Enzymatically degraded low density lipoproteins are more potent inducers of egr-1 mRNA than oxidized or native low density lipoproteins

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Enzymatically degraded low density lipoproteins are more potent inducers of egr-1 mRNA than oxidized or native low density lipoproteins is …
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scholarly articleQ13442814

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P356DOI10.1016/S0009-9120(01)00258-2
P698PubMed publication ID11676978

P2093author name stringArmstrong VW
Wieland E
Tesch A
Stoyanova E
P2860cites workLocalization of tissue factor in the normal vessel wall and in the atherosclerotic plaqueQ24339425
The response-to-retention hypothesis of early atherogenesisQ24629974
Atherosclerosis — An Inflammatory DiseaseQ26776972
NF-kappaB: pivotal mediator or innocent bystander in atherogenesis?Q28346544
Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stressQ28512203
THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUMQ29391553
Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formationQ33850346
High-level expression of Egr-1 and Egr-1-inducible genes in mouse and human atherosclerosis.Q33939860
LPS induction of gene expression in human monocytesQ34189313
On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moietyQ36365606
Transcriptional regulation of the Icam-1 gene in antigen receptor- and phorbol ester-stimulated B lymphocytes: role for transcription factor EGR1.Q36366454
The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineageQ38322297
Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosisQ40137011
The role of oxidized lipoproteins in atherogenesisQ41043422
Copper and cell-oxidized low-density lipoprotein induces activator protein 1 in fibroblasts, endothelial and smooth muscle cellsQ41104341
Fc gamma R-dependent mitogen-activated protein kinase activation in leukocytes: a common signal transduction event necessary for expression of TNF-alpha and early activation genesQ41169343
Receptor-specific uptake and degradation of acetylated, oxidized and native LDL in the human monocytic Mono Mac 6sr cell lineQ41454508
Inducible expression of Egr-1-dependent genes. A paradigm of transcriptional activation in vascular endotheliumQ41604083
Aggregated low density lipoprotein induces and enters surface-connected compartments of human monocyte-macrophages. Uptake occurs independently of the low density lipoprotein receptorQ41927188
Hypoxia-associated induction of early growth response-1 gene expressionQ42472170
Enzymatically Degraded, Nonoxidized LDL Induces Human Vascular Smooth Muscle Cell Activation, Foam Cell Transformation, and ProliferationQ62658891
Lipoproteins induce expression of the early growth response gene-1 in vascular smooth muscle cells from ratQ70688016
Egr-1-induced endothelial gene expression: a common theme in vascular injuryQ70990718
Native and oxidized low density lipoprotein induction of tissue factor gene expression in smooth muscle cells is mediated by both Egr-1 and Sp1Q73157333
Complement activation by oxidatively modified low-density lipoproteinsQ73231518
Oxidized low density lipoprotein and very low density lipoprotein enhance expression of monocyte chemoattractant protein-1 in rabbit peritoneal exudate macrophagesQ73589896
Dysregulation of monocytic nuclear factor-kappa B by oxidized low-density lipoproteinQ73832871
Enzymatically degraded LDL preferentially binds to CD14(high) CD16(+) monocytes and induces foam cell formation mediated only in part by the class B scavenger-receptor CD36Q73991485
Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesionQ74351422
Atherogenic properties of enzymatically degraded LDL: selective induction of MCP-1 and cytotoxic effects on human macrophagesQ77318962
Constitutive protein expression of monocyte chemotactic protein-1 (MCP-1) by myelomonocytic cell lines and regulation of the secretion by anti- and proinflammatory stimuliQ78214518
P433issue6
P921main subjectlipoproteinQ28350
P304page(s)483-490
P577publication date2001-09-01
P1433published inClinical BiochemistryQ5133749
P1476titleEnzymatically degraded low density lipoproteins are more potent inducers of egr-1 mRNA than oxidized or native low density lipoproteins
P478volume34

Reverse relations

Q39585678Hypochlorite-modified high-density lipoprotein promotes induction of HO-1 in endothelial cells via activation of p42/44 MAPK and zinc finger transcription factor Egr-1.cites workP2860

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