Structural domains of agrin required for clustering of nicotinic acetylcholine receptors.

scientific article

Structural domains of agrin required for clustering of nicotinic acetylcholine receptors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/J.1460-2075.1994.TB06575.X
P932PMC publication ID395162
P698PubMed publication ID8026466

P2093author name stringScheller RH
Harrison S
Campanelli JT
Hoch W
P2860cites workDevelopmental expression and alternative splicing of chick agrin RNA.Q42508242
Agrin-induced specializations contain cytoplasmic, membrane, and extracellular matrix-associated components of the postsynaptic apparatusQ46210656
The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycansQ46736156
Agrin induces phosphorylation of the nicotinic acetylcholine receptorQ67692148
The putative agrin receptor binds ligand in a calcium-dependent manner and aggregates during agrin-induced acetylcholine receptor clusteringQ68265156
Heparin and heparan sulfate partially inhibit induction of acetylcholine receptor accumulation by nerve in Xenopus cultureQ69302484
Basement membrane glycoprotein laminin binds to heparinQ72862128
Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition methodQ24631695
Structure and expression of a rat agrinQ28281895
Agrin mediates cell contact-induced acetylcholine receptor clusteringQ30812710
cDNA that encodes active agrinQ31160427
The agrin gene codes for a family of basal lamina proteins that differ in function and distributionQ34234963
Identification of agrin, a synaptic organizing protein from Torpedo electric organQ36217149
The agrin hypothesisQ37577094
Protein oligomerization in the endoplasmic reticulumQ38737584
Effects of innervation on the distribution of acetylcholine receptors on cultured muscle cellsQ39445259
28 Cell fusionQ40212366
Functions of agrin and agrin-related proteinsQ40485308
Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions.Q41083959
Inhibition of agrin-induced acetylcholine-receptor aggregation by heparin, heparan sulfate, and other polyanionsQ41137761
Developmental regulation of highly active alternatively spliced forms of agrinQ41528859
RNA splicing regulates agrin-mediated acetylcholine receptor clustering activity on cultured myotubesQ42451366
The agrin receptor. Localization in the postsynaptic membrane, interaction with agrin, and relationship to the acetylcholine receptorQ42502295
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)2814-2821
P577publication date1994-06-01
P1433published inThe EMBO JournalQ1278554
P1476titleStructural domains of agrin required for clustering of nicotinic acetylcholine receptors
P478volume13

Reverse relations

cites work (P2860)
Q36255897A functional role for specific spliced variants of the alpha7beta1 integrin in acetylcholine receptor clustering
Q24302188A single pulse of agrin triggers a pathway that acts to cluster acetylcholine receptors
Q36382434Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site
Q71574134Aggregation of sodium channels induced by a postnatally upregulated isoform of agrin
Q28280777Agrin acts via a MuSK receptor complex
Q51423883Agrin controls synaptic differentiation in hippocampal neurons.
Q28565033Agrin induced morphological and structural changes in growth cones of cultured hippocampal neurons
Q35787956Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.
Q24314924Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane
Q41212392Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptor
Q28574863Alternative splicing of agrin regulates its binding to heparin alpha-dystroglycan, and the cell surface
Q28513062Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction
Q28569020Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK
Q38652862Diverse roles for glycosaminoglycans in neural patterning.
Q37353218Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy.
Q41686895Evidence of an agrin receptor in cortical neurons
Q28344242Expression of agrin, dystroglycan, and utrophin in normal renal tissue and in experimental glomerulopathies
Q38494033Functional innervation of cultured human skeletal muscle proceeds by two modes with regard to agrin effects
Q50131806Fundamental Molecules and Mechanisms for Forming and Maintaining Neuromuscular Synapses.
Q33534464Immunoscreening of the extracellular proteome of colorectal cancer cells
Q28206352Induction, assembly, maturation and maintenance of a postsynaptic apparatus
Q64979512Influencing Early Stages of Neuromuscular Junction Formation through Glycocalyx Engineering.
Q37543699Interactions between heparan sulfate and proteins-design and functional implications
Q74023755Intracellular calcium regulates agrin-induced acetylcholine receptor clustering
Q34282459LG/LNS domains: multiple functions -- one business end?
Q36696606LG2 agrin mutation causing severe congenital myasthenic syndrome mimics functional characteristics of non-neural (z-) agrin.
Q39684149Modulating the function of the measles virus RNA-dependent RNA polymerase by insertion of green fluorescent protein into the open reading frame
Q48229331Motor neuronal repletion of the NMJ organizer, Agrin, modulates the severity of the spinal muscular atrophy disease phenotype in model mice
Q91588676Myasthenia Gravis: Pathogenic Effects of Autoantibodies on Neuromuscular Architecture
Q41191577Neural agrin activates a high-affinity receptor in C2 muscle cells that is unresponsive to muscle agrin.
Q42442651Neural agrin induces ectopic postsynaptic specializations in innervated muscle fibers.
Q36663472Neural agrin: a synaptic stabiliser.
Q35097331New insights into the roles of agrin
Q47119978Novel SEA and LG2 Agrin mutations causing congenital Myasthenic syndrome
Q41137370Rapsyn and agrin slow the metabolic degradation of the acetylcholine receptor
Q28510134Regulated expression of the proteoglycan SPOCK in the neuromuscular system
Q41541455Sequential roles of agrin, MuSK and rapsyn during neuromuscular junction formation
Q43581716Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors.
Q38062321Structural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation.
Q78166015Synapse formation molecules in muscle and autonomic ganglia: the dual constraint hypothesis
Q28564406The COOH-terminal domain of agrin signals via a synaptic receptor in central nervous system neurons
Q48389780The role of alternative splicing in regulating agrin binding to muscle cells
Q34698918The zebrafish ennui behavioral mutation disrupts acetylcholine receptor localization and motor axon stability.
Q41017902alpha-Dystroglycan functions in acetylcholine receptor aggregation but is not a coreceptor for agrin-MuSK signaling.

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