| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1004453955 |
| P356 | DOI | 10.1038/35082088 |
| P698 | PubMed publication ID | 11418861 |
| P5875 | ResearchGate publication ID | 232777351 |
| P50 | author | David Julius | Q1174906 |
| Moses V. Chao | Q37378122 | ||
| P2093 | author name string | Kong H | |
| Basbaum AI | |||
| Shields S | |||
| Chuang HH | |||
| Jordt SE | |||
| Prescott ED | |||
| P2860 | cites work | Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol | Q22001504 |
| The capsaicin receptor: a heat-activated ion channel in the pain pathway | Q24322558 | ||
| Induction of vanilloid receptor channel activity by protein kinase C | Q28141740 | ||
| Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia | Q28144926 | ||
| Regulation of Drosophila transient receptor potential-like (TrpL) channels by phospholipase C-dependent mechanisms | Q28345412 | ||
| Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide | Q28370516 | ||
| Impaired nociception and pain sensation in mice lacking the capsaicin receptor | Q28511370 | ||
| The cloned capsaicin receptor integrates multiple pain-producing stimuli | Q29547511 | ||
| Neuronal plasticity: increasing the gain in pain | Q29615421 | ||
| Neurotrophins and hyperalgesia. | Q33679514 | ||
| The changing sensitivity in the life of the nociceptor | Q33735075 | ||
| From worm to man: three subfamilies of TRP channels | Q33863116 | ||
| Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. | Q33890263 | ||
| Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses | Q34060592 | ||
| Acid potentiation of the capsaicin receptor determined by a key extracellular site | Q35177598 | ||
| Phenotypic modification of primary sensory neurons: the role of nerve growth factor in the production of persistent pain | Q41055368 | ||
| Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma | Q42544747 | ||
| Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses | Q46057937 | ||
| Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex | Q47070308 | ||
| Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions | Q48906142 | ||
| Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner. | Q50518013 | ||
| Do phosphatidylinositides modulate vertebrate phototransduction? | Q50719758 | ||
| Specific Involvement of PKC-ε in Sensitization of the Neuronal Response to Painful Heat | Q58792194 | ||
| Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin | Q60705124 | ||
| Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture | Q69357253 | ||
| Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells | Q77348315 | ||
| Neutralization of endogenous NGF prevents the sensitization of nociceptors supplying inflamed skin | Q77363273 | ||
| Nerve growth factor evokes hyperalgesia in mice lacking the low-affinity neurotrophin receptor p75 | Q77623877 | ||
| P433 | issue | 6840 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 957-962 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition | |
| P478 | volume | 411 |
| Q35859770 | 17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception. |
| Q36976409 | 17beta-estradiol activates estrogen receptor beta-signalling and inhibits transient receptor potential vanilloid receptor 1 activation by capsaicin in adult rat nociceptor neurons |
| Q44919605 | 2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. |
| Q44232804 | A cold- and menthol-activated current in rat dorsal root ganglion neurones: properties and role in cold transduction. |
| Q44939729 | A developmental switch in acute sensitization of small dorsal root ganglion (DRG) neurons to capsaicin or noxious heating by NGF. |
| Q58610880 | A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine |
| Q53363192 | A key role for gp130 expressed on peripheral sensory nerves in pathological pain. |
| Q44452050 | A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity |
| Q33432568 | A phospholipid sensor controls mechanogating of the K+ channel TREK-1. |
| Q24297948 | A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1 |
| Q42161635 | A scalable synthesis of the IP7 isomer, 5-PP-Ins(1,2,3,4,6)P5. |
| Q36710217 | A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating |
| Q35075369 | A-kinase anchoring protein 150 mediates transient receptor potential family V type 1 sensitivity to phosphatidylinositol-4,5-bisphosphate |
| Q28509578 | ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures |
| Q37610249 | Acid-sensing ion channels and pain: therapeutic potential? |
| Q35047663 | Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels |
| Q24671891 | Activation and sensitisation of the vanilloid receptor: role in gastrointestinal inflammation and function |
| Q30501036 | Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats |
| Q36439922 | Activation of Ca(2+) -activated Cl(-) channel ANO1 by localized Ca(2+) signals |
| Q93126054 | Activation of Kv7 Potassium Channels Inhibits Intracellular Ca2+ Increases Triggered By TRPV1-Mediated Pain-Inducing Stimuli in F11 Immortalized Sensory Neurons |
| Q41865958 | Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia |
| Q35766327 | Activation of TRPV1 by capsaicin induces functional kinin B(1) receptor in rat spinal cord microglia |
| Q34112727 | Activation of a TRP-like channel and intracellular Ca2+ dynamics during phospholipase-C-mediated cell death. |
| Q44666574 | Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice |
| Q40578135 | Activation of human TRPC6 channels by receptor stimulation |
| Q50915678 | Activation of rat transient receptor potential cation channel subfamily V member 1 channels by 2-aminoethoxydiphenyl borate. |
| Q46612877 | Activation of transient receptor potential vanilloid 1 (TRPV1) by resiniferatoxin |
| Q31125580 | Activation of vanilloid receptor 1 by resiniferatoxin mobilizes calcium from inositol 1,4,5-trisphosphate-sensitive stores |
| Q35111262 | Activity and Ca²⁺ regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons |
| Q42088711 | Activity of the neuronal cold sensor TRPM8 is regulated by phospholipase C via the phospholipid phosphoinositol 4,5-bisphosphate. |
| Q35172477 | After a decade of intravesical vanilloid therapy: still more questions than answers |
| Q46583935 | Airway expression of Transient Receptor Potential (TRP) Vanniloid-1 and Ankyrin-1 channels is not increased in patients with Idiopathic Pulmonary Fibrosis. |
| Q35050518 | Airway neural plasticity: the nerves they are a-changin'. |
| Q39104064 | Altered expression of TRPV1 and sensitivity to capsaicin in pulmonary myelinated afferents following chronic airway inflammation in the rat. |
| Q39970967 | Altered pharmacology of native rodent spinal cord TRPV1 after phosphorylation |
| Q86536350 | Ambient temperature affects the temperature threshold for TRPM8 activation through interaction of phosphatidylinositol 4,5-bisphosphate |
| Q24551151 | Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors |
| Q36068723 | An HSV-based library screen identifies PP1α as a negative TRPV1 regulator with analgesic activity in models of pain |
| Q40539024 | An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels |
| Q24534526 | An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors |
| Q37511848 | Analgesic targets: today and tomorrow |
| Q33947159 | Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels |
| Q37568663 | Anandamide and the vanilloid receptor (TRPV1). |
| Q24672354 | Anandamide and vanilloid TRPV1 receptors |
| Q39652985 | Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro |
| Q45188902 | Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis. |
| Q37593191 | Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity |
| Q37362045 | Anoctamin 1 mediates thermal pain as a heat sensor |
| Q35064559 | Antagonism of nerve growth factor-TrkA signaling and the relief of pain |
| Q26746194 | Anti-nerve growth factor in pain management: current evidence |
| Q35098782 | Antinociceptive activity of methanolic extract of Muntingia calabura leaves: further elucidation of the possible mechanisms |
| Q42254334 | Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder |
| Q35536969 | Antitussive activity of iodo-resiniferatoxin in guinea pigs |
| Q37041620 | Artemin, a glial cell line-derived neurotrophic factor family member, induces TRPM8-dependent cold pain |
| Q37343885 | Atropine-enhanced, antigen challenge-induced airway hyperreactivity in guinea pigs is mediated by eosinophils and nerve growth factor |
| Q35060436 | B-type natriuretic peptide-induced delayed modulation of TRPV1 and P2X3 receptors of mouse trigeminal sensory neurons |
| Q37027321 | Basic mechanisms of cough: current understanding and remaining questions |
| Q33783684 | Behavioral evidence of thermal hyperalgesia and mechanical allodynia induced by intradermal cinnamaldehyde in rats. |
| Q36725869 | Binding and direct activation of the epithelial Na+ channel (ENaC) by phosphatidylinositides. |
| Q41867655 | Biological constraints limit the use of rapamycin-inducible FKBP12-Inp54p for depleting PIP2 in dorsal root ganglia neurons |
| Q45275653 | Biphasic currents evoked by chemical or thermal activation of the heat-gated ion channel, TRPV3. |
| Q36404487 | Bradykinin and peripheral sensitization |
| Q46681381 | Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission. |
| Q34099431 | Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia. |
| Q28582515 | Bradykinin-induced functional competence and trafficking of the delta-opioid receptor in trigeminal nociceptors |
| Q37328247 | Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control |
| Q47785613 | Burn Pain: A Systematic and Critical Review of Epidemiology, Pathophysiology, and Treatment. |
| Q38193083 | Calcitonin gene-related peptide is a key neurotransmitter in the neuro-immune axis |
| Q38175134 | Calcium-permeable ion channels in pain signaling |
| Q40367630 | Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. |
| Q48952905 | Can receptor potentials be detected with threshold tracking in rat cutaneous nociceptive terminals? |
| Q38269376 | Cannabinoids: new promising agents in the treatment of neurological diseases |
| Q44483306 | Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. |
| Q26744369 | Capsaicin, Nociception and Pain |
| Q37381098 | Capsaicin-evoked iCGRP release from human dental pulp: a model system for the study of peripheral neuropeptide secretion in normal healthy tissue |
| Q93080654 | Capsaicin: Effects on the Pathogenesis of Hepatocellular Carcinoma |
| Q92434547 | Capsaicin: Physicochemical properties, cutaneous reactions and potential applications in painful and inflammatory conditions |
| Q29011961 | Cellular and Molecular Mechanisms of Pain |
| Q42165817 | Changes in osmolality sensitize the response to capsaicin in trigeminal sensory neurons |
| Q37732004 | Channelopathies linked to plasma membrane phosphoinositides. |
| Q82028768 | Chapter 16 Pathological changes in the nociceptor: alterations in TRPV1 activity and expression |
| Q38447914 | Characterization of skin inflammation induced by repeated exposure of toluene, xylene, and formaldehyde in mice |
| Q36493629 | Charge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels |
| Q24683873 | Chemokines and the pathophysiology of neuropathic pain |
| Q36285939 | Chemokines: integrators of pain and inflammation |
| Q34807572 | Chronic alteration in phosphatidylinositol 4,5-biphosphate levels regulates capsaicin and mustard oil responses. |
| Q42287164 | Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk |
| Q40379392 | Co-activation of P2Y2 receptor and TRPV channel by ATP: implications for ATP induced pain |
| Q45357056 | Coding and Plasticity in the Mammalian Thermosensory System |
| Q38126171 | Conserved systems and functional genomic assessment of nociception. |
| Q37347537 | Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists |
| Q58766601 | Constitutive activity of transient receptor potential vanilloid type 1 triggers spontaneous firing in nerve growth factor-treated dorsal root ganglion neurons of rats |
| Q34510177 | Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception |
| Q28068037 | Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways |
| Q28571463 | Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel |
| Q41788994 | Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice. |
| Q43443338 | Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats |
| Q35044549 | Controlling calcium entry. |
| Q39298750 | Cough reflex hypersensitivity: A role for neurotrophins |
| Q35676212 | Cough. 5: The type 1 vanilloid receptor: a sensory receptor for cough |
| Q35496529 | Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation |
| Q38245673 | Cross-talk between neural and immune receptors provides a potential mechanism of homeostatic regulation in the gut mucosa. |
| Q34173925 | Cutaneous C-polymodal fibers lacking TRPV1 are sensitized to heat following inflammation, but fail to drive heat hyperalgesia in the absence of TPV1 containing C-heat fibers |
| Q37351994 | Cytokine and chemokine regulation of sensory neuron function. |
| Q44012273 | Delta 9-tetrahydrocannabinol and cannabinol activate capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism. |
| Q36512392 | Dense transient receptor potential cation channel, vanilloid family, type 2 (TRPV2) immunoreactivity defines a subset of motoneurons in the dorsal lateral nucleus of the spinal cord, the nucleus ambiguus and the trigeminal motor nucleus in rat. |
| Q47706869 | Depolarizing Effectors of Bradykinin Signaling in Nociceptor Excitation in Pain Perception |
| Q42501979 | Desensitization of cold- and menthol-sensitive rat dorsal root ganglion neurones by inflammatory mediators. |
| Q35858432 | Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery. |
| Q30483485 | Determinants of molecular specificity in phosphoinositide regulation. Phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) is the endogenous lipid regulating TRPV1. |
| Q92535035 | Developing Modern Pain Therapies |
| Q34097606 | Differential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitors |
| Q30303099 | Differential regulation of GnRH secretion in the preoptic area (POA) and the median eminence (ME) in male mice |
| Q28544410 | Differential regulation of proton-sensitive ion channels by phospholipids: a comparative study between ASICs and TRPV1 |
| Q44835134 | Direct interaction of adenosine with the TRPV1 channel protein. |
| Q40746070 | Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues |
| Q58572799 | Dissecting the Physiology and Pathophysiology of Glucagon-Like Peptide-1 |
| Q34634374 | Dissection of the components for PIP2 activation and thermosensation in TRP channels |
| Q41087240 | Distinct calcitonin gene-related peptide expression pattern in primary afferents contribute to different neuropathic symptoms following chronic constriction or crush injuries to the rat sciatic nerve |
| Q40102049 | Distinct modulations of human capsaicin receptor by protons and magnesium through different domains |
| Q37048101 | Distinctive changes in plasma membrane phosphoinositides underlie differential regulation of TRPV1 in nociceptive neurons. |
| Q34467077 | Distinctive features of Trk neurotrophin receptor transactivation by G protein-coupled receptors. |
| Q37417929 | Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold |
| Q60705113 | Diversity of neurotrophin action in the postnatal spinal cord |
| Q60705115 | Does NGF binding to p75 and trkA receptors activate independent signalling pathways to sensitize nociceptors? |
| Q46843635 | Downregulation of transient receptor potential melastatin 8 by protein kinase C-mediated dephosphorylation. |
| Q40114487 | Dual regulation of TRPV1 by phosphoinositides. |
| Q44200822 | Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P2. |
| Q36692733 | Dynamic expression of neurotrophic factor receptors in postnatal spinal motoneurons and in mouse model of ALS |
| Q38845964 | Effect of a bradykinin-potentiating factor isolated from scorpion venom (Leiurus quinquestriatus) on some blood indices and lipid profile in irradiated rats |
| Q53414076 | Effect of botulinum toxin on expression of nerve growth factor and transient receptor potential vanilloid 1 in urothelium and detrusor muscle of rats with bladder outlet obstruction-induced detrusor overactivity. |
| Q42562953 | Effect of protease-activated receptor 2 activation on single TRPV1 channel activities in rat vagal pulmonary sensory neurons. |
| Q46719338 | Effects of TRPA1 agonists mustard oil and cinnamaldehyde on lumbar spinal wide-dynamic range neuronal responses to innocuous and noxious cutaneous stimuli in rats |
| Q39456171 | Effects of the TRPV1 antagonist ABT-102 on body temperature in healthy volunteers: pharmacokinetic/ pharmacodynamic analysis of three phase 1 trials. |
| Q36931658 | Emerging drugs for osteoarthritis |
| Q42972027 | Emodin down-regulates expression of TRPV1 mRNA and its function in DRG neurons in vitro |
| Q46607378 | Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model |
| Q40388693 | Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonists |
| Q40052077 | Endothelin potentiates TRPV1 via ETA receptor-mediated activation of protein kinase C. |
| Q42457403 | Enhancement of potency and efficacy of NADA by PKC-mediated phosphorylation of vanilloid receptor |
| Q42319532 | Evodiamine suppresses capsaicin-induced thermal hyperalgesia through activation and subsequent desensitization of the transient receptor potential V1 channels |
| Q37461000 | Excitation and sensitization of nociceptors by bradykinin: what do we know? |
| Q28567269 | Excitatory monocyte chemoattractant protein-1 signaling is up-regulated in sensory neurons after chronic compression of the dorsal root ganglion |
| Q44495444 | Experiments to test the role of phosphatidylinositol 4,5-bisphosphate in neurotransmitter-induced M-channel closure in bullfrog sympathetic neurons. |
| Q57297148 | Exploring Morphine-Triggered PKC-Targets and Their Interaction with Signaling Pathways Leading to Pain via TrkA |
| Q41549788 | Expression and Purification of the Pain Receptor TRPV1 for Spectroscopic Analysis |
| Q40408220 | Expression and characterization of the intracellular vanilloid receptor (TRPV1) in bronchi from patients with chronic cough |
| Q46814674 | Expression of capsaicin receptor TRPV-1 in synovial tissues of patients with symptomatic internal derangement of the temporomandibular joint and joint pain |
| Q46510733 | Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling. |
| Q46155875 | Extracellular pH and neuronal depolarization serve as dynamic switches to rapidly mobilize trkA to the membrane of adult sensory neurons. |
| Q41333087 | Facial pain induces the alteration of transient receptor potential vanilloid receptor 1 expression in rat trigeminal ganglion |
| Q44436412 | Fast Ca2+-induced potentiation of heat-activated ionic currents requires cAMP/PKA signaling and functional AKAP anchoring. |
| Q78045520 | Feeling below PAR: proteinase-activated receptors and the perception of neuroinflammatory pain |
| Q73435159 | From TRPs to SOCs, CCEs, and CRACs: consensus and controversies |
| Q36913317 | From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs |
| Q38185070 | From genes to pain: nerve growth factor and hereditary sensory and autonomic neuropathy type V. |
| Q30477216 | Frontiers in pruritus research: scratching the brain for more effective itch therapy |
| Q37473155 | Function and regulation of TRP family channels in C. elegans |
| Q35522364 | Functional abdominal pain. |
| Q36134913 | Functional aspects and mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia |
| Q40457196 | Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate. |
| Q40423723 | Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate. |
| Q28582473 | Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1 |
| Q26865131 | Functionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational data |
| Q37683369 | Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel |
| Q40689798 | GFR alpha2/neurturin signalling regulates noxious heat transduction in isolectin B4-binding mouse sensory neurons |
| Q48189370 | Gastrin-releasing peptide acts via postsynaptic BB2 receptors to modulate inward rectifier K+ and TRPV1-like conductances in rat paraventricular thalamic neurons. |
| Q28654816 | Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins |
| Q36119232 | Gating of TRP channels: a voltage connection? |
| Q36817045 | Gene therapy applications for the treatment of neuropathic pain |
| Q42775107 | Group III metabotropic glutamate receptors and transient receptor potential vanilloid 1 co-localize and interact on nociceptors |
| Q47276590 | H89 dihydrochloride hydrate and calphostin C lower the body temperature through TRPV1. |
| Q39377629 | Heat shock factor 1 regulates the expression of the TRPV1 gene in the rat preoptic-anterior hypothalamus area during lipopolysaccharide-induced fever |
| Q34399176 | How best to fight that nasty itch - from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches. |
| Q40808983 | How does rhinovirus cause the common cold cough? |
| Q39257750 | Human sensory neuron-specific Mas-related G protein-coupled receptors-X1 sensitize and directly activate transient receptor potential cation channel V1 via distinct signaling pathways |
| Q34150866 | Human sensory neurons: Membrane properties and sensitization by inflammatory mediators |
| Q35049073 | Hydrogen sulfide causes vanilloid receptor 1-mediated neurogenic inflammation in the airways |
| Q36678502 | Hydrolysis of phosphatidylinositol 4,5-bisphosphate mediates calcium-induced inactivation of TRPV6 channels. |
| Q37368695 | Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat |
| Q42074359 | IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex |
| Q33195593 | Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist. |
| Q28252141 | Identification of a G protein-coupled receptor specifically responsive to beta-alanine |
| Q28580334 | Identification of a cold receptor reveals a general role for TRP channels in thermosensation |
| Q34869655 | Identification of a tetrameric assembly domain in the C terminus of heat-activated TRPV1 channels. |
| Q44763072 | Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. |
| Q55506553 | Inactivation of Anandamide Signaling: A Continuing Debate. |
| Q48143196 | Increased hyperpolarized [1-13 C] lactate production in a model of joint inflammation is not accompanied by tissue acidosis as assessed using hyperpolarized 13 C-labelled bicarbonate |
| Q37067666 | Increases in transient receptor potential vanilloid-1 mRNA and protein in primary afferent neurons stimulated by protein kinase C and their possible role in neurogenic inflammation |
| Q90614329 | Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms |
| Q36089198 | Inflammation-induced hyperexcitability of nociceptive gastrointestinal DRG neurones: the role of voltage-gated ion channels |
| Q36831604 | Inflammatory and neuropathic cold allodynia are selectively mediated by the neurotrophic factor receptor GFRα3 |
| Q36734927 | Inflammatory mediators modulating the transient receptor potential vanilloid 1 receptor: therapeutic targets to treat inflammatory and neuropathic pain |
| Q37211785 | Inflammatory pain: the cellular basis of heat hyperalgesia. |
| Q34295806 | Inflammatory signals enhance piezo2-mediated mechanosensitive currents |
| Q36509492 | Influence of TRPV1 on diabetes-induced alterations in thermal pain sensitivity |
| Q48057912 | Infrared neural stimulation induces intracellular Ca2+ release mediated by phospholipase C. |
| Q51785375 | Inhibition of M current in sensory neurons by exogenous proteases: a signaling pathway mediating inflammatory nociception. |
| Q38771733 | Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study |
| Q36110588 | Inhibition of airway hyper-responsiveness by TRPV1 antagonists (SB-705498 and PF-04065463) in the unanaesthetized, ovalbumin-sensitized guinea pig. |
| Q36487430 | Inhibition of citric acid- and capsaicin-induced cough by novel TRPV-1 antagonist, V112220, in guinea-pig |
| Q36805364 | Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate |
| Q45064242 | Inhibitory modulation of distal C-terminal on protein kinase C-dependent phospho-regulation of rat TRPV1 receptors |
| Q47838293 | Inositol triphosphate-mediated Ca2+ signals direct purinergic P2Y receptor regulation of neuronal ion channels |
| Q35915828 | Insights on TRP channels from in vivo studies in Drosophila |
| Q44658123 | Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons |
| Q26765339 | Integrating TRPV1 Receptor Function with Capsaicin Psychophysics |
| Q37234990 | Integration of thermal and osmotic regulation of water homeostasis: the role of TRPV channels |
| Q33412519 | Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor |
| Q24623493 | International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family |
| Q35600885 | International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels. |
| Q28289146 | International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels |
| Q24301233 | Intracellular Ca2+ and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5 |
| Q35163419 | Intracellular long-chain acyl CoAs activate TRPV1 channels |
| Q37144214 | Intracellular signaling in primary sensory neurons and persistent pain |
| Q83894584 | Intracellular sphingosine 1-phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons |
| Q42557696 | Intradermal administration of magnesium sulphate and magnesium chloride produces hypesthesia to mechanical but hyperalgesia to heat stimuli in humans. |
| Q44951596 | Intravesical resiniferatoxin decreases spinal c-fos expression and increases bladder volume to reflex micturition in rats with chronic inflamed urinary bladders |
| Q28283316 | Involvement of calmodulin and myosin light chain kinase in activation of mTRPC5 expressed in HEK cells |
| Q41966153 | Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis |
| Q37734810 | Ion channels and migraine |
| Q35951175 | Ion homeostasis, channels, and transporters: an update on cellular mechanisms |
| Q40019222 | Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate |
| Q50849911 | Kinin Receptors Sensitize TRPV4 Channel and Induce Mechanical Hyperalgesia: Relevance to Paclitaxel-Induced Peripheral Neuropathy in Mice. |
| Q34078781 | LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligation |
| Q35215864 | Lessons from peppers and peppermint: the molecular logic of thermosensation |
| Q92456074 | Lifting the veil on the keratinocyte contribution to cutaneous nociception |
| Q47371201 | Local Resiniferatoxin Induces Long-Lasting Analgesia in a Rat Model of Full Thickness Thermal Injury. |
| Q48397657 | Local inflammation increases vanilloid receptor 1 expression within distinct subgroups of DRG neurons |
| Q34684697 | Localization of the PIP2 sensor of TRPV1 ion channels |
| Q37322990 | Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels. |
| Q44345649 | Low-threshold heat receptor in chick sensory neurons is upregulated independently of nerve growth factor after nerve injury |
| Q60706853 | Lumbar 5 ventral root transection-induced upregulation of nerve growth factor in sensory neurons and their target tissues: a mechanism in neuropathic pain |
| Q35543110 | Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels |
| Q35687993 | Mechanisms involved in new therapies for overactive bladder. |
| Q40083297 | Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol |
| Q44545267 | Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat |
| Q36266895 | Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels |
| Q90212291 | Mechanisms underlying mechanical sensitization induced by complement C5a: the roles of macrophages, TRPV1, and calcitonin gene-related peptide receptors |
| Q39038882 | Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists |
| Q89719698 | Methanol Extract of Dicranopteris linearis Leaves Attenuate Pain via the Modulation of Opioid/NO-Mediated Pathway |
| Q35180285 | Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia |
| Q28238995 | Mode of action of cannabinoids on nociceptive nerve endings |
| Q62661272 | Modulation of TRPs by PIPs |
| Q36866983 | Modulation of cyclic nucleotide-regulated HCN channels by PIP(2) and receptors coupled to phospholipase C. |
| Q47428149 | Modulation of ion channels and synaptic transmission by a human sensory neuron-specific G-protein-coupled receptor, SNSR4/mrgX1, heterologously expressed in cultured rat neurons. |
| Q42435693 | Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators |
| Q38997049 | Molecular Pathophysiology of Congenital Long QT Syndrome |
| Q35946504 | Molecular and cellular mechanisms that initiate pain and itch |
| Q45712451 | Molecular basis for species-specific sensitivity to "hot" chili peppers |
| Q41882659 | Molecular determinants of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) binding to transient receptor potential V1 (TRPV1) channels |
| Q28216291 | Molecular mechanisms of nociception |
| Q38418532 | Molecular sensors and modulators of thermoreception. |
| Q28535638 | Monoacylglycerols activate TRPV1--a link between phospholipase C and TRPV1 |
| Q36344420 | Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons |
| Q36225080 | More than just a barrier: urothelium as a drug target for urinary bladder pain |
| Q37799398 | Moving towards supraspinal TRPV1 receptors for chronic pain relief |
| Q36144078 | Multiple roles of calmodulin and other Ca(2+)-binding proteins in the functional regulation of TRP channels |
| Q37322544 | Mustard oil enhances spinal neuronal responses to noxious heat but not cooling |
| Q42815147 | NAADP binding to its target protein in sea urchin eggs requires phospholipids |
| Q40345535 | NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. |
| Q38039856 | Nerve growth factor and Alzheimer's disease: new facts for an old hypothesis |
| Q35951416 | Nerve growth factor enhances the excitability of rat sensory neurons through activation of the atypical protein kinase C isoform, PKMζ. |
| Q28581578 | Nerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac |
| Q46419772 | Nerve growth factor modulates TRPV1 expression and function and mediates pain in chronic pancreatitis |
| Q27011486 | Nerve growth factor-mediated regulation of pain signalling and proposed new intervention strategies in clinical pain management |
| Q28069959 | Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation |
| Q45230651 | Neurotrophin-3 suppresses thermal hyperalgesia associated with neuropathic pain and attenuates transient receptor potential vanilloid receptor-1 expression in adult sensory neurons. |
| Q24678332 | Neurotrophin-regulated signalling pathways |
| Q29616108 | Neurotrophins and their receptors: a convergence point for many signalling pathways |
| Q38115263 | Neurotrophins in bladder function: what do we know and where do we go from here? |
| Q42107237 | No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex |
| Q45047535 | Nociceptin inhibits vanilloid TRPV-1-mediated neurosensitization induced by fenoterol in human isolated bronchi. |
| Q28073883 | Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies |
| Q33624465 | Nociceptive sensitization by complement C5a and C3a in mouse |
| Q42443328 | Nociceptor structural specialization in canine and rodent testicular "free" nerve endings |
| Q33625422 | Nociceptor subpopulations involved in hyperalgesic priming |
| Q24562888 | Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain |
| Q33944304 | Non-invasive diode laser activation of transient receptor potential proteins in nociceptors |
| Q34044611 | Novel Kv7.1-phosphatidylinositol 4,5-bisphosphate interaction sites uncovered by charge neutralization scanning |
| Q40019228 | Novel gating and sensitizing mechanism of capsaicin receptor (TRPV1): tonic inhibitory regulation of extracellular sodium through the external protonation sites on TRPV1. |
| Q29616107 | Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin |
| Q42843308 | Nucleotides control the excitability of sensory neurons via two P2Y receptors and a bifurcated signaling cascade. |
| Q57720655 | Octreotide inhibits capsaicin-induced activation of C and Aδ afferent fibres in rat hairy skin in vivo |
| Q34379315 | Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway |
| Q34244930 | P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation. |
| Q46455727 | PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain |
| Q44386912 | PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents |
| Q36493612 | PIP2 activates TRPV5 and releases its inhibition by intracellular Mg2+. |
| Q45242239 | PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels. |
| Q37197976 | PIP2 is a necessary cofactor for ion channel function: how and why? |
| Q44012278 | PKA/AKAP/VR-1 module: A common link of Gs-mediated signaling to thermal hyperalgesia. |
| Q42537525 | PKD2 functions as an epidermal growth factor-activated plasma membrane channel |
| Q92384478 | Pain and immunity: implications for host defence |
| Q36771715 | Paradoxic effects of propofol on visceral pain induced by various TRPV1 agonists |
| Q37282359 | Peripheral mechanisms II: the pharmacology of peripherally active antitussive drugs. |
| Q38206127 | Peripheral nerve injury modulates neurotrophin signaling in the peripheral and central nervous system |
| Q35752278 | Peripheral neural circuitry in cough |
| Q34430400 | Peripheral thermosensation in mammals |
| Q33897649 | Pharmacokinetics of the TRPV1 antagonist ABT-102 in healthy human volunteers: population analysis of data from 3 phase 1 trials |
| Q38221257 | Pharmacology of the capsaicin receptor, transient receptor potential vanilloid type-1 ion channel. |
| Q42468083 | Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. |
| Q46722172 | Phosphatidylinositol 4,5-bisphosphate rescues TRPM4 channels from desensitization. |
| Q35762279 | Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation |
| Q36295896 | Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. |
| Q36490547 | Phosphoinositide interacting regulator of TRP (Pirt) enhances TRPM8 channel activity in vitro via increasing channel conductance |
| Q38222958 | Phosphoinositide regulation of TRP channels |
| Q38371076 | Phosphoinositide regulation of TRPV1 revisited |
| Q37289145 | Phosphoinositide regulation of non-canonical transient receptor potential channels |
| Q36945667 | Phosphoinositide signaling in somatosensory neurons |
| Q35078016 | Phosphoinositide signaling: new tools and insights. |
| Q37234752 | Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1. |
| Q34403645 | Phosphoinositides as key regulators of synaptic function |
| Q35192402 | Phosphoinositides regulate ion channels. |
| Q27012953 | Phosphoinositides: tiny lipids with giant impact on cell regulation |
| Q45912640 | Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain. |
| Q37182896 | Phospholipase C mediated modulation of TRPV1 channels. |
| Q37018810 | Phospholipase C{beta}3 in mouse and human dorsal root ganglia and spinal cord is a possible target for treatment of neuropathic pain |
| Q44115082 | Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization. |
| Q42089811 | Photoswitchable fatty acids enable optical control of TRPV1. |
| Q24653664 | Physiology and pharmacology of the vanilloid receptor |
| Q28509103 | Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1 |
| Q53445626 | Potential Mechanisms Underlying Centralized Pain and Emerging Therapeutic Interventions. |
| Q35690268 | Potentiation of TRPV3 channel function by unsaturated fatty acids |
| Q79960832 | Potentiation of glutamatergic synaptic transmission by protein kinase C-mediated sensitization of TRPV1 at the first sensory synapse |
| Q80093184 | Potentiation of transient receptor potential V1 functions by the activation of metabotropic 5-HT receptors in rat primary sensory neurons |
| Q38185068 | Pro-neurotrophins, sortilin, and nociception |
| Q37294604 | Progranulin contributes to endogenous mechanisms of pain defense after nerve injury in mice |
| Q28568121 | Prolactin modulates TRPV1 in female rat trigeminal sensory neurons |
| Q37368601 | Promiscuous activation of transient receptor potential vanilloid 1 (TRPV1) channels by negatively charged intracellular lipids: the key role of endogenous phosphoinositides in maintaining channel activity |
| Q36946686 | Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums. |
| Q44115026 | Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia. |
| Q36635888 | Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling. |
| Q40263672 | Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice |
| Q43677197 | Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. |
| Q40204850 | Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice |
| Q38154631 | Protease-activated receptor 2 signalling pathways: a role in pain processing |
| Q36211460 | Protease-activated receptors: regulation of neuronal function |
| Q35037133 | Protein kinase C epsilon contributes to basal and sensitizing responses of TRPV1 to capsaicin in rat dorsal root ganglion neurons |
| Q36840305 | Protein kinase C in pain: involvement of multiple isoforms |
| Q36350876 | Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). |
| Q38287480 | Protein kinase C(alpha) is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways |
| Q44885100 | Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain. |
| Q47889530 | Quenching fire with fat: phosphatidylinositides as putative regulators of pain |
| Q30519202 | Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons |
| Q46361361 | Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain. |
| Q37251620 | Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons |
| Q42468468 | Receptor tyrosine kinases mediate epithelial Na(+) channel inhibition by epidermal growth factor |
| Q36132058 | Receptor-operated cation channels formed by TRPC4 and TRPC5. |
| Q89509852 | Reciprocal Regulatory Interaction between TRPV1 and Kinin B1 Receptor in a Rat Neuropathic Pain Model |
| Q36577096 | Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8. |
| Q91905163 | Recovery from tachyphylaxis of TRPV1 coincides with recycling to the surface membrane |
| Q37226097 | Regulation of Ca2+ entry by inositol lipids in mammalian cells by multiple mechanisms |
| Q39448481 | Regulation of Piezo Channels by Cellular Signaling Pathways. |
| Q36619448 | Regulation of TRP channels by PIP(2). |
| Q33676168 | Regulation of TRPV1 ion channel by phosphoinositide (4,5)-bisphosphate: the role of membrane asymmetry |
| Q36295878 | Regulation of gating and rundown of HCN hyperpolarization-activated channels by exogenous and endogenous PIP2 |
| Q36986504 | Regulation of ion transport proteins by membrane phosphoinositides |
| Q85207484 | Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids |
| Q36443034 | Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides |
| Q33920858 | Regulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphate |
| Q35103910 | Regulation of the temperature-dependent activation of transient receptor potential vanilloid 1 (TRPV1) by phospholipids in planar lipid bilayers |
| Q35795763 | Regulation of the transient receptor potential channel TRPM3 by phosphoinositides |
| Q36811208 | Regulation of transient receptor potential (TRP) channels by phosphoinositides |
| Q26822505 | Regulation of transient receptor potential channels by the phospholipase C pathway |
| Q40146865 | Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids |
| Q41333012 | Regulatory effect of nerve growth factor on release of substance P in cultured dorsal root ganglion neurons of rat. |
| Q35452699 | Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1. |
| Q37362056 | Resolvins: Endogenously-Generated Potent Painkilling Substances and their Therapeutic Perspectives |
| Q35035202 | Role of TRP channels in the cardiovascular system |
| Q37246141 | Role of TRPV1 in inflammation-induced airway hypersensitivity |
| Q46462944 | Role of chloride channels in bradykinin-induced guinea pig airway vagal C-fibre activation |
| Q26784212 | Role of oxidative stress & transient receptor potential in chronic obstructive pulmonary disease |
| Q38789318 | Role of reactive oxygen species and TRP channels in the cough reflex |
| Q37388690 | Roles of transient receptor potential channels in pain |
| Q38088356 | Screening TRPV1 antagonists for the treatment of pain: lessons learned over a decade |
| Q21090192 | Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber) |
| Q33503225 | Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia |
| Q33904526 | Sensing hot and cold with TRP channels |
| Q37877826 | Sensing pulmonary oxidative stress by lung vagal afferents |
| Q36366469 | Sensing with TRP channels |
| Q35790540 | Sensitisation of gastrointestinal tract afferents |
| Q24810227 | Sensitization and translocation of TRPV1 by insulin and IGF-I. |
| Q28757606 | Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain |
| Q24806526 | Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins |
| Q26827704 | Sensory TRP channel interactions with endogenous lipids and their biological outcomes |
| Q38368325 | Sensory TRP channels: the key transducers of nociception and pain. |
| Q27693846 | Sensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures |
| Q38201386 | Sensory nerves in lung and airways |
| Q41686577 | Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus |
| Q34928837 | Sensory neurone responses to mucosal noxae in the upper gut: relevance to mucosal integrity and gastrointestinal pain |
| Q38021306 | Sensory neurons, ion channels, inflammation and the onset of neuropathic pain. |
| Q37407633 | Serotonergic neuromodulation of peripheral nociceptors |
| Q36853422 | Serotonin Receptor 2B Mediates Mechanical Hyperalgesia by Regulating Transient Receptor Potential Vanilloid 1 |
| Q35243998 | Serotonin increases the functional activity of capsaicin-sensitive rat trigeminal nociceptors via peripheral serotonin receptors. |
| Q39365330 | Sex-dependent expression of TRPV1 in bladder arterioles |
| Q87462009 | Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors |
| Q44483450 | Signalling pathways involved in the sensitisation of mouse nociceptive neurones by nerve growth factor |
| Q44218020 | Single-channel properties of native and cloned rat vanilloid receptors |
| Q36506375 | Small molecule vanilloid TRPV1 receptor antagonists approaching drug status: can they live up to the expectations? |
| Q24307989 | Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling |
| Q46707156 | Sperm Release From the Oviductal Epithelium Depends on Ca(2+) Influx Upon Activation of CB1 and TRPV1 by Anandamide |
| Q89469272 | Structural insights into the gating mechanisms of TRPV channels |
| Q36170840 | Structure and function of TRPV1. |
| Q64963763 | Structure and gating mechanism of the transient receptor potential channel TRPV3. |
| Q36124582 | Structure-function analysis of TRPV channels |
| Q38695283 | Studying complex system: calcium oscillations as attractor of cell differentiation |
| Q34796577 | Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit |
| Q52684421 | Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception. |
| Q41887515 | Synthesis and biological activity of phospholipase C-resistant analogues of phosphatidylinositol 4,5-bisphosphate. |
| Q46703338 | Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats |
| Q30405316 | TNF-α/TNFR1 signaling is required for the development and function of primary nociceptors |
| Q27348801 | TNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18-1/syntaxin1/SNAP-25 mediated fusion |
| Q89575217 | TRP Channel Involvement in Salivary Glands-Some Good, Some Bad |
| Q37948046 | TRP Channels as Sensors and Signal Integrators of Redox Status Changes |
| Q37941467 | TRP channel antagonists as potential antitussives |
| Q46417237 | TRP channel structural biology: new roles for an old fold |
| Q35915824 | TRP channels and Ca2+ signaling |
| Q27021608 | TRP channels and analgesia |
| Q36600727 | TRP channels and lipids: from Drosophila to mammalian physiology. |
| Q46357812 | TRP channels and pain |
| Q29615917 | TRP channels as cellular sensors |
| Q35135471 | TRP channels in Drosophila photoreceptors: the lipid connection |
| Q24618774 | TRP channels in neurogastroenterology: opportunities for therapeutic intervention |
| Q38984941 | TRP channels: potential drug target for neuropathic pain |
| Q92652817 | TRP ion channels: Proteins with conformational flexibility |
| Q28508162 | TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents |
| Q30437078 | TRPC Channels Mediate a Muscarinic Receptor-Induced Afterdepolarization in Cerebral Cortex |
| Q46458006 | TRPC channels and diacylglycerol dependent calcium signaling in rat sensory neurons |
| Q36160932 | TRPV channels as thermosensory receptors in epithelial cells |
| Q36487773 | TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. |
| Q37148698 | TRPV1 Antagonists and Chronic Pain: Beyond Thermal Perception |
| Q40549949 | TRPV1 acts as proton channel to induce acidification in nociceptive neurons |
| Q27015036 | TRPV1 and SP: key elements for sepsis outcome? |
| Q39212353 | TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization. |
| Q34566005 | TRPV1 antagonist attenuates postoperative hypersensitivity by central and peripheral mechanisms |
| Q36966751 | TRPV1 antagonists as potential antitussive agents |
| Q35574193 | TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs |
| Q36536519 | TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cells |
| Q36640761 | TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids |
| Q45127969 | TRPV1 function in mouse colon sensory neurons is enhanced by metabotropic 5-hydroxytryptamine receptor activation. |
| Q34974218 | TRPV1 in Salivary Gland Epithelial Cells Is Not Involved in Salivary Secretion via Transcellular Pathway |
| Q28834315 | TRPV1 ligands with hyperthermic, hypothermic and no temperature effects in rats |
| Q46970956 | TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1. |
| Q28263455 | TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists |
| Q40415348 | TRPV1 regulators mediate gentamicin penetration of cultured kidney cells. |
| Q37761969 | TRPV1 splice variants: structure and function |
| Q26738621 | TRPV1: A Target for Rational Drug Design |
| Q36997807 | TRPV1: Turning up the heat on intestinal tumorigenesis |
| Q38022033 | TRPV1: a stress response protein in the central nervous system. |
| Q24649067 | TRPV1: a target for next generation analgesics |
| Q24650367 | TRPV1: on the road to pain relief |
| Q51833369 | TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes |
| Q30483343 | TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells |
| Q38587736 | TRPs and pain |
| Q28742340 | Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity |
| Q37827172 | Targeted treatment of pruritus: a look into the future |
| Q34555756 | Targeting TRP channels for novel migraine therapeutics |
| Q36333374 | Targeting TRPV1 for Body Weight Control using TRPV1(-/-) Mice and Electroacupuncture |
| Q37894474 | Targeting peripheral afferent nerve terminals for cough and dyspnea |
| Q35577723 | The Burden of Pain on the Shoulders of Aging |
| Q34410954 | The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate |
| Q36863976 | The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1 |
| Q37149019 | The Molecular and Pharmacological Mechanisms of HIV-Related Neuropathic Pain |
| Q28206986 | The TRP channels, a remarkably functional family |
| Q34397161 | The TRP superfamily of cation channels |
| Q28213790 | The TRPM7 channel is inactivated by PIP(2) hydrolysis |
| Q30493890 | The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels |
| Q36628759 | The bladder epithelium and overactive bladder: what we know |
| Q34457658 | The complex and intriguing lives of PIP2 with ion channels and transporters |
| Q36944706 | The complications of promiscuity: endocannabinoid action and metabolism |
| Q46551406 | The contribution of TRPM8 channels to cold sensing in mammalian neurones |
| Q34586922 | The diversity in the vanilloid (TRPV) receptor family of ion channels |
| Q36726641 | The emerging role of TRP channels in mechanisms of temperature and pain sensation |
| Q42661952 | The endoplasmic reticulum of dorsal root ganglion neurons contains functional TRPV1 channels |
| Q35669849 | The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain |
| Q27014891 | The functional and anatomical dissection of somatosensory subpopulations using mouse genetics |
| Q37974692 | The functions of TRPA1 and TRPV1: moving away from sensory nerves |
| Q37207516 | The glutamatergic nature of TRPV1-expressing neurons in the spinal dorsal horn |
| Q44390700 | The inflammatory mediators serotonin, prostaglandin E2 and bradykinin evoke calcium influx in rat sensory neurons. |
| Q28247676 | The neurobiology of itch |
| Q41984053 | The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions. |
| Q42371395 | The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of DOMS associated impairment |
| Q38033056 | The role of chemosensitive afferent nerves and TRP ion channels in the pathomechanism of headaches. |
| Q24802890 | The role of mast cells in the pathogenesis of pain in chronic pancreatitis |
| Q42452211 | The role of the TRPV1 endogenous agonist N-Oleoyldopamine in modulation of nociceptive signaling at the spinal cord level |
| Q43697676 | The role of transient receptor potential ankyrin 1 (TRPA1) channel in activation of single unit mechanosensitive bladder afferent activities in the rat. |
| Q40516374 | The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel |
| Q37907351 | The thermo-TRP ion channel family: properties and therapeutic implications |
| Q38166282 | The transition from acute to chronic pain: understanding how different biological systems interact |
| Q28512507 | The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons |
| Q28295455 | The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation |
| Q36803753 | The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept |
| Q42505527 | The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. |
| Q41901432 | Thermal nociception and TRPV1 function are attenuated in mice lacking the nucleotide receptor P2Y2. |
| Q35167938 | ThermoTRP channels and beyond: mechanisms of temperature sensation |
| Q36216355 | ThermoTRP channels and cold sensing: what are they really up to? |
| Q37104144 | ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1 |
| Q36067431 | Thermosensitive transient receptor potential (TRP) channel agonists and their role in mechanical, thermal and nociceptive sensations as assessed using animal models |
| Q80226392 | Three distinct muscarinic signalling pathways for cationic channel activation in mouse gut smooth muscle cells |
| Q38774298 | Tissue kallikrein stimulates Ca(2+) reabsorption via PKC-dependent plasma membrane accumulation of TRPV5. |
| Q34120813 | Towards a mechanism-based approach to pain management in osteoarthritis |
| Q36462719 | Transduction mechanisms in airway sensory nerves |
| Q33562184 | Transient receptor potential (TRP) channels in the airway: role in airway disease |
| Q33562143 | Transient receptor potential (TRP) channels: a clinical perspective |
| Q37986932 | Transient receptor potential A1 receptor-mediated neural cross-talk and afferent sensitization induced by oxidative stress: implication for the pathogenesis of interstitial cystitis/bladder pain syndrome |
| Q51796609 | Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-directed internalization. |
| Q38056773 | Transient receptor potential channels in bladder function |
| Q36246847 | Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin |
| Q38166804 | Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics. |
| Q64901211 | Transient receptor potential ion-channel subfamily V member 4: a potential target for cancer treatment. |
| Q52721399 | Transient receptor potential polymorphism and haplotype associate with crisis pain in sickle cell disease. |
| Q59282561 | Transient receptor potential vanilloid 1 mediates nerve growth factor-induced bladder hyperactivity and noxious input |
| Q37180517 | Transient receptor potential vanilloid channels in hypertension, inflammation, and end organ damage: an imminent target of therapy for cardiovascular disease? |
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