Systematic mutational analysis of the amino-terminal domain of the Listeria monocytogenes ActA protein reveals novel functions in actin-based motility.

scientific article published on December 2001

Systematic mutational analysis of the amino-terminal domain of the Listeria monocytogenes ActA protein reveals novel functions in actin-based motility. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1046/J.1365-2958.2001.02677.X
P8608Fatcat IDrelease_m7cyskps7bfuva7inu3g7pznyq
P698PubMed publication ID11886549
P5875ResearchGate publication ID227610066

P50authorJulie TheriotQ6308556
P2093author name stringD A Portnoy
M D Welch
P Lauer
J Skoble
P2860cites workStability of the Listeria monocytogenes ActA protein in mammalian cells is regulated by the N-end rule pathwayQ40826546
The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerizationQ41623792
The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complexQ41667056
Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motilityQ41753152
Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: bacterial factors, cellular ligands and signalingQ42124459
Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts.Q46134206
Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleationQ46673303
Purification and assay of the platelet Arp2/3 complexQ46913429
Use of a new integrational vector to investigate compartment-specific expression of the Bacillus subtilis spoIIM geneQ52477924
The amino-terminal part of ActA is critical for the actin-based motility of Listeria monocytogenes; the central proline-rich region acts as a stimulatorQ57857262
Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenesQ24679402
Listeria monocytogenes exploits normal host cell processes to spread from cell to cellQ24680571
Rapid and efficient site-specific mutagenesis without phenotypic selectionQ27860628
LaXp180, a mammalian ActA-binding protein, identified with the yeast two-hybrid system, co-localizes with intracellular Listeria monocytogenesQ28591200
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assemblyQ28609843
Reconstitution of actin-based motility of Listeria and Shigella using pure proteinsQ29617447
The Arp2/3 complex: a multifunctional actin organizerQ33536484
Listeria monocytogenes moves rapidly through the host-cell cytoplasm by inducing directional actin assemblyQ33735631
Control of actin assembly and disassembly at filament endsQ33840299
The Arp2/3 complex is essential for the actin-based motility of Listeria monocytogenes.Q33869141
Identification of two regions in the N-terminal domain of ActA involved in the actin comet tail formation by Listeria monocytogenes.Q33886312
Activation of the Arp2/3 complex by the Listeria acta protein. Acta binds two actin monomers and three subunits of the Arp2/3 complex.Q33921214
L. monocytogenes-induced actin assembly requires the actA gene product, a surface proteinQ34614282
The tandem repeat domain in the Listeria monocytogenes ActA protein controls the rate of actin-based motility, the percentage of moving bacteria, and the localization of vasodilator-stimulated phosphoprotein and profilinQ36237677
Motility of ActA protein-coated microspheres driven by actin polymerizationQ36333047
Actin-based movement of Listeria monocytogenes: actin assembly results from the local maintenance of uncapped filament barbed ends at the bacterium surfaceQ36382607
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complexQ36450248
ActA is a dimerQ36579143
Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cellsQ36732583
Dual roles of plcA in Listeria monocytogenes pathogenesisQ36813441
A systematic mutational analysis of hormone-binding determinants in the human growth hormone receptorQ37517460
Asymmetric distribution of the Listeria monocytogenes ActA protein is required and sufficient to direct actin-based motility.Q38291809
Actin and phosphoinositide binding by the ActA protein of the bacterial pathogen Listeria monocytogenesQ38318496
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectListeria monocytogenesQ292015
mutational analysisQ1955810
P304page(s)1163-1177
P577publication date2001-12-01
P1433published inMolecular MicrobiologyQ6895967
P1476titleSystematic mutational analysis of the amino-terminal domain of the Listeria monocytogenes ActA protein reveals novel functions in actin-based motility
P478volume42

Reverse relations

cites work (P2860)
Q88565723Actin-based motility allows Listeria monocytogenes to avoid autophagy in the macrophage cytosol
Q24548463Actin-based motility of intracellular microbial pathogens
Q30476772Bacterial shape and ActA distribution affect initiation of Listeria monocytogenes actin-based motility.
Q35756695Choosing orientation: influence of cargo geometry and ActA polarization on actin comet tails.
Q34788803Close packing of Listeria monocytogenes ActA, a natively unfolded protein, enhances F-actin assembly without dimerization
Q34315765Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors
Q24650795Evidence for the involvement of ActA in maturation of the Listeria monocytogenes phagosome
Q36613741Genome analysis of Listeria ivanovii strain G770 that caused a deadly aortic prosthesis infection
Q38884828Host actin polymerization tunes the cell division cycle of an intracellular pathogen.
Q36324377How VASP enhances actin-based motility
Q37651218Human and Helicobacter pylori Interactions Determine the Outcome of Gastric Diseases
Q30476740Large-scale quantitative analysis of sources of variation in the actin polymerization-based movement of Listeria monocytogenes
Q30579395Listeria monocytogenes actin-based motility varies depending on subcellular location: a kinematic probe for cytoarchitecture.
Q24541433Mechanism of polarization of Listeria monocytogenes surface protein ActA
Q37137631Miniature protein ligands for EVH1 domains: interplay between affinity, specificity, and cell motility
Q37058655Molecular mechanisms of cell-cell spread of intracellular bacterial pathogens
Q33769189Pleiotropic enhancement of bacterial pathogenesis resulting from the constitutive activation of the Listeria monocytogenes regulatory factor PrfA.
Q37364770Regulatory mimicry in Listeria monocytogenes actin-based motility.
Q47269520The VirAB ABC transporter is required for VirR regulation of Listeria monocytogenes virulence and resistance to nisin
Q34774585The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity
Q36739620The role of the cytoskeleton in the life cycle of viruses and intracellular bacteria: tracks, motors, and polymerization machines
Q34213677Yogi Berra, Forrest Gump, and the discovery of Listeria actin comet tails

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