A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation

scientific article published on May 2014

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.1703
P932PMC publication ID4058022
P698PubMed publication ID24811707
P5875ResearchGate publication ID262192490

P50authorXiao-Jie YuQ82377126
Liqin DuQ89842627
P2093author name stringGail E Tomlinson
Alexander Pertsemlidis
Yidong Chen
Tzu-Hung Hsiao
Zhenze Zhao
Xiuye Ma
Adam Kosti
Uthra Suresh
Gregory Lin
P2860cites workmiR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1.Q37340463
The proto-oncogene KRAS is targeted by miR-200cQ37649657
MicroRNA function in cancer: oncogene or a tumor suppressor?Q37655612
Neuroblastoma: biology, prognosis, and treatmentQ37683919
Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinomaQ39243346
HOXC9 links cell-cycle exit and neuronal differentiation and is a prognostic marker in neuroblastomaQ39555632
MicroRNA-125b promotes neuronal differentiation in human cells by repressing multiple targetsQ39820130
High-content screening as a universal tool for fingerprinting of cytotoxicity of nanoparticlesQ39885387
Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity researchQ39908892
Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequenceQ39993069
A simple, flexible, nonfluorescent system for the automated screening of neurite outgrowthQ40338925
Role of cyclic amp in differentiation of human neuroblastoma cells in cultureQ40341427
MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1Q42123071
Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screeningQ42809108
Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma.Q44328896
NeuroblastomaQ54265665
Induction of neurite outgrowth in the IMR-32 human neuroblastoma cell line by nerve growth factor.Q55490611
Phenotypic changes of human neuroblastoma cells in culture induced by 12‐O‐tetradecanoyl‐phorbol‐13‐acetateQ71005261
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cellsQ21245271
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicingQ24631683
Widespread microRNA repression by Myc contributes to tumorigenesisQ24647067
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer modelQ24655262
Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a children's oncology group studyQ24658339
Combinatorial microRNA target predictionsQ27860510
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
Silencing of microRNAs in vivo with 'antagomirs'Q27860891
Characterization of microRNA expression profiles in normal human tissuesQ29615492
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolutionQ29616370
A quantitative method for analysis of in vitro neurite outgrowthQ33287785
Differentiation therapy of leukemia: 3 decades of developmentQ33409795
Automated microscopy for high-content RNAi screeningQ33533546
Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopmentQ33608739
MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastomaQ33803485
A rapid, inexpensive high throughput screen method for neurite outgrowthQ33828248
Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer GroupQ33876841
microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastomaQ33893064
microRNA and cancerQ33954625
Differentiating agents in pediatric malignancies: retinoids in neuroblastoma.Q34108090
Neuroblastoma: biological insights into a clinical enigmaQ34180699
A new module in neural differentiation control: two microRNAs upregulated by retinoic acid, miR-9 and -103, target the differentiation inhibitor ID2Q34357876
miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma.Q34482630
MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2Q35042737
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in miceQ35086711
Solid Tumor Differentiation Therapy - Is It Possible?Q36071880
The MYCN oncogene is a direct target of miR-34aQ36926506
MicroRNA reexpression as differentiation therapy in cancerQ37286627
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
microRNAQ310899
neuroblastomaQ938205
P304page(s)2499-2512
P577publication date2014-05-01
P1433published inOncotargetQ1573155
P1476titleA high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation
P478volume5

Reverse relations

cites work (P2860)
Q40528981A combined gene expression and functional study reveals the crosstalk between N-Myc and differentiation-inducing microRNAs in neuroblastoma cells
Q38747810Action of HMGB1 on miR-221/222 cluster in neuroblastoma cell lines
Q36307073Association between single nucleotide polymorphisms in MiR219-1 and MiR137 and susceptibility to schizophrenia in a Chinese population
Q91707651Cancer Stem Cells and Neuroblastoma: Characteristics and Therapeutic Targeting Options
Q50003166Differential expression of microRNAs in the normal skin of the Han and Uyghur populations in Xinjiang Province
Q35096787Genetic mutation of p53 and suppression of the miR-17∼92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D Signaling
Q89899063High-throughput fluorescence-based screen identifies the neuronal microRNA miR-124 as a positive regulator of alphavirus infection
Q38690311Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
Q47304723Induction of morphological and functional differentiation of human neuroblastoma cells by miR-124.
Q28082679Key nodes of a microRNA network associated with the integrated mesenchymal subtype of high-grade serous ovarian cancer
Q38531097Long noncoding RNAs and neuroblastoma
Q34718013MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer
Q35814865MicroRNA library screening identifies growth-suppressive microRNAs that regulate genes involved in cell cycle progression and apoptosis.
Q52640461MicroRNA-194 Regulates the Development and Differentiation of Sensory Patches and Statoacoustic Ganglion of Inner Ear by Fgf4.
Q92193233MicroRNAs in neuroblastoma tumorigenesis, therapy resistance, and disease evolution
Q92015499Opportunities and challenges of circulating biomarkers in neuroblastoma
Q58766575Phenotypic miRNA Screen Identifies miR-26b to Promote the Growth and Survival of Endothelial Cells
Q89842629The PLAGL2/MYCN/miR-506-3p interplay regulates neuroblastoma cell fate and associates with neuroblastoma progression
Q26740283The emerging role of miR-506 in cancer
Q90054054The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5
Q31095310Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data
Q47121878Unveiling massive numbers of cancer-related urinary-microRNA candidates via nanowires
Q53695419miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer.
Q42329734miR-506 suppresses neuroblastoma metastasis by targeting ROCK1
Q60302214microRNA-2110 functions as an onco-suppressor in neuroblastoma by directly targeting Tsukushi
Q38300511microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest.

Search more.