Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic

scientific article published on April 2002

Delineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/DMD.30.4.457
P698PubMed publication ID11901101

P50authorPatrick J SinkoQ57069206
P2093author name stringAilan Guo
Peidi Hu
William Marinaro
P433issue4
P921main subjectoverexpressionQ61643320
etoposideQ418817
multiple drug resistanceQ643839
P304page(s)457-463
P577publication date2002-04-01
P1433published inDrug Metabolism and DispositionQ1261140
P1476titleDelineating the contribution of secretory transporters in the efflux of etoposide using Madin-Darby canine kidney (MDCK) cells overexpressing P-glycoprotein (Pgp), multidrug resistance-associated protein (MRP1), and canalicular multispecific organic anion transporter (cMOAT)
P478volume30

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cites work (P2860)
Q45153266A "drug cocktail" delivered by microspheres for the local treatment of rat glioblastoma
Q42846693An electrically tight in vitro blood-brain barrier model displays net brain-to-blood efflux of substrates for the ABC transporters, P-gp, Bcrp and Mrp-1.
Q39527868Calcein assay: a high-throughput method to assess P-gp inhibition.
Q30234940Clinical Implications of P-Glycoprotein Modulation in Drug-Drug Interactions.
Q36553783Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP.
Q39657896Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).
Q33995372Drug delivery across the blood-brain barrier: why is it difficult? how to measure and improve it?
Q36543091Drug-drug interactions involving membrane transporters in the human kidney
Q42429561Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir
Q36004628Functional characterization of peptide transporters in MDCKII-MDR1 cell line as a model for oral absorption studies
Q39665168Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen
Q39472771Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells
Q33614494Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance
Q38051447Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions
Q46897790Kinetic modelling of passive transport and active efflux of a fluoroquinolone across Caco-2 cells using a compartmental approach in NONMEM.
Q36271954Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application
Q34459467NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells
Q36613874Oral treatment with etoposide in small cell lung cancer - dilemmas and solutions
Q35771512Pharmacokinetic optimisation of treatment with oral etoposide.
Q44797030Physiologically based pharmacokinetic modelling of high- and low-dose etoposide: from adults to children.
Q45792529Riccardin D, a novel macrocyclic bisbibenzyl, induces apoptosis of human leukemia cells by targeting DNA topoisomerase II.
Q34983639Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition
Q46484127Species difference in intestinal absorption mechanism of etoposide and digoxin between cynomolgus monkey and rat.
Q45220374Spontaneous mitochondrial membrane potential change during apoptotic induction by quercetin in K562 and K562/adr cells.
Q36609743Strategies to assess the drug interaction potential in translational medicine
Q38853359The putative P-gp inhibitor telmisartan does not affect the transcellular permeability and cellular uptake of the calcium channel antagonist verapamil in the P-glycoprotein expressing cell line MDCK II MDR1.
Q34227679The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells.
Q38478413Transporter-Mediated Disposition of Opioids: Implications for Clinical Drug Interactions
Q35868689Tuftsin augments antitumor efficacy of liposomized etoposide against fibrosarcoma in Swiss albino mice
Q28473683Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II
Q39416207Vosaroxin: a new valuable tool with the potential to replace anthracyclines in the treatment of AML?

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