Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance

scientific article published on June 2002

Rat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/IJC.10410
P698PubMed publication ID12115478
P5875ResearchGate publication ID11264171

P2093author name stringLisa Yee
Peter Li
Kermit L Carraway
Philip S Rudland
Shari A Price-Schiavi
Scott Jepson
Maria Arango
P2860cites workComplete sequence of the human mucin MUC4: a putative cell membrane-associated mucinQ22008776
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogeneQ27860693
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogeneQ28286890
Post-transcriptional regulation of a milk membrane protein, the sialomucin complex (Ascites sialoglycoprotein (ASGP)-1/ASGP-2, rat muc4), by transforming growth factor betaQ28575829
An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signalingQ28582768
Reversible disruption of cell-matrix and cell-cell interactions by overexpression of sialomucin complexQ28583170
Heregulin induces tyrosine phosphorylation of HER4/p180erbB4Q28589513
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancerQ29547699
Prognostic and predictive significance of ErbB-2 breast tumor levels measured by enzyme immunoassayQ31826526
Topology of cell adhesion moleculesQ33836280
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signalingQ33886341
ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependencyQ33963261
Mucin gene expression in the human endocervixQ34310299
A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cellsQ36678230
p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factorQ36767887
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activityQ36914246
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridizationQ37054834
Expression of MUC2 epithelial mucin in breast carcinomaQ37242467
Why are proteins O-glycosylated?Q37951273
Isolation and partial characterization of ascites sialoglycoprotein-2 of the cell surface sialomucin complex of 13762 rat mammary adenocarcinoma cellsQ38342416
Structural and functional aspects of tumor cell sialomucinsQ38350269
Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): a study of incidence and correlation with outcome in breast cancerQ38463900
A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.Q40242537
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic diseaseQ40630247
A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signalingQ40673334
The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylationQ41080406
Bindings of the lectins Griffonia simplicifolia-1 and pokeweed mitogen mark discrete stages of myoepithelial-like differentiation of cell lines from the rat mammary glandQ41697369
Differential localization of ErbB2 in different tissues of the rat female reproductive tract: implications for the use of specific antibodies for ErbB2 analysisQ42511390
The neu oncogene encodes an epidermal growth factor receptor-related proteinQ42812960
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatmentQ46641346
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptorQ48369441
Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridizationQ48801012
Identification of cell types in the developing goat mammary gland.Q52174877
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)783-791
P577publication date2002-06-01
P1433published inInternational Journal of CancerQ332492
P1476titleRat Muc4 (sialomucin complex) reduces binding of anti-ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance
P478volume99