Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway.

scientific article published on 31 May 2016

Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MBIO.01823-15
P932PMC publication ID4895119
P698PubMed publication ID27247234

P50authorVishukumar AimaniandaQ56815244
Anne AmmerdorfferQ37366518
Mark S GresnigtQ48356159
P2093author name stringX Wang
J P Latgé
K L Becker
M G Netea
L A B Joosten
F L van de Veerdonk
C W Jacobs
R P Gazendam
P2860cites workCharacterization of FIBCD1 as an acetyl group-binding receptor that binds chitinQ24310140
Polymorphisms and haplotypes of acid mammalian chitinase are associated with bronchial asthmaQ24642215
Chitin induces accumulation in tissue of innate immune cells associated with allergyQ24655812
Kindlin-3-independent adhesion of neutrophils from patients with leukocyte adhesion deficiency type III.Q52881311
Pattern recognition pathways leading to a Th2 cytokine bias in allergic bronchopulmonary aspergillosis patients.Q53146228
Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.Q54435250
Overview of the interleukin-1 family of ligands and receptors.Q54536457
Role of complement and Fc receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatusQ56942510
Purification and characterization of an endo-1,3-beta-glucanase from Aspergillus fumigatusQ61489164
Colorimetric determination of chitosanQ64360834
Effects of complement inactivation and IgG depletion on skin reactivity to autologous serum in chronic idiopathic urticariaQ74308264
Use of chitosan in compressed tablets of diclofenac sodium: inhibition of drug release in an acidic environmentQ74464573
A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonistQ28540595
Fcgamma receptors as regulators of immune responsesQ29615584
A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatusQ33398514
Spectrum and mechanisms of inflammasome activation by chitosanQ33778067
The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatusQ34334002
Innate sensing of chitin and chitosanQ34550732
A chitinase-like protein in the lung and circulation of patients with severe asthmaQ34713773
Soluble beta-glucan polysaccharide binding to the lectin site of neutrophil or natural killer cell complement receptor type 3 (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cellsQ34733788
Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.Q35145107
Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycansQ35187024
Lectin site ligation of CR3 induces conformational changes and signalingQ35728343
Dectin-1 is required for beta-glucan recognition and control of fungal infectionQ35837153
Antibodies generated against conserved antigens expressed by bacteria and allergen-bearing fungi suppress airway diseaseQ37478109
Novel structural features in Candida albicans hyphal glucan provide a basis for differential innate immune recognition of hyphae versus yeast.Q37563456
Tasting the fungal cell wallQ37756214
Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury.Q37807414
Allergic bronchopulmonary aspergillosis in asthma and cystic fibrosisQ37878272
Myeloid C-type lectin receptors in pathogen recognition and host defenseQ37880419
Kindlin-3 in the immune systemQ38198641
Functional duality of the cell wallQ38220902
The role of interleukin-1 family members in the host defence against Aspergillus fumigatusQ38232426
Antifungal innate immunity: recognition and inflammatory networksQ38295131
Impact of immune complex size and glycosylation on IgG binding to human FcγRsQ39178687
Binding of IgG-opsonized particles to Fc gamma R is an active stage of phagocytosis that involves receptor clustering and phosphorylationQ40370324
An anti-inflammatory property of Candida albicans β-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanismQ40834677
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.Q42132922
FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cellsQ42202518
Recognition and blocking of innate immunity cells by Candida albicans chitinQ42727068
Alkali- or acid-induced changes in structure, moisture absorption ability and deacetylating reaction of β-chitin extracted from jumbo squid (Dosidicus gigas) pensQ44593641
Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3.Q44947091
Mannose binding lectin enhances IL-1beta and IL-10 induction by non-lipopolysaccharide (LPS) components of Neisseria meningitidisQ45069237
LAD-1/variant syndrome is caused by mutations in FERMT3.Q46209404
NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype.Q46722645
Determination of the degree of acetylation of chitosan by UV spectrophotometry using dual standardsQ46929948
Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletionQ47631769
P433issue3
P921main subjectcell wallQ128700
chitinQ161219
P577publication date2016-05-31
P1433published inmBioQ15817061
P1476titleAspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway
P478volume7

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cites work (P2860)
Q3894983930 years of battling the cell wall
Q64056532A Soluble Immune Effector Binds Both Fungi and Bacteria via Separate Functional Domains
Q53689793Acidic mammalian chitinase negatively affects immune responses during acute and chronic Aspergillus fumigatus exposure.
Q92320533Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance
Q92568487Aspergillus fumigatus corneal infection is regulated by chitin synthases and by neutrophil-derived acidic mammalian chitinase
Q41997165Aspergillus fumigatus morphology and dynamic host interactions
Q57047431Chemical synthesis and application of biotinylated oligo-α-(1→3)-D-glucosides to study the antibody and cytokine response against the cell wall α-(1→3)-D-glucan of Aspergillus fumigatus
Q47296348Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis.
Q59353254Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells
Q50134170Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to Aspergillus fumigatus spores.
Q55480753Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.
Q48163129Immune Recognition of Fungal Polysaccharides.
Q33810700Innate Lung Defense during Invasive Aspergillosis: New Mechanisms
Q40382694M-ficolin is present in Aspergillus fumigatus infected lung and modulates epithelial cell immune responses elicited by fungal cell wall polysaccharides
Q39143535Modulation of Human Immune Response by Fungal Biocontrol Agents
Q46246454Natural Killer Cells in Antifungal Immunity
Q64119332Pro-Inflammatory Responses in Human Bronchial Epithelial Cells Induced by Spores and Hyphal Fragments of Common Damp Indoor Molds
Q64263816Reciprocal Inhibition of Adiponectin and Innate Lung Immune Responses to Chitin and
Q40351228Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation.
Q93014045The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species
Q54131701[Spleen tyrosine kinase inhibits proliferation and promotes apoptosis of colorectal cancer cells in vitro via regulating Fra-1].

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