CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice.

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CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/ATVBAHA.115.306347
P932PMC publication ID4850098
P698PubMed publication ID26988592

P50authorYacine BoulaftaliQ58417243
Caterina CasariQ59696713
P2093author name stringWolfgang Bergmeier
Pamela B Conley
Nigel Mackman
David S Paul
Raymond Piatt
A Phillip Owens
Robert H Lee
Ashley Beale
P2860cites workA definition of the intima of human arteries and of its atherosclerosis-prone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart AssociationQ67731786
Platelet activation in unstable coronary diseaseQ68903080
Structure and function of rap proteins in human plateletsQ72202411
Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery diseaseQ74172108
Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromesQ78108701
Platelet P-selectin facilitates atherosclerotic lesion developmentQ78654773
Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivoQ80543349
Calcium-diacylglycerol guanine nucleotide exchange factor I gene mutations associated with loss of function in canine plateletsQ80682832
Human CalDAG-GEFI gene (RASGRP2) mutation affects platelet function and causes severe bleedingQ24299751
CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formationQ28118463
Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular diseaseQ28195300
Changes in platelet P-selectin and in plasma C-reactive protein in acute atherosclerotic ischemic stroke treated with a loading dose of clopidogrelQ28195775
Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectinQ28512587
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.Q30310323
Platelet-neutrophil-interactions: linking hemostasis and inflammationQ30441637
Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.Q30479426
The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapyQ30498119
Rap1b is required for normal platelet function and hemostasis in miceQ33778323
CalDAG-GEFI and platelet activationQ33993417
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivoQ36370457
CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin alphaIIbbeta3 in plateletsQ36843696
Platelet factor 4 mediates vascular smooth muscle cell injury responsesQ36873325
Absence of P-selectin delays fatty streak formation in miceQ37364649
Platelet-derived chemokines in vascular remodeling and atherosclerosisQ37736336
Platelets: key players in vascular inflammationQ38038134
A critical role of platelet adhesion in the initiation of atherosclerotic lesion formationQ41824616
CalDAG-GEFI is at the nexus of calcium-dependent platelet activation.Q45921416
Clopidogrel attenuates atheroma formation and induces a stable plaque phenotype in apolipoprotein E knockout miceQ46073339
Platelet adhesion via glycoprotein IIb integrin is critical for atheroprogression and focal cerebral ischemia: an in vivo study in mice lacking glycoprotein IIb.Q46652724
High neutrophil numbers in human carotid atherosclerotic plaques are associated with characteristics of rupture-prone lesions.Q51555647
Clopidogrel significantly lowers the development of atherosclerosis in ApoE-deficient mice in vivo.Q53471537
Roles of purinergic receptor P2Y, G protein-coupled 12 in the development of atherosclerosis in apolipoprotein E-deficient mice.Q54308259
Vessel wall, not platelet, P2Y12 potentiates early atherogenesisQ61668952
Platelet activity in vivo in hyperlipoproteinemia--importance of combined hyperlipidemiaQ61684245
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P304page(s)792-799
P577publication date2016-03-17
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476titleCalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice
P478volume36

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cites work (P2860)
Q49960669Dual Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease and Peripheral Artery Disease Patients
Q39155496Integrin signaling in atherosclerosis.
Q41910005Losing your GRP on platelet activation
Q90480284Phenotype analysis and clinical management in a large family with a novel truncating mutation in RASGRP2, the CalDAG-GEFI encoding gene
Q52644169Platelet Signaling Pathways and New Inhibitors.
Q90403621Platelets Are at the Nexus of Vascular Diseases
Q54977187RAP GTPases and platelet integrin signaling.
Q89633631RasGRP2 Structure, Function and Genetic Variants in Platelet Pathophysiology
Q57818443Reporting Sex and Sex Differences in Preclinical Studies
Q57287894The role of P2Y receptor in ischemic stroke of atherosclerotic origin
Q50115928Translational Implications of Platelets as Vascular First Responders

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