Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine

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Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine is …
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scholarly articleQ13442814

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P356DOI10.1016/S0360-3016(01)02820-6
P8608Fatcat IDrelease_uvtsdkq5mvdjro2tk4yl5pmewu
P698PubMed publication ID12007958

P50authorDavid J GrdinaQ120671767
Ralph WeichselbaumQ19668192
P2093author name stringNikolai N Khodarev
Yasushi Kataoka
Jeffrey S Murley
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Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of actionQ72187689
WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cellsQ74125114
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Activation of nuclear factor kappaB by polyamines in breast cancer cellsQ38318688
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The human interleukin-2 receptor: normal and abnormal expression in T cells and in leukemias induced by the human T-lymphotropic retrovirusesQ39504656
Activation of NFkappaB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cellsQ40801438
Protection of human tumor cells of differing radiosensitivity by WR-1065.Q40863524
Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell linesQ40871836
Antioxidant and redox regulation of gene transcriptionQ40989720
Overexpression of manganese superoxide dismutase in DU145 human prostate carcinoma cells has multiple effects on cell phenotypeQ42454974
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)180-189
P577publication date2002-05-01
P1433published inInternational Journal of Radiation Oncology Biology PhysicsQ2296252
P1476titleActivation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine
P478volume53