| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M308620200 |
| P698 | PubMed publication ID | 14660668 |
| P2093 | author name string | Satoshi Kimura | |
| Koichi Hirai | |||
| Kunihisa Tsukada | |||
| Miki Kawada | |||
| Yohtaroh Takagaki | |||
| Yasuo Ota | |||
| Shintaro Yanagimoto | |||
| Shu Okugawa | |||
| Takatoshi Kitazawa | |||
| Kuniko Nakayama | |||
| P2860 | cites work | IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family | Q22010176 |
| IRAK-M is a negative regulator of Toll-like receptor signaling | Q24302640 | ||
| IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling | Q24309107 | ||
| IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase | Q24534145 | ||
| Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells | Q28209023 | ||
| The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults | Q28289939 | ||
| The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein | Q28307210 | ||
| Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components | Q28511151 | ||
| MyD88: an adapter that recruits IRAK to the IL-1 receptor complex | Q28611795 | ||
| Innate immunity: the virtues of a nonclonal system of recognition | Q29614428 | ||
| MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways | Q29616209 | ||
| Tolerance to endotoxin-induced expression of the interleukin-1 beta gene in blood neutrophils of humans with the sepsis syndrome | Q33892692 | ||
| Dysregulation of in vitro cytokine production by monocytes during sepsis | Q34211246 | ||
| Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members | Q35079256 | ||
| Gram-negative sepsis: a dilemma of modern medicine | Q36639504 | ||
| Janus kinase 2 is involved in lipopolysaccharide-induced activation of macrophages | Q40657235 | ||
| Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4. | Q40787830 | ||
| Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells | Q40879729 | ||
| Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression | Q42488328 | ||
| NF-kappaB expression in mononuclear cells of patients with sepsis resembles that observed in lipopolysaccharide tolerance | Q43511338 | ||
| Tolerance to pyrogens | Q46262544 | ||
| Lipopolysaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: distinct alterations in IL-1 receptor-associated kinase. | Q52546316 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6629-6634 | |
| P577 | publication date | 2003-12-04 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Involvement of IRAK-M in peptidoglycan-induced tolerance in macrophages | |
| P478 | volume | 279 |
| Q34258676 | A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages |
| Q52605329 | A study of the key genes and inflammatory signaling pathways involved in HLA-B27-associated acute anterior uveitis families. |
| Q24317005 | A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation |
| Q34669410 | Activation of human macrophages by bacterial components relieves the restriction on replication of an interferon-inducing parainfluenza virus 5 (PIV5) P/V mutant |
| Q38675945 | Altered Toll-like receptor 2-mediated endotoxin tolerance is related to diminished interferon beta production. |
| Q28305636 | Association of interleukin-1 receptor-associated kinase M (IRAK-M) and inflammatory bowel diseases |
| Q36288640 | Chronic stimulation of Nod2 mediates tolerance to bacterial products |
| Q36678496 | CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases |
| Q42148867 | Differential Expression of Th1- and Th2- Type Cytokines in Peripheral Blood Mononuclear Cells of Murrah Buffalo (Bubalus Bubalis) on TLR2 Induction by B. Subtilis Peptidoglycan. |
| Q24300680 | Differential regulation and role of interleukin-1 receptor associated kinase-M in innate immunity signaling |
| Q40734636 | Differential roles of Toll-like receptors 2 and 4 in in vitro responses of macrophages to Legionella pneumophila |
| Q54525610 | Down-regulation of toll-like receptor 4 in the granulation tissues of postoperative mastoid cavities with otorrhea. |
| Q24304456 | Early and preferential induction of IL-1 receptor-associated kinase-M in THP-1 cells by LPS derived from Porphyromonas gingivalis |
| Q36479398 | Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination? |
| Q35023017 | Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M. |
| Q33618905 | IRAK-M regulates chromatin remodeling in lung macrophages during experimental sepsis |
| Q38856948 | IRAK-M regulates the inhibition of TLR-mediated macrophage immune response during late in vitro Leishmania donovani infection |
| Q37851354 | IRAK-M regulation and function in host defense and immune homeostasis |
| Q48136593 | Immunomodulatory Molecule IRAK-M Balances Macrophage Polarization and Determines Macrophage Responses during Renal Fibrosis. |
| Q36775843 | Immunoparalysis and adverse outcomes from critical illness |
| Q34279235 | Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors |
| Q47648843 | Interferon-β Improves Sepsis-related Alveolar Macrophage Dysfunction and Post-septic ARDS-related Mortality. |
| Q41843770 | Loss of the innate immunity negative regulator IRAK-M leads to enhanced host immune defense against tumor growth |
| Q45942633 | MDP-Induced selective tolerance to TLR4 ligands: impairment in NOD2 mutant Crohn's disease patients. |
| Q35039679 | Macrophage immunoregulatory pathways in tuberculosis |
| Q39686934 | Mechanical ventilation modulates TLR4 and IRAK-3 in a non-infectious, ventilator-induced lung injury model. |
| Q36745742 | MicroRNA in TLR signaling and endotoxin tolerance. |
| Q37079814 | Molecular and cellular aspects of sepsis-induced immunosuppression |
| Q40177009 | Monocyte mRNA phenotype and adverse outcomes from pediatric multiple organ dysfunction syndrome |
| Q28588300 | NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses |
| Q30392817 | Postinfluenza bacterial pneumonia: host defenses gone awry |
| Q37016121 | Pretreatment with the Gram-positive bacterial cell wall molecule peptidoglycan improves bacterial clearance and decreases inflammation and mortality in mice challenged with Pseudomonas aeruginosa |
| Q37029199 | Pretreatment with the Gram-positive bacterial cell wall molecule peptidoglycan improves bacterial clearance and decreases inflammation and mortality in mice challenged with Staphylococcus aureus |
| Q36312347 | Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages |
| Q36553864 | Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212. |
| Q36685571 | Regulations and roles of the interleukin-1 receptor associated kinases (IRAKs) in innate and adaptive immunity |
| Q34997280 | Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. |
| Q33788357 | Serum interleukin-1 receptor antagonist is an early indicator of colitis onset in Galphai2-deficient mice |
| Q41634421 | Severe Listeria monocytogenes infection induces development of monocytes with distinct phenotypic and functional features |
| Q52603956 | TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules |
| Q37374200 | The interleukin-1 receptor-associated kinase M selectively inhibits the alternative, instead of the classical NFkappaB pathway |
| Q37076790 | The involvement of the interleukin-1 receptor-associated kinases (IRAKs) in cellular signaling networks controlling inflammation |
| Q37408646 | The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis |
| Q46895698 | Toll-Like Receptor Ligand-Induced Liver Injury in D-Galactosamine-Sensitized Mice: Differences between TLR7/8 and TLR9 Ligands, Cytokine Patterns, and Cross-Tolerance Induction by TLR2 Ligand Pretreatment. |
| Q24296469 | Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4 |
| Q39286551 | Wear particles promote endotoxin tolerance in macrophages by inducing interleukin-1 receptor-associated kinase-M expression |
| Q38139929 | When host defense goes awry: Modeling sepsis-induced immunosuppression |
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