Biochemical individuality and its implications for drug and carcinogen metabolism: recent insights from acetyltransferase and cytochrome P4501A2 phenotyping and genotyping in humans

scientific article published on January 1994

Biochemical individuality and its implications for drug and carcinogen metabolism: recent insights from acetyltransferase and cytochrome P4501A2 phenotyping and genotyping in humans is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3109/03602539409029783
P698PubMed publication ID8082575

P2093author name stringKadlubar FF
P2860cites workHuman cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylaminesQ24339615
Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expressionQ28116125
Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colonQ28609945
Polymorphism of theophylline metabolism in man.Q34626564
Advantages and limitations of laboratory methods for measurement of carcinogen-DNA adducts for epidemiological studiesQ35623676
Monogenic control of variations in antipyrine metabolite formation. New polymorphism of hepatic drug oxidationQ36989899
Acetylator genotype and arylamine-induced carcinogenesisQ39653636
N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cellsQ41618193
Metabolism of aromatic amines: relationships of N-acetylation, O-acetylation, N,O-acetyltransfer and deacetylation in human liver and urinary bladderQ42196896
A simple test for acetylator phenotype using caffeineQ42532035
Re: "Fried foods and the risk of colon cancer".Q44757934
Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferasesQ50336069
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectgenotypingQ912147
P304page(s)37-46
P577publication date1994-01-01
P1433published inDrug Metabolism ReviewsQ5308857
P1476titleBiochemical individuality and its implications for drug and carcinogen metabolism: recent insights from acetyltransferase and cytochrome P4501A2 phenotyping and genotyping in humans
P478volume26