Overexpression of leukocyte marker CD43 causes activation of the tumor suppressor proteins p53 and ARF.

scientific article published on April 2004

Overexpression of leukocyte marker CD43 causes activation of the tumor suppressor proteins p53 and ARF. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1034603304
P356DOI10.1038/SJ.ONC.1207359
P698PubMed publication ID14676827
P5875ResearchGate publication ID8958066

P2093author name stringToivo Maimets
Sirle Laos
Lilian Kadaja
P2860cites workMechanisms of Cr(VI) induced p53 activation: the role of phosphorylation, mdm2 and ERKQ23922086
Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndromeQ24303591
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathwaysQ24321528
A genetic model for colorectal tumorigenesisQ27860582
p53, the cellular gatekeeper for growth and divisionQ27860990
WAF1, a potential mediator of p53 tumor suppressionQ27861121
CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytesQ28141639
Tumor suppression by Ink4a-Arf: progress and puzzlesQ28207959
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53Q28266637
T cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activationQ28272069
Cancer cell cyclesQ29547756
Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylationQ29618286
The ARF/p53 pathwayQ33840421
Disregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survivalQ34786830
Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndromeQ36348858
Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferationQ36352548
CD43 interferes with T-lymphocyte adhesionQ37039323
Adhesion via CD43 induces Syk activation and cell proliferation in TF-1 cellsQ40775700
Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatinQ40859019
The cat and mouse games that genes, viruses, and cells playQ41367391
Keeping an old friend under control: regulation of p53 stabilityQ47786180
p14ARF links the tumour suppressors RB and p53.Q55067966
p19ARF links the tumour suppressor p53 to RasQ57562848
Colon adenoma and cancer cells aberrantly express the leukocyte-associated sialoglycoprotein CD43Q73703161
Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerizationQ77540498
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectoverexpressionQ61643320
P304page(s)2523-2530
P577publication date2004-04-01
P1433published inOncogeneQ1568657
P1476titleOverexpression of leukocyte marker CD43 causes activation of the tumor suppressor proteins p53 and ARF.
P478volume23

Reverse relations

cites work (P2860)
Q39411149An alternative mode of CD43 signal transduction activates pro-survival pathways of T lymphocytes.
Q40076969CD43 promotes cell growth and helps to evade FAS-mediated apoptosis in non-hematopoietic cancer cells lacking the tumor suppressors p53 or ARF.
Q35049278CD43 promotes cells transformation by preventing merlin-mediated contact inhibition of growth
Q35430828Cladribine and Fludarabine Nucleoside Change the Levels of CD Antigens on B-Lymphoproliferative Disorders
Q35207723Common polymorphisms in the CD43 gene region are associated with tuberculosis disease and mortality

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