Efficacy and safety of cyclosporin A ophthalmic emulsion in the treatment of moderate-to-severe dry eye disease: a dose-ranging, randomized trial. The Cyclosporin A Phase 2 Study Group

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Efficacy and safety of cyclosporin A ophthalmic emulsion in the treatment of moderate-to-severe dry eye disease: a dose-ranging, randomized trial. The Cyclosporin A Phase 2 Study Group is …
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scholarly articleQ13442814

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P356DOI10.1016/S0161-6420(00)00035-X
P698PubMed publication ID10811092

P2093author name stringD Stevenson
J Tauber
B L Reis
P2860cites workSenile atrophy of the human lacrimal gland: the contribution of chronic inflammatory diseaseQ33643546
Histology of the lacrimal gland in keratoconjunctivitis siccaQ33997341
Prevalence of dry eye in Japanese eye centersQ34369619
A patient questionnaire approach to estimating the prevalence of dry eye symptoms in patients presenting to optometric practices across CanadaQ34441489
Cytokines and autoimmune diseaseQ37433285
Prevalence of dry eye among the elderlyQ39457390
Diagnostic implications of tear protein profilesQ41858527
Mononuclear cell phenotypes and immunoglobulin gene rearrangements in lacrimal gland biopsies from patients with Sjögren's syndromeQ43585293
Keratoconjunctivitis sicca and primary Sjögren's syndrome in a Danish population aged 30-60 yearsQ44997732
Spontaneous canine keratoconjunctivitis sicca. A useful model for human keratoconjunctivitis sicca: treatment with cyclosporine eye dropsQ69674155
The autoimmune nature of aqueous tear deficiencyQ69734017
An immunohistochemical study of topical cyclosporine in vernal keratoconjunctivitisQ71064375
Endophthalmitis associated with microbial keratitisQ71833017
Topical cyclosporin treatment of keratoconjunctivitis sicca in secondary Sjögren's syndromeQ72418731
Effect of topical cyclosporin A on conjunctival T cells in patients with secondary Sjögren's syndromeQ72658445
P433issue5
P921main subjectcyclosporineQ367700
eye diseaseQ3041498
phase II clinical trialQ42824440
P304page(s)967-974
P577publication date2000-05-01
P1433published inOphthalmologyQ7098109
P1476titleEfficacy and safety of cyclosporin A ophthalmic emulsion in the treatment of moderate-to-severe dry eye disease: a dose-ranging, randomized trial. The Cyclosporin A Phase 2 Study Group
P478volume107

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cites work (P2860)
Q47121635A Prospective, Randomized Trial of Two Mucin Secretogogues for the Treatment of Dry Eye Syndrome in Office Workers
Q90615647A Review of Management Strategies for Nociceptive and Neuropathic Ocular Surface Pain
Q36296284A randomised, double-masked comparison study of diquafosol versus sodium hyaluronate ophthalmic solutions in dry eye patients
Q36908429A randomized, double-blind, placebo-controlled study of oral antioxidant supplement therapy in patients with dry eye syndrome.
Q92236581A study of refractory cases of persistent epithelial defects associated with dry eye syndrome and recurrent corneal erosions successfully treated with cyclosporine A 0.05% eye drops
Q92442286Advances in dry eye disease treatment
Q38904119Advances in the use of prodrugs for drug delivery to the eye.
Q52820593Adverse Effect Profile of Topical Ocular Administration of Fingolimod for Treatment of Dry Eye Disease.
Q79317939Anti-inflammatory therapy of dry eye
Q48126820Assessment of the effectiveness of cyclosporine nasal spray in an animal model of allergic rhinitis.
Q37071969Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression
Q24200233Autologous serum eye drops for dry eye
Q24234791Autologous serum eye drops for dry eye syndrome
Q30235522Autologous serum eye drops for dry eye.
Q36639883Challenges and pitfalls in clinical trials of treatments for dry eye.
Q38148616Changing trends in the treatment of dry-eye disease
Q34600435Character of ocular surface mucins and their alteration in dry eye disease
Q46437932Characterization of the novel ophthalmic drug carrier Sophisen in two of its derivatives: 3A Ofteno and Modusik-A Ofteno
Q56864480Ciclosporin use in dry eye disease patients
Q37782084Clinical Review: Topical Ophthalmic Use of Cyclosporin A
Q46939840Clinical evaluation of pimecrolimus eye drops for treatment of canine keratoconjunctivitis sicca: a comparison with cyclosporine A.
Q39151688Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
Q89906657Comparison of the iLUX and the LipiFlow for the Treatment of Meibomian Gland Dysfunction and Symptoms: A Randomized Clinical Trial
Q90403137Comparison of topical cyclosporine alone and topical loteprednol with cyclosporine in moderate dry eye in Indian population: A prospective study
Q37905546Cornea: Window to Ocular Immunology
Q36269034Corneal confocal scanning laser microscopy in patients with dry eye disease treated with topical cyclosporine
Q57378488Current and emerging therapy of dry eye disease. Part A: pharmacological modalities
Q37781669Current insights into ocular graft-versus-host disease
Q46857139Current treatment for dry eye syndrome
Q35572113Cyclosporine 0.05% ophthalmic emulsion for dry eye in Korea: a prospective, multicenter, open-label, surveillance study
Q45012706Cyclosporine 0.05% ophthalmic emulsion for the treatment of radiation-associated dry eye in children
Q45041371Cyclosporine 2% eye drops preparation
Q35577456Cyclosporine A delivery to the eye: A pharmaceutical challenge
Q28828737Cyclosporine Amicellar delivery system for dry eyes
Q35570541Cyclosporine ophthalmic emulsions for the treatment of dry eye: a review of the clinical evidence
Q33526896Data Monitoring Committees.
Q80347916Design and conduct of clinical trials: report of the Clinical Trials Subcommittee of the International Dry Eye WorkShop (2007)
Q33274135Differential diagnoses of conjunctivitis for clinical allergist-immunologists
Q57171838Dry Eye Assessment and Management (DREAM©) Study: Study design and baseline characteristics
Q35344219Dry eye after laser in-situ keratomileusis
Q34123349Dry eye disease
Q36799601Dry eye disease and microbial keratitis: is there a connection?
Q36916372Dry eye disease: an immune-mediated ocular surface disorder
Q34247350Dry eye in the elderly
Q42578739Dry eye syndrome
Q47639135Dry eye syndrome: developments and lifitegrast in perspective
Q39384374Dry eye. An update on epidemiology, diagnosis, therapy and new concepts
Q26852044Dry eye: an inflammatory ocular disease
Q35790953Dry eye: diagnosis and current treatment strategies
Q34338027Effect of inflammation on lacrimal gland function.
Q51836466Effects of Aging in Dry Eye.
Q46025632Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model.
Q35581180Emerging drugs for ophthalmic diseases.
Q34371781Emerging treatment options for meibomian gland dysfunction
Q35805082Expert opinion in the management of aqueous Deficient Dry Eye Disease (DED).
Q36929473Graft failure: II. Ocular surface complications
Q38090503Graft versus host disease: clinical evaluation, diagnosis and management
Q33861286HLA-DR expression as a biomarker of inflammation for multicenter clinical trials of ocular surface disease
Q34076208High-frequency topical cyclosporine 0.05% in the treatment of severe dry eye refractory to twice-daily regimen
Q58598414Impact of Vehicle Physicochemical Properties on Modeling-Based Predictions of Cyclosporine Ophthalmic Emulsion Bioavailability and Tear Film Breakup Time
Q36393194Improvement in the signs and symptoms of dry eye disease with dobesilate eye drops
Q39878699In vivo tissue distribution and efficacy studies for cyclosporin A loaded nano-decorated subconjunctival implants.
Q60047806Is Sjögren's syndrome dry eye similar to dry eye caused by other etiologies? Discriminating different diseases by dry eye tests
Q53534950Keratitis in Dry Eye Disease and Topical Ciclosporin A.
Q38608475Lifitegrast for the treatment of dry eye disease in adults
Q33727906Long-term topical cyclosporine treatment improves tear production and reduces keratoconjunctivitis in rabbits with induced autoimmune dacryoadenitis.
Q80347919Management and therapy of dry eye disease: report of the Management and Therapy Subcommittee of the International Dry Eye WorkShop (2007)
Q34028408Managing Sjögren's Syndrome and non-Sjögren Syndrome dry eye with anti-inflammatory therapy.
Q47442388Modern Therapeutic Approaches for Noninfectious Ocular Diseases Involving Inflammation.
Q35799409Modulation of HLA-DR in dry eye patients following 30 days of treatment with a lubricant eyedrop solution
Q62398521Mucosal Immunity and Self-Tolerance in the Ocular Surface System
Q38058002New agents for treating dry eye syndrome.
Q79537020New insights into the diagnosis and treatment of dry eye
Q28238074Nocturnal lagophthalmos: an overview and classification
Q34730735Ocular allergy guidelines: a practical treatment algorithm
Q36068686Ocular pharmacokinetics and safety of ciclosporin, a novel topical treatment for dry eye.
Q81551290Ocular surface and tear functions after topical cyclosporine treatment in dry eye patients with chronic graft-versus-host disease
Q52608828Patient and physician perspectives on the use of cyclosporine ophthalmic emulsion 0.05% for the management of chronic dry eye.
Q61808996Patient-reported severity of dry eye and quality of life in diabetes
Q40114745Pharmacokinetic-Pharmacodynamic Modeling to Study the Antipyretic Effect of Qingkailing Injection on Pyrexia Model Rats
Q37079081Pharmacological management of dry eye in the elderly patient
Q37826752Pharmacotherapy of dry eye.
Q91905513Practical guidance for the use of cyclosporine ophthalmic solutions in the management of dry eye disease
Q36569538Randomized, Multicenter, Double-Blind Study of the Safety and Efficacy of 1%D-3-Hydroxybutyrate eye drops for Dry Eye Disease
Q37610134Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome.
Q36168688Recent advances in the management of ocular complications of Sjögren's syndrome
Q36478996Reduction of quaternary ammonium-induced ocular surface toxicity by emulsions: an in vivo study in rabbits
Q52661549Reflections on Dry Eye Syndrome Treatment: Therapeutic Role of Blood Products.
Q34325595Short-term effects of topical cyclosporine A 0.05% (Restasis) in long-standing prosthetic eye wearers: a pilot study
Q38076070Sjögren's syndrome in older patients: aetiology, diagnosis and management
Q38171801Systematic review of randomised clinical trials on topical ciclosporin A for the treatment of dry eye disease.
Q35589996Systemic cyclosporin A in high failure risk, repeated corneal transplantation
Q36864045The Effect of Autologous Platelet Lysate Eye Drops: An In Vivo Confocal Microscopy Study
Q36039088The IMPACT study: a prospective evaluation of the effects of cyclosporine ophthalmic emulsion 0.05% on ocular surface staining and visual performance in patients with dry eye
Q38925320The Use of Cyclosporine A in Rheumatology: a 2016 Comprehensive Review
Q44600963The comparison of efficacies of topical corticosteroids and nonsteroidal anti-inflammatory drops on dry eye patients: a clinical and immunocytochemical study
Q50480678The efficacy of topical 0.05 % cyclosporine A in patients with dry eye disease associated with Sjögren's syndrome.
Q38270449The role and treatment of inflammation in dry eye disease
Q43171662The therapeutic effect of DA-6034 on ocular inflammation via suppression of MMP-9 and inflammatory cytokines and activation of the MAPK signaling pathway in an experimental dry eye model
Q34391944The treatment of dry eye.
Q44498935Topical and systemic medications for the treatment of primary Sjögren's syndrome.
Q24670344Topical ciclosporin in the treatment of ocular surface disorders
Q44548621Topical cyclosporine A 0.5% as a possible new treatment for superior limbic keratoconjunctivitis
Q84735553Topical cyclosporine A for the dry eye findings of thyroid orbitopathy patients
Q90093016Topical cyclosporine A therapy for dry eye syndrome
Q35087001Topical cyclosporine a for treatment of dry eye due to chronic mustard gas injury
Q36009560Topical fluorometholone treatment for ocular dryness in patients with Sjögren syndrome: a randomized clinical trial in China
Q24188132Topical treatments for blepharokeratoconjunctivitis in children
Q38760378Topical treatments for blepharokeratoconjunctivitis in children.
Q36056942Treating Sjögren's Syndrome: Insights for the Clinician
Q37236096Treatment of chronic dry eye: focus on cyclosporine
Q30249011Treatment of primary Sjögren syndrome
Q44203592Trehalose eye drops in the treatment of dry eye syndrome
Q94466109[The dry eye. Current concepts on classification, diagnostics, and pathogenesis]

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