The toxicity of chemically deglycosylated ricin A-chain in mice

scientific article published on February 1, 1992

The toxicity of chemically deglycosylated ricin A-chain in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0192-0561(92)90041-I
P953full work available at URLhttps://api.elsevier.com/content/article/PII:019205619290041I?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:019205619290041I?httpAccept=text/xml
P698PubMed publication ID1624227

P50authorEllen VitettaQ4795310
Jonathan W UhrQ106192665
P2093author name stringJ. Richardson
A. M. Soler-Rodriguez
P2860cites workA severe combined immunodeficiency mutation in the mouseQ28274531
Toxicity of abrin and ricin in mice and dogsQ34661780
THE HISTOLOGICAL CHANGES PRODUCED BY RICIN AND ABRIN INTOXICATIONS.Q36227654
Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteinsQ36356510
The biology of cachectin/TNF--a primary mediator of the host responseQ38269386
Modification of the carbohydrate in ricin with metaperiodate and cyanoborohydride mixtures: effect on binding, uptake and toxicity to parenchymal and non-parenchymal cells of rat liverQ38352020
Assays for tumour necrosis factor and related cytokinesQ38601014
Redesigning nature's poisons to create anti-tumor reagentsQ39682102
Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor).Q39839327
The preparation and cytotoxic properties of antibody-toxin conjugatesQ40330042
Ricin: The toxic protein of castor oil seedsQ40905808
Renal lesion in nude miceQ40978070
Comparison of in vitro cell cytotoxic assays for tumor necrosis factorQ44180676
A vascular permeability factor elaborated from lymphocytes. I. Demonstration in patients with nephrotic syndromeQ45919524
Statistics for Business and EconomicsQ58272591
Effect of mild charge modification of albumin on renal excretion in the ratQ68046328
Effect of chemical deglycosylation on the in vivo fate of ricin A-chainQ68808837
Vascular permeability factor, an endothelial cell mitogen related to PDGFQ69116052
Modification of the carbohydrate in ricin with metaperiodate-cyanoborohydride mixtures. Effects on toxicity and in vivo distributionQ70078986
The preparation of deglycosylated ricin by recombination of glycosidase-treated A- and B-chains: effects of deglycosylation on toxicity and in vivo distributionQ70319714
Studies on the Toxic Action of RicinQ72843597
THE ROLE OF ENDOTOXIN IN THE EXTRACELLULAR COAGULATION OF LIMULUS BLOODQ76956779
Biochemical mechanisms and morphological selectivity in hepatotoxicity: studies in cultures of hepatic-parenchymal and non-parenchymal cellsQ93654492
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
immunologyQ101929
P304page(s)281-291
P577publication date1992-02-01
P1433published inInternational Journal of ImmunopharmacologyQ24031590
P1476titleThe toxicity of chemically deglycosylated ricin A-chain in mice
P478volume14

Reverse relations

cites work (P2860)
Q36829224Anthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions
Q35878388Characterization of Ricin and R. communis Agglutinin Reference Materials
Q36455711Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome
Q73102077Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice
Q37029370Linked-in: design and efficacy of antibody drug conjugates in oncology
Q36301063N-glycosylation does not affect the catalytic activity of ricin a chain but stimulates cytotoxicity by promoting its transport out of the endoplasmic reticulum
Q41540554Preclinical investigation of the antitumour effects of anti-CD19-idarubicin immunoconjugates
Q51496298Progress in biological threat agent vaccine development: a repeat-dose toxicity study of a recombinant ricin toxin A-chain (rRTA) 1-33/44-198 vaccine (RVEc) in male and female New Zealand white rabbits.
Q41959941Ricin induces the production of tumour necrosis factor-alpha and interleukin-1 beta by human peripheral-blood mononuclear cells
Q52553231Ricin toxin contains three lectin sites which contribute to its in vivo toxicity.
Q35866996The need for continued development of ricin countermeasures
Q41664945Vascular leak syndrome: a side effect of immunotherapy

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