scholarly article | Q13442814 |
P2093 | author name string | Christian Sell | |
Hong Zhang | |||
Henry Hoff | |||
P2860 | cites work | Cancer Research | Q326097 |
Journal of Biological Chemistry | Q867727 | ||
Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1 | Q24304774 | ||
Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor | Q24307508 | ||
A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family | Q24323752 | ||
Role of IRS-2 in insulin and cytokine signalling | Q24337494 | ||
Structure and physiological function of calpains | Q24530607 | ||
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Q25938984 | ||
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein | Q28116980 | ||
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307) | Q28139056 | ||
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action | Q28199220 | ||
Estradiol increases IRS-1 gene expression and insulin signaling in breast cancer cells | Q28202098 | ||
Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3'-kinase inhibition | Q33962150 | ||
Disruption of the M2 gene of murine gammaherpesvirus 68 alters splenic latency following intranasal, but not intraperitoneal, inoculation | Q34331333 | ||
Calcium-activated neutral protease (calpain) system: structure, function, and regulation | Q37767409 | ||
Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis | Q39674453 | ||
The IRS-1 signaling system | Q40682085 | ||
Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin | Q40722638 | ||
C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP. | Q40750201 | ||
Characterization of calcium release-activated apoptosis of LNCaP prostate cancer cells | Q40831672 | ||
Insulin receptor substrate-1 and phosphatidylinositol 3-kinase regulate extracellular signal-regulated kinase-dependent and -independent signaling pathways during myogenic differentiation | Q40989063 | ||
The insulin-induced down-regulation of IRS-1 in 3T3-L1 adipocytes is mediated by a calcium-dependent thiol protease | Q41173254 | ||
Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway | Q41616329 | ||
Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase | Q41848203 | ||
Insulin stimulates the degradation of IRS-1 in 3T3-L1 adipocytes | Q41938340 | ||
Insulin receptor substrate 1 is a target for the pure antiestrogen ICI 182,780 in breast cancer cells | Q42470095 | ||
The insulin receptor substrate (IRS-1) is a PEST protein that is susceptible to calpain degradation in vitro | Q42502766 | ||
IGF-I regulates IRS-1 expression in 3T3-L1 adipocytes | Q42818888 | ||
Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion | Q46980867 | ||
Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis | Q47761964 | ||
Association of insulin receptor substrate 3 with SH2 domain-containing proteins in rat adipocytes | Q47922589 | ||
A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases | Q48014886 | ||
Thapsigargin induces a calmodulin/calcineurin-dependent apoptotic cascade responsible for the death of prostatic cancer cells. | Q51080013 | ||
Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway. | Q52828725 | ||
Calpain and caspase: can you tell the difference?, by Kevin K.W. Wang | Q58115473 | ||
Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function | Q73019421 | ||
Insulin-like growth factor I-mediated degradation of insulin receptor substrate-1 is inhibited by epidermal growth factor in prostate epithelial cells | Q73794088 | ||
Mechanism and role of growth arrest in programmed (apoptotic) death of prostatic cancer cells induced by thapsigargin | Q73868526 | ||
Mitogen-independent phosphorylation of S6K1 and decreased ribosomal S6 phosphorylation in senescent human fibroblasts | Q74172357 | ||
Thapsigargin analogues for targeting programmed death of androgen-independent prostate cancer cells | Q78181254 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
P304 | page(s) | 352-358 | |
P577 | publication date | 2003-10-01 | |
P1433 | published in | Experimental Cell Research | Q1524289 |
P1476 | title | Downregulation of IRS-1 protein in thapsigargin-treated human prostate epithelial cells | |
P478 | volume | 289 |