Iron-induced reactive oxygen species mediate transporter DMT1 endocytosis and iron uptake in intestinal epithelial cells.

scientific article published on 19 August 2015

Iron-induced reactive oxygen species mediate transporter DMT1 endocytosis and iron uptake in intestinal epithelial cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPCELL.00412.2014
P698PubMed publication ID26289753
P5875ResearchGate publication ID281171743

P50authorAlvaro Olivera-NappaQ59680869
Marco T. NunezQ64878456
J Cristian SalgadoQ79399968
P2093author name stringZiomara P Gerdtzen
Andrés Esparza
P2860cites workRegulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem ironQ24298922
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Dynamic Traffic through the Recycling Compartment Couples the Metal Transporter Nramp2 (DMT1) with the Transferrin ReceptorQ28504959
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Signal transduction by reactive oxygen speciesQ29615230
Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutaseQ29619948
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Dimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide-generated hydroxyl radicalQ35421426
A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption.Q35595443
Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary diseaseQ35745445
Iron and copper metabolismQ36236016
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Apical distribution of HFE-beta2-microglobulin is associated with inhibition of apical iron uptake in intestinal epithelia cells.Q38311483
Effect of DMT1 knockdown on iron, cadmium, and lead uptake in Caco-2 cellsQ38361808
Hepcidin inhibits apical iron uptake in intestinal cells.Q40061915
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Progressive iron accumulation induces a biphasic change in the glutathione content of neuroblastoma cellsQ40521283
Caco-2 cell line: a system for studying intestinal iron transport across epithelial cell monolayersQ41656548
Endocytic pathways in polarized Caco-2 cells: identification of an endosomal compartment accessible from both apical and basolateral surfacesQ41745312
Radioiron absorption in anemic dogs; fluctuations in the mucosal block and evidence for a gradient of absorption in the gastrointestinal tractQ42017478
Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1.Q42464316
The transcytosis of divalent metal transporter 1 and apo-transferrin during iron uptake in intestinal epitheliumQ42525812
Reactive oxygen species as mediators of membrane-dependent signaling induced by ultrafine particlesQ43008719
Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA damage.Q43702891
Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific speciesQ44207671
Distinct targeting and recycling properties of two isoforms of the iron transporter DMT1 (NRAMP2, Slc11A2).Q46942219
Evidence for cadmium uptake through Nramp2: metal speciation studies with Caco-2 cellsQ49202451
Fluorescence analysis of the labile iron pool of mammalian cells.Q52264375
Iron, copper, and zinc transport: inhibition of divalent metal transporter 1 (DMT1) and human copper transporter 1 (hCTR1) by shRNA.Q54340148
Quantification of Total Oxidant Scavenging Capacity of Antioxidants for Peroxynitrite, Peroxyl Radicals, and Hydroxyl RadicalsQ57272087
P433issue8
P921main subjectreactive oxygen speciesQ424361
P304page(s)C558-67
P577publication date2015-08-19
P1433published inAmerican Journal of Physiology - Cell PhysiologyQ2227080
P1476titleIron-induced reactive oxygen species mediate transporter DMT1 endocytosis and iron uptake in intestinal epithelial cells
P478volume309

Reverse relations

cites work (P2860)
Q93129521Aryl hydrocarbon receptor ligands enhance lung immunity through intestinal IKKβ pathways
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