Reovirus nonstructural protein mu NS recruits viral core surface proteins and entering core particles to factory-like inclusions

scientific article published on February 2004

Reovirus nonstructural protein mu NS recruits viral core surface proteins and entering core particles to factory-like inclusions is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.78.4.1882-1892.2004
P932PMC publication ID369481
P698PubMed publication ID14747553

P50authorCathy L. MillerQ38319404
P2093author name stringJohn S L Parker
Max L Nibert
Teresa J Broering
Jonghwa Kim
Jason B Dinoso
Caroline D S Piggott
P2860cites workStructure of the reovirus core at 3.6 A resolutionQ27622391
RNA synthesis in a cage--structural studies of reovirus polymerase lambda3Q27640090
Internal/structures containing transcriptase-related proteins in top component particles of mammalian orthoreovirusQ28272793
Aggresomes: a cellular response to misfolded proteinsQ28292275
The M1 gene is associated with differences in the temperature optimum of the transcriptase activity in reovirus core particlesQ28775716
Aggresomes, inclusion bodies and protein aggregationQ29615253
RNA polymerase activity in purified reovirusesQ30532564
Reovirus mu2 protein determines strain-specific differences in the rate of viral inclusion formation in L929 cellsQ31774257
Reovirus sigmaNS protein is required for nucleation of viral assembly complexes and formation of viral inclusions.Q33836647
Reovirus core protein mu2 determines the filamentous morphology of viral inclusion bodies by interacting with and stabilizing microtubules.Q34122036
RNA interference: antiviral defense and genetic toolQ34711481
Reovirus σNS and μNS Proteins Form Cytoplasmic Inclusion Structures in the Absence of Viral InfectionQ34976721
Small reovirus particle composed solely of sigma NS with specificity for binding different nucleic acids.Q35239662
The penetration of reovirus RNA and initiation of its genetic function in L-strain fibroblastsQ36189245
Immunofluorescent localization of double-stranded RNA in reovirus-infected cellsQ69909642
The interaction of mammalian reoviruses with the cytoskeleton of monkey kidney CV-1 cellsQ70679241
Characterization of anti-reovirus immunoglobulins secreted by cloned hybridoma cell linesQ70891866
Studies on the intracellular synthesis of reovirus-specified proteinsQ71554391
Reovirus: RNA polymerase activity in purified virionsQ72299931
Characterization and structural localization of the reovirus lambda 3 proteinQ72484237
Mammalian reovirus L2 gene and lambda2 core spike protein sequences and whole-genome comparisons of reoviruses type 1 Lang, type 2 Jones, and type 3 DearingQ74449255
Structure of mammalian orthoreovirus particlesQ74585498
Sigma 1 protein of mammalian reoviruses extends from the surfaces of viral particlesQ36826294
Monoclonal antibodies to reovirus reveal structure/function relationships between capsid proteins and genetics of susceptibility to antibody actionQ36828429
Activation and characterization of the reovirus transcriptase: genetic analysisQ36936630
Reovirus protein sigmaNS binds in multiple copies to single-stranded RNA and shares properties with single-stranded DNA binding proteinsQ38311437
Studies on the structure of reovirus cores: Selective removal of polypeptide λ2Q39085390
In vitro recoating of reovirus cores with baculovirus-expressed outer-capsid proteins mu1 and sigma3.Q39550452
Reovirus nonstructural protein muNS binds to core particles but does not inhibit their transcription and capping activitiesQ39591375
The hydrophilic amino-terminal arm of reovirus core shell protein lambda1 is dispensable for particle assemblyQ39686182
Reovirus sigma NS protein localizes to inclusions through an association requiring the mu NS amino terminusQ39741994
Mammalian reovirus nonstructural protein microNS forms large inclusions and colocalizes with reovirus microtubule-associated protein micro2 in transfected cellsQ39753074
Reovirus guanylyltransferase is L2 gene product lambda 2.Q40131290
The structure and function of the reovirus genomeQ40304672
The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry.Q40344603
Aggresomes resemble sites specialized for virus assemblyQ40603651
Transcription In Vitro by Reovirus-Associated Ribonucleic Acid-Dependent PolymeraseQ40709706
Reoviruses and the interferon system.Q41040736
Amino terminus of reovirus nonstructural protein sigma NS is important for ssRNA binding and nucleoprotein complex formationQ41068675
Generation of reovirus core-like particles in cells infected with hybrid vaccinia viruses that express genome segments L1, L2, L3, and S2.Q41511090
Reovirus genome segment assortment into progeny genomes studied by the use of monoclonal antibodies directed against reovirus proteinsQ41631747
Assembly of the reovirus outer capsid requires mu 1/sigma 3 interactions which are prevented by misfolded sigma 3 protein in temperature-sensitive mutant tsG453.Q41633883
Mammalian reovirus M3 gene sequences and conservation of coiled-coil motifs near the carboxyl terminus of the microNS proteinQ42612836
Cytochemical, fluorescent-antibody and electron microscopic studies on the growth of reovirus (ECHO 10) in tissue cultureQ43500409
Reovirus morphogenesis. Corelike particles in cells infected at 39 degrees with wild-type reovirus and temperature-sensitive mutants of groups B and G.Q43533239
Reovirus protein lambda 3 is a poly(C)-dependent poly(G) polymeraseQ43576087
Mutational analysis of a mammalian reovirus mRNA capping enzymeQ43897367
A positive-strand RNA virus replication complex parallels form and function of retrovirus capsidsQ45733045
The sequences of reovirus serotype 3 genome segments M1 and M3 encoding the minor protein mu 2 and the major nonstructural protein mu NS, respectivelyQ48300735
Binding site for S-adenosyl-L-methionine in a central region of mammalian reovirus lambda2 protein. Evidence for activities in mRNA cap methylation.Q52565526
Multiple forms of SS → DS RNA polymerase activity in reovirus-infected cellsQ53847255
Characterization of transcriptase and replicase particles isolated from reovirus-infected cellsQ67345969
Reovirus-coded polypeptides in infected cells: Isolation of two native monomeric polypeptides with affinity for single-stranded and double-stranded RNA, respectivelyQ67446847
Polypeptide components of virions, top component and cores of reovirus type 3Q68603064
The induction of interferon by temperature-sensitive mutants of reovirus, UV-irradiated reovirus, and subviral reovirus particlesQ68654795
Temperature-sensitive mutants of reovirus. I. Patterns of gene expression by mutants of groups C, D, and EQ69452858
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectReovirusQ69812835
P304page(s)1882-1892
P577publication date2004-02-01
P1433published inJournal of VirologyQ1251128
P1476titleReovirus nonstructural protein mu NS recruits viral core surface proteins and entering core particles to factory-like inclusions
P478volume78

Reverse relations

cites work (P2860)
Q34006244A guide to viral inclusions, membrane rearrangements, factories, and viroplasm produced during virus replication
Q39046931Amino acids 78 and 79 of Mammalian Orthoreovirus protein µNS are necessary for stress granule localization, core protein λ2 interaction, and de novo virus replication.
Q61447732Antiviral Responses and Biological Concequences of Infection in Salmonid Erythrocytes
Q35621405Aquareovirus NS80 Initiates Efficient Viral Replication by Retaining Core Proteins within Replication-Associated Viral Inclusion Bodies
Q34592621Aquareovirus NS80 recruits viral proteins to its inclusions, and its C-terminal domain is the primary driving force for viral inclusion formation
Q36863582Aquareovirus protein VP6 colocalizes with NS80 protein in infected and transfected cells
Q40338701Avian reovirus microNS protein forms homo-oligomeric inclusions in a microtubule-independent fashion, which involves specific regions of its C-terminal domain
Q40162412Avian reovirus temperature-sensitive mutant tsA12 has a lesion in major core protein sigmaA and is defective in assembly
Q40429759Carboxyl-proximal regions of reovirus nonstructural protein muNS necessary and sufficient for forming factory-like inclusions
Q40055051Characterization of a replicating mammalian orthoreovirus with tetracysteine tagged μNS for live cell visualization of viral factories
Q36077953Characterization of grass carp reovirus minor core protein VP4.
Q39678562Characterization of the nonstructural protein NS80 of grass carp reovirus
Q58618419DNA vaccine expressing the non-structural proteins of Piscine orthoreovirus delay the kinetics of PRV infection and induces moderate protection against heart -and skeletal muscle inflammation in Atlantic salmon (Salmo salar)
Q37713862Development of continuous cell culture of brown planthopper to trace the early infection process of oryzaviruses in insect vector cells
Q39997322Formation of the factory matrix is an important, though not a sufficient function of nonstructural protein mu NS during reovirus infection
Q64068315Function, Architecture, and Biogenesis of Reovirus Replication Neoorganelles
Q35003905Functional investigation of grass carp reovirus nonstructural protein NS80.
Q30356543Gene-specific inhibition of reovirus replication by RNA interference.
Q35857383Guanidine hydrochloride inhibits mammalian orthoreovirus growth by reversibly blocking the synthesis of double-stranded RNA.
Q92989195How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?
Q38765667Identification and characterization of two cleavage fragments from the Aquareovirus nonstructural protein NS80.
Q37127878Identification of functional domains in reovirus replication proteins muNS and mu2.
Q39991940Increased ubiquitination and other covariant phenotypes attributed to a strain- and temperature-dependent defect of reovirus core protein mu2.
Q40381336Interaction of Mal de Río Cuarto virus (Fijivirus genus) proteins and identification of putative factors determining viroplasm formation and decay.
Q40194299Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8.
Q33558325Localization of mammalian orthoreovirus proteins to cytoplasmic factory-like structures via nonoverlapping regions of microNS
Q40088765Mammalian Orthoreovirus Factories Modulate Stress Granule Protein Localization by Interaction with G3BP1.
Q98509945Mammalian orthoreovirus core protein μ2 reorganizes host microtubule-organizing center components
Q41844888Mammalian orthoreovirus particles induce and are recruited into stress granules at early times postinfection
Q39642017Molecular characterization of nonstructural protein NS38 of grass carp reovirus
Q47555849Non-structural protein σ1s is required for optimal reovirus protein expression
Q34721254Nonstructural protein NS80 is crucial in recruiting viral components to form aquareoviral factories
Q41095710Nonstructural protein Pns12 of rice dwarf virus is a principal regulator for viral replication and infection in its insect vector
Q27314173Protein expression redirects vesicular stomatitis virus RNA synthesis to cytoplasmic inclusions
Q40530759Putative autocleavage of outer capsid protein micro1, allowing release of myristoylated peptide micro1N during particle uncoating, is critical for cell entry by reovirus.
Q38918571Recovery of infectious bluetongue virus from RNA.
Q30536173Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking
Q54209646Reovirus Nonstructural Protein σNS Acts as an RNA-Stability Factor Promoting Viral Genome Replication.
Q37621639Reovirus forms neo-organelles for progeny particle assembly within reorganized cell membranes.
Q40052207Reovirus inhibits interferon production by sequestering IRF3 into viral factories.
Q39307482Reovirus replication protein μ2 influences cell tropism by promoting particle assembly within viral inclusions
Q36397535Reovirus uses multiple endocytic pathways for cell entry.
Q56395824Reovirus σNS and μNS Proteins Remodel the Endoplasmic Reticulum to Build Replication Neo-Organelles
Q37945206Role of lipids on entry and exit of bluetongue virus, a complex non-enveloped virus
Q34228672Rotavirus glycoprotein NSP4 is a modulator of viral transcription in the infected cell.
Q34905720Sequence analysis of the genome of piscine orthoreovirus (PRV) associated with heart and skeletal muscle inflammation (HSMI) in Atlantic salmon (Salmo salar).
Q37441928Sequences of avian reovirus M1, M2 and M3 genes and predicted structure/function of the encoded mu proteins
Q40142474Silencing and complementation of reovirus core protein mu2: functional correlations with mu2-microtubule association and differences between virus- and plasmid-derived mu2.
Q35922315The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication
Q39441933The cellular chaperone hsc70 is specifically recruited to reovirus viral factories independently of its chaperone function.
Q49894263The dynamics of both filamentous and globular mammalian reovirus viral factories rely on the microtubule network
Q38805732The non-structural protein μNS of piscine orthoreovirus (PRV) forms viral factory-like structures
Q39318008Viral hijacking of host caspases: an emerging category of pathogen-host interactions.
Q45406516Virus-derived platforms for visualizing protein associations inside cells

Search more.