| P50 | author | Ronald T. Raines | Q11205655 |
| | Nadia J Kershaw | Q54151144 |
| | Kelly L. Rogers | Q55180008 |
| | James W Checco | Q57149290 |
| | David G Belair | Q57149318 |
| | Walter D Fairlie | Q57417975 |
| | Samuel H. Gellman | Q85544063 |
| | Anne Pettikiriarachchi | Q114428972 |
| | Chelcie H Eller | Q125309084 |
| | Brian J. Smith | Q40337710 |
| | Erinna Lee | Q47713751 |
| P2093 | author name string | William L Murphy | |
| | Julia L Wilson | |
| | Geoffrey A Eddinger | |
| | Marco Evangelista | |
| | Nerida J Sleebs | |
| P2860 | cites work | Highly Efficient Synthesis of Covalently Cross-Linked Peptide Helices by Ring-Closing Metathesis | Q56874875 |
| | Further Insights into the Effects of Pre-organizing the BimBH3 Helix | Q56983645 |
| | Synthesis, biological activity and conformational analysis of cyclic GRF analogs | Q67249874 |
| | Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide | Q79733375 |
| | Calculation of protein extinction coefficients from amino acid sequence data | Q27861073 |
| | A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time | Q28253043 |
| | Hydrocarbon-stapled peptides: principles, practice, and progress | Q28542025 |
| | Reaching for high-hanging fruit in drug discovery at protein-protein interfaces | Q29547258 |
| | An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 |
| | BCL-2 family members and the mitochondria in apoptosis | Q29614427 |
| | A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers. | Q30466831 |
| | Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancer | Q33400716 |
| | Bridged beta(3)-peptide inhibitors of p53-hDM2 complexation: correlation between affinity and cell permeability | Q33782756 |
| | Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic | Q34069846 |
| | Small-molecule inhibitors of protein-protein interactions: progressing toward the reality | Q34263719 |
| | A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo | Q34282783 |
| | Enhanced metabolic stability and protein-binding properties of artificial alpha helices derived from a hydrogen-bond surrogate: application to Bcl-xL. | Q34313929 |
| | Backbone modification of a polypeptide drug alters duration of action in vivo | Q34385531 |
| | Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia | Q34392488 |
| | BCL-2 family antagonists for cancer therapy | Q34891196 |
| | Targeting diverse protein-protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold | Q35484964 |
| | The Bcl-2 family: roles in cell survival and oncogenesis. | Q35591695 |
| | Novel structures of self-associating stapled peptides | Q35835917 |
| | Assessment of helical interfaces in protein-protein interactions | Q36074876 |
| | Nucleation effects in peptide foldamers | Q36103469 |
| | Development of α-helical calpain probes by mimicking a natural protein-protein interaction | Q36469004 |
| | Synthetic therapeutic peptides: science and market | Q37625355 |
| | Peptide stapling techniques based on different macrocyclisation chemistries | Q38246909 |
| | Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics. | Q38253734 |
| | Hydrocarbon stapled peptides as modulators of biological function | Q38387394 |
| | Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia | Q39405994 |
| | Development of potent glucagon-like peptide-1 agonists with high enzyme stability via introduction of multiple lactam bridges | Q39670832 |
| | Influence of macrocyclization on allosteric, juxtamembrane-derived, stapled peptide inhibitors of the epidermal growth factor receptor (EGFR). | Q41826289 |
| | Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling. | Q41916714 |
| | α-Helix mimicry with α/β-peptides | Q41965412 |
| | Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains. | Q42146826 |
| | Distinct BimBH3 (BimSAHB) stapled peptides for structural and cellular studies. | Q42788323 |
| | Ring-closing metathesis of olefinic peptides: design, synthesis, and structural characterization of macrocyclic helical peptides. | Q46228530 |
| | Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 |
| | Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins | Q24302494 |
| | A stapled BID BH3 helix directly binds and activates BAX | Q24307663 |
| | Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix | Q24537504 |
| | Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitors | Q24630804 |
| | Solution structure of the antiapoptotic protein bcl-2 | Q27630598 |
| | Helix bundle quaternary structure from alpha/beta-peptide foldamers | Q27644076 |
| | Structural insights into the degradation of Mcl-1 induced by BH3 domains | Q27644256 |
| | Structural plasticity underpins promiscuous binding of the prosurvival protein A1 | Q27650558 |
| | Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly | Q27650994 |
| | High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL | Q27653863 |
| | Structural and biological mimicry of protein surface recognition by / -peptide foldamers | Q27657158 |
| | Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX | Q27665695 |
| | Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design | Q27670755 |
| | Crystal structure of a BCL-W domain-swapped dimer: implications for the function of BCL-2 family proteins | Q27675059 |
| | Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain | Q27675317 |
| | Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins | Q27679468 |
| | Stabilizing the pro-apoptotic BimBH3 helix (BimSAHB) does not necessarily enhance affinity or biological activity | Q27683432 |
| | Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis | Q27734734 |
| | XDS | Q27860472 |
| | Coot: model-building tools for molecular graphics | Q27860505 |
| | Likelihood-enhanced fast translation functions | Q27860634 |
| | Likelihood-enhanced fast rotation functions | Q27860684 |
| | Pushing the boundaries of molecular replacement with maximum likelihood | Q27860922 |
| | PHENIX: building new software for automated crystallographic structure determination | Q27861044 |
| P433 | issue | 35 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | protein-protein interaction | Q896177 |
| P304 | page(s) | 11365-11375 | |
| P577 | publication date | 2015-08-28 | |
| P1433 | published in | Journal of the American Chemical Society | Q898902 |
| P1476 | title | α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells | |
| P478 | volume | 137 | |