rabies immunoglobulin

antiviral medication

DBpedia resource is: http://dbpedia.org/resource/Rabies_immunoglobulin

Abstract is: Rabies immunoglobulin (RIG) is a medication made up of antibodies against the rabies virus. It is used to prevent rabies following exposure. It is given after the wound is cleaned with soap and water or povidone-iodine and is followed by a course of rabies vaccine. It is given by injection into the site of the wound and into a muscle. It is not needed in people who have been previously vaccinated against rabies. Common side effects include pain at the site of injection, fever, and headache. Severe allergic reactions such as anaphylaxis may rarely occur. Use during pregnancy is not known to harm the baby. It works by binding to the rabies virus before it can enter nerve tissue. After the virus has entered the central nervous system, rabies immunoglobulin is no longer useful. The use of rabies immunoglobulin in the form of blood serum dates from 1891. Use became common within medicine in the 1950s. It is on the World Health Organization's List of Essential Medicines. Rabies immunoglobulin is expensive and hard to come by in the developing world. In the United States it is estimated to be more than US$1,000.00 per dose. It is made from the blood plasma of people or horses who have high levels of the antibody in their blood. The horse version is less expensive but has a higher rate of side effects.

rabies immunoglobulin is …
instance of (P31):
essential medicineQ35456
medicationQ12140

sublass of (P279):
antiserumQ420496

External links are
P267ATC codeJ06AA06
J06BB05
P9635electronic Essential Medicines List medicine ID462
P2671Google Knowledge Graph ID/g/11c2q5gh5s
P6366Microsoft Academic ID2780494762
P11143WikiProjectMed IDRabies immunoglobulin

P2175medical condition treatedrabiesQ39222
P3489pregnancy categoryUS pregnancy category CQ28123617

Reverse relations

main subject (P921)
Q96579670A Phase 3, Randomised, Open-Label, Non-inferiority Trial Evaluating Anti-Rabies Monoclonal Antibody Cocktail (TwinrabTM) Against Human Rabies Immunoglobulin (HRIG)
Q100431862A Phase 3, Randomised, Open-Label, Non-inferiority Trial Evaluating Anti-Rabies Monoclonal Antibody Cocktail (TwinrabTM) Against Human Rabies Immunoglobulin (HRIG)
Q93633766A collaborative study to establish an International Standard Rabies immunoglobulin of human origin
Q99714760Abandon of intramuscular administration of rabies immunoglobulin for post-exposure prophylaxis in the revised guidelines in the Netherlands in 2018: cost and volume savings
Q56576872Combination therapy of rabies-infected mice with inhibitors of pro-inflammatory host response, antiviral compounds and human rabies immunoglobulin
Q47616794Comparison of a Novel Human Rabies Monoclonal Antibody to Human Rabies Immunoglobulin for Postexposure Prophylaxis: A Phase 2/3, Randomized, Single-Blind, Noninferiority, Controlled Study
Q72593752Confirmation of need for rabies immunoglobulin as well as post-exposure vaccine
Q39730585Equine rabies immunoglobulin: a study on its clinical safety.
Q46778540Evaluation of a new premedication protocol for administration of equine rabies immunoglobulin in patients with hypersensitivity
Q77429475Evaluation of the safety, immunogenicity, and pharmacokinetic profile of a new, highly purified, heat-treated equine rabies immunoglobulin, administered either alone or in association with a purified, Vero-cell rabies vaccine
Q37530343Feasibility of reducing rabies immunoglobulin dosage for passive immunization against rabies: results of In vitro and In vivo studies
Q68162415Human rabies immunoglobulin assayed by the rapid fluorescent focus inhibition test suppresses active rabies immunization
Q47571006Immunogenic response in obese patients undergoing rabies post-exposure prophylaxis with combined equine rabies immunoglobulin and rabies vaccination
Q49502107Immunogenicity and safety of WHO-approved TRC-ID regimen with a chromatographically purified Vero cell rabies vaccine with or without rabies immunoglobulin in children
Q40300404Injecting rabies immunoglobulin (RIG) into wounds only: A significant saving of lives and costly RIG.
Q68515861Interaction of rabies vaccine with human rabies immunoglobulin and reliability of a 2-1-1 schedule application for postexposure treatment
Q69487588Intravenous human rabies immunoglobulin for post-exposure prophylaxis: serum rabies neutralizing antibody concentrations and side-effects
Q36560046Is injecting a finger with rabies immunoglobulin dangerous?
Q45740467Issues of human rabies immunoglobulin and vaccine: policy versus practice
Q72146050Methods for the purification of equine rabies immunoglobulin: effects on yield and biological activity
Q97561459RABIES IMMUNOGLOBULIN: BRIEF HISTORY AND RECENT EXPERIENCES IN CÔTE D'IVOIRE
Q41588040Rabies Vaccine and Rabies Immunoglobulin in Cambodia: Use and Obstacles to Use.
Q33338456Rabies post-exposure prophylaxis in the Philippines: health status of patients having received purified equine F(ab')(2) fragment rabies immunoglobulin (Favirab).
Q39374912Rabies post-exposure prophylaxis with purified equine rabies immunoglobulin: one-year follow-up of patients with laboratory-confirmed category III rabies exposure in the Philippines
Q40340145Role of systemic injection of rabies immunoglobulin in rabies vaccination
Q64233525Serum Sickness after Equine Rabies Immunoglobulin in Identical Male Twins: Two Case Reports
Q50730214Sex- and age-related differences in rabies immunoglobulin hypersensitivity.
Q64129499The comparison of the WHO standard rabies immunoglobulin and the national standard human rabies immunoglobulin used in the rapid fluorescent focus inhibition test (RFFIT)
Q86725837The importance of rabies immunoglobulin in postexposure prophylaxis
Q73240336Therapeutic failures with rabies vaccine and rabies immunoglobulin
Q84087361There is a need for regularly updated information on rabies immunoglobulin availability in rabies endemic countries
Q38997495Two decades of pharmacovigilance and clinical experience with highly purified rabies immunoglobulin F(ab')2 fragments
Q91603115Using a modified rabies immunoglobulin protocol in a crisis of unavailability: Ethical and practical challenges
Q92506596Wound-only injection of rabies immunoglobulin (RIG) saves lives and costs less than a dollar per patient by "pooling strategy"
Q74338396[10 years' of production and use of human rabies immunoglobulin in Yugoslavia]
Q90026116[Advances in Application of Rabies Immunoglobulin]

Q37155World Health Organization Model List of Essential Medicineshas part(s)P527

The articles in Wikimedia projects and languages

Arabic (ar / Q13955)غلوبيولين مناعي لداء الكلبwikipedia
      Rabies immunoglobulinwikipedia
      Inmunoglobulina contra la rabiawikipedia
      Immunoglobuline antirabiquewikipedia
      Imunoglobulin rabieswikipedia
orରାବିଜ ଇମ୍ମ୍ୟୁନୋଗ୍ଲୋବ୍ୟୁଲିନwikipedia
      Антирабический иммуноглобулинwikipedia
      Хумани антирабијски имуноглобулинwikipedia

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