Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells

scientific article published in June 2002

Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2337/DIABETES.51.6.1815
P698PubMed publication ID12031969
P5875ResearchGate publication ID11340486

P2093author name stringAdama Kamagate
Oscar Diaz-Horta
André Herchuelz
Françoise Van Eylen
P2860cites workCaspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-betaQ22011091
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
apoptotic processQ14599311
overexpressionQ61643320
P304page(s)1815-1824
P577publication date2002-06-01
P1433published inDiabetesQ895262
P1476titleNa/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells
P478volume51

Reverse relations

cites work (P2860)
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Q37066756Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta
Q28582648Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis
Q34649447Caspase-12 and ER-stress-mediated apoptosis: the story so far.
Q78419821Current literature in diabetes
Q39665083ER-targeted Bcl-2 and inhibition of ER-associated caspase-12 rescue cultured immortalized cells from ethanol toxicity
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Q40547097Heterozygous inactivation of plasma membrane Ca(2+)-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability
Q35123543Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass
Q46182848IL-1beta caused pancreatic beta-cells apoptosis is mediated in part by endoplasmic reticulum stress via the induction of endoplasmic reticulum Ca2+ release through the c-Jun N-terminal kinase pathway
Q36910693Initiation and execution of lipotoxic ER stress in pancreatic beta-cells
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Q39675611Plasma membrane Ca2+-ATPase overexpression depletes both mitochondrial and endoplasmic reticulum Ca2+ stores and triggers apoptosis in insulin-secreting BRIN-BD11 cells.
Q50927758Pretreatment of donor islets with the Na(+) /Ca(2+) exchanger inhibitor improves the efficiency of islet transplantation.
Q36323025Regulation of the expression and processing of caspase-12
Q86505112Sodium/calcium exchanger is upregulated by sulfide signaling, forms complex with the β1 and β3 but not β2 adrenergic receptors, and induces apoptosis
Q33673823Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1
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Q38038659β-Cell preservation and regeneration in diabetes by modulation of β-cell Ca²⁺ homeostasis

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