Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion

scientific article published on May 2002

Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1001123027
P356DOI10.1023/A:1015930927407
P698PubMed publication ID12162436

P2093author name stringBruce R Pitt
Claudette M St Croix
Xianghong Liu
Karla J Wasserloos
Ian J Reynolds
Zi-Lue Tang
Molly S Stitt
P2860cites workZinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosisQ28244038
Apoptosis: an overviewQ28254960
Zinc protects against apoptosis of endothelial cells induced by linoleic acid and tumor necrosis factor alphaQ28378300
Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thioneinQ28509018
Nitric oxide as a bifunctional regulator of apoptosisQ33534454
Regulation of caspase activation and apoptosis by cellular zinc fluxes and zinc deprivation: A reviewQ33653462
New insights into the role of zinc in the respiratory epitheliumQ34192948
Nitric oxide as a bioregulator of apoptosisQ34219296
Zinc finger proteins as molecular targets for nitric oxide-mediated gene regulationQ34367567
Nitrosylation. the prototypic redox-based signaling mechanism.Q34381833
Induction of apoptosis in endothelial cells treated with cholesterol oxidesQ35773691
Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouseQ36509326
Analysis and sorting of living cells according to deoxyribonucleic acid contentQ36644034
The involvement of protein phosphatases in the activation of ICE/CED-3 protease, intracellular acidification, DNA digestion, and apoptosisQ36802988
Inhibition of NF-kappaB DNA binding by nitric oxideQ39716552
Nitric oxide: pathophysiological mechanismsQ40401521
The inhibitory effect of zinc on cadmium-induced cell apoptosis and reactive oxygen species (ROS) production in cell cultures.Q40885885
Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of the Bcl-2/Bax ratioQ41037855
Nitric oxide inhibits Fas-induced apoptosisQ41090104
Nitric oxide mediates intracytoplasmic and intranuclear zinc releaseQ41120612
Antiatherogenic properties of zinc: implications in endothelial cell metabolismQ41233961
Video image analysis of labile zinc in viable pancreatic islet cells using a specific fluorescent probe for zincQ41457439
Zinc and brain injuryQ41733300
Measurement of zinc in hepatocytes by using a fluorescent probe, zinquin: relationship to metallothionein and intracellular zincQ41885735
Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cellsQ42539353
Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosisQ42547800
Role of zinc in pulmonary endothelial cell response to oxidative stressQ43638728
Nitric oxide acutely inhibits neuronal energy production. The Committees on Neurobiology and Cell Physiology.Q48319224
Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikaryaQ48430368
Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury.Q50526527
Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors.Q52394794
Metallothionein, nitric oxide and zinc homeostasis in vascular endothelial cells.Q54052404
Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell deathQ54485016
Nitric oxide-dependent induction of glutathione synthesis through increased expression of gamma-glutamylcysteine synthetaseQ58748258
Translocation of zinc may contribute to seizure-induced death of neuronsQ69597365
Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expressionQ71973760
Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cellsQ72005909
Nitric oxide destroys zinc-sulfur clusters inducing zinc release from metallothionein and inhibition of the zinc finger-type yeast transcription activator LAC9Q72412254
Cellular non-heme iron content is a determinant of nitric oxide-mediated apoptosis, necrosis, and caspase inhibitionQ73643152
The influence of cadmium and zinc ions on the interferon and tumor necrosis factor production in bovine aorta endothelial cellsQ73689379
A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implantsQ73707747
Antioxidant-like properties of zinc in activated endothelial cellsQ77329736
Bcl-2 prevents caspase-independent cell deathQ77677956
Measurement of nitric oxide-mediated effects on zinc homeostasis and zinc finger transcription factorsQ77907997
Mass spectrometric analysis of nitric oxide-modified caspase-3Q78010420
P433issue1-2
P921main subjectendotheliumQ111140
P304page(s)211-217
P577publication date2002-05-01
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleNitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion
P478volume234-235

Reverse relations

cites work (P2860)
Q36045584A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis
Q28393741A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death
Q27691441Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors
Q35060790Caveolae-dependent and -independent uptake of albumin in cultured rodent pulmonary endothelial cells
Q28304250Characterization of potential S-nitrosylation sites in the myocardium
Q35123040Chronic exposure to nitric oxide alters the free iron pool in endothelial cells: role of mitochondrial respiratory complexes and heat shock proteins
Q47306535Copper and clioquinol treatment in young APP transgenic and wild-type mice: effects on life expectancy, body weight, and metal-ion levels
Q38340947CpG DNA-mediated immune response in pulmonary endothelial cells
Q36563566Functional role of intracellular labile zinc in pulmonary endothelium
Q42100473LPS-induced decrease in intracellular labile zinc, [Zn]i, contributes to apoptosis in cultured sheep pulmonary artery endothelial cells
Q41917160Manganese superoxide dismutase is not protective in bovine pulmonary artery endothelial cells at systemic oxygen levels
Q35123490Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis
Q49280996MicroRNA-17-5p aggravates lipopolysaccharide-induced injury in nasal epithelial cells by targeting Smad7.
Q93181884Modulators of inflammation in Bronchopulmonary Dysplasia
Q36003348NO mobilizes intracellular Zn2+ via cGMP/PKG signaling pathway and prevents mitochondrial oxidant damage in cardiomyocytes
Q36284883Nitric oxide and zinc homeostasis in acute lung injury
Q46901690Nitric oxide-induced nuclear translocation of the metal responsive transcription factor, MTF-1 is mediated by zinc release from metallothionein
Q33405708Nitric oxide-mediated protection of endothelial cells from hydrogen peroxide is mediated by intracellular zinc and glutathione
Q42540322Nitric-oxide-mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone
Q28397052Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation
Q37126480Postnatal estradiol up-regulates lung nitric oxide synthases and improves lung function in bronchopulmonary dysplasia
Q39147108Providencia alcalifaciens causes barrier dysfunction and apoptosis in tissue cell culture: potent role of lipopolysaccharides on diarrheagenicity
Q39387568Reaction of metal-binding ligands with the zinc proteome: zinc sensors and N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine
Q33714016Regulation of zinc homeostasis by inducible NO synthase-derived NO: nuclear metallothionein translocation and intranuclear Zn2+ release
Q81845072Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo
Q35694364The Effects of Leucine, Zinc, and Chromium Supplements on Inflammatory Events of the Respiratory System in Type 2 Diabetic Rats
Q36571426Zinc binding ligands and cellular zinc trafficking: apo-metallothionein, glutathione, TPEN, proteomic zinc, and Zn-Sp1.
Q33893336Zn2+ efflux through lysosomal exocytosis prevents Zn2+-induced toxicity
Q44527143iNOS activity is essential for endothelial stress gene expression protecting against oxidative damage

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