | Spontaneous and cytokine regulated c-fos gene expression in rheumatoid synovial cells: resistance to cytokine stimulation when the c-fos gene is overexpressed |
| Q53269765 | Steroid treatment can inhibit nuclear localization of members of the NF-κB pathway in human disc cells stimulated with TNF-α. |
| Q33771505 | Stress system response and rheumatoid arthritis: a multilevel approach |
| Q45864343 | Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy |
| Q33402894 | Suppression of complete Freund's adjuvant-induced adjuvant arthritis by cobratoxin |
| Q30453928 | Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA. |
| Q44301851 | Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid |
| Q54536252 | Suppressive effect of an orally active MEK1/2 inhibitor in two different animal models for rheumatoid arthritis: a comparison with leflunomide. |
| Q38977054 | Suppressive effects of britanin, a sesquiterpene compound isolated from Inulae flos, on mast cell-mediated inflammatory responses |
| Q40718956 | Syngeneic fibroblasts transfected with a plasmid encoding interleukin-4 as non-viral vectors for anti-inflammatory gene therapy in collagen-induced arthritis |
| Q74165395 | Synovial fluid cytokines and proteinases as markers of temporomandibular joint disease |
| Q37380147 | Synovium as a source of increased amino-terminal parathyroid hormone-related protein expression in rheumatoid arthritis. A possible role for locally produced parathyroid hormone-related protein in the pathogenesis of rheumatoid arthritis |
| Q34895962 | THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis |
| Q35553022 | TNF receptor gene therapy results in suppression of IgG2a anticollagen antibody in collagen induced arthritis |
| Q74404685 | Tenidap decreases IL-8 and monocyte chemotactic peptide-1 (MCP-1) mRNA expression in the synovial tissue of rabbits with antigen arthritis and in cultured synovial cells |
| Q54406138 | Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin‐17A production |
| Q37686348 | Th17 cytokines and arthritis |
| Q38068964 | Th22 and related cytokines in inflammatory and autoimmune diseases |
| Q37850717 | Th22 in inflammatory and autoimmune disease: prospects for therapeutic intervention |
| Q45928255 | Thalidomide affects the skeletal system of ovariectomized rats. |
| Q43596294 | Thalidomide revisited: pharmacology and clinical applications |
| Q37974744 | Thalidomide: an old drug with new action |
| Q33899122 | Thalidomide: current and potential clinical applications |
| Q35997105 | The Clinical Significance of Interleukin-1 Receptor Antagonist +2018 Polymorphism in Rheumatoid Arthritis |
| Q92545462 | The GSK‑3β/β‑catenin signaling pathway is involved in HMGB1‑induced chondrocyte apoptosis and cartilage matrix degradation |
| Q26773127 | The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer Diseases |
| Q36245861 | The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes. |
| Q80522537 | The association of DRB1*04 share epitope alleles and tumor necrosis factor-alpha gene polymorphism (-863) with susceptibility to rheumatoid arthritis in Thai |
| Q74425062 | The dual role of interferon-gamma in experimental Staphylococcus aureus septicaemia versus arthritis |
| Q43494262 | The evolving systemic and local biomarker milieu at different stages of disease progression in rat adjuvant-induced arthritis |
| Q46531028 | The influence of irradiation on the potential chondroprotective effect of aqueous extract of propolis in rats |
| Q41558341 | The mechanisms of action of disease-modifying antirheumatic drugs: a review with emphasis on macrophage signal transduction and the induction of proinflammatory cytokines |
| Q30887007 | The oxazolidinone derivative locostatin induces cytokine appeasement. |
| Q34122715 | The pathogenesis and prevention of joint damage in rheumatoid arthritis: advances from synovial biopsy and tissue analysis |
| Q36072707 | The potential of signal transduction inhibitors for the treatment of arthritis: Is it all just JNK? |
| Q33894450 | The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models |
| Q33535424 | The role of gene therapy. Fact or fiction? |
| Q36366835 | The role of gp130-mediated signals in osteoclast development: regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures. |
| Q43263312 | The role of lipopolysaccharide injected systemically in the reactivation of collagen-induced arthritis in mice |
| Q41996003 | The snake venom metalloproteinase BaP1 induces joint hypernociception through TNF-alpha and PGE2-dependent mechanisms |
| Q24805297 | The stressed synovium |
| Q35164732 | The therapeutic potential of TNF-alpha blockade in rheumatoid arthritis |
| Q35688168 | The use of TNF-alpha blocking agents in rheumatoid arthritis: an overview |
| Q36916918 | The use of TNF-alpha blocking agents in rheumatoid arthritis: an update |
| Q33976382 | Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial |
| Q37129557 | Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits. |
| Q34108776 | Therapy of rheumatoid arthritis: new developments and trends |
| Q77598591 | Thienopyrimidine derivatives prevent cartilage destruction in articular disease |
| Q77776111 | Thioredoxin and mechanism of inflammatory response |
| Q42452643 | Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes |
| Q73502940 | Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein |
| Q45890242 | Treatment of rheumatoid arthritis with IL-1 inhibitors |
| Q33782376 | Treatment of rheumatoid arthritis with interleukin 1 receptor antagonist |
| Q83299921 | Treatment with anti-TNF-alpha antibody infliximab reduces serum IL-15 levels in patients with rheumatoid arthritis |
| Q43760473 | Triptolide, a novel diterpenoid triepoxide from Tripterygium wilfordii Hook. f., suppresses the production and gene expression of pro-matrix metalloproteinases 1 and 3 and augments those of tissue inhibitors of metalloproteinases 1 and 2 in human sy |
| Q85118797 | Tumor Necrosis Factor-α Up-Regulates the Expression of β1,4-Galactosyltransferase-I in Human Fibroblast-like Synoviocytes |
| Q40904867 | Tumor necrosis factor alpha promotes the expression of stem cell factor in synovial fibroblasts and their capacity to induce mast cell chemotaxis |
| Q43937881 | Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin |
| Q41482071 | Tumor necrosis factor receptor p55 controls the severity of arthritis in experimental Yersinia enterocolitica infection. |
| Q43829167 | Tumor necrosis factor-alpha negatively regulates airway hyperresponsiveness through gamma-delta T cells |
| Q35554897 | Tumour necrosis factor receptor gene therapy affects cellular immune responses in collagen induced arthritis in mice. |
| Q79246564 | Tumour necrosis factor-alpha and apoptosis in the rat temporomandibular joint |
| Q33822653 | Type 1 regulatory T cells specific for collagen type II as an efficient cell-based therapy in arthritis |
| Q77713039 | Update on treatment of rheumatoid arthritis |
| Q79264738 | Vaccination against IL-17 suppresses autoimmune arthritis and encephalomyelitis |
| Q54392547 | Zonal differences in nitric oxide synthesis by bovine chondrocytes exposed to interleukin-1. |
| Q53855814 | [Biologicals in treatment of rheumatoid arthritis and other inflammatory arthropathies]. |
| Q81772562 | [Echocardiographic functional analysis of patients with rheumatoid arthritis and collagen diseases] |
| Q73370072 | [Rheumatoid arthritis: new molecular and cellular aspects] |
| Q37192084 | α-Tocopheryl Succinate Inhibits Osteoclast Formation by Suppressing Receptor Activator of Nuclear Factor-kappaB Ligand (RANKL) Expression and Bone Resorption |
| Q54397145 | β1,4-galactosyltransferase-I in synovial tissue of collagen-induced rat model of rheumatoid arthritis. |
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