6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a randomised, double-blind, placebo-controlled trial

scientific article

6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a randomised, double-blind, placebo-controlled trial is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0140-6736(11)60204-3
P698PubMed publication ID21492926

P50authorZegabriel TedlaQ57890252
Peter H. KilmarxQ40133323
P2093author name stringNong Shang
Kenneth G Castro
Elizabeth A Talbot
Lorna Bozeman
Charles D Wells
Taraz Samandari
Barudi Mosimaneotsile
Margarett K Davis
Howard J Moffat
Samba Nyirenda
Thabisa Sibanda
Themba L Moeti
Tefera B Agizew
Oaitse I Motsamai
P2860cites workEffect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: a cohort studyQ46778392
Effect of isoniazid prophylaxis on incidence of active tuberculosis and progression of HIV infectionQ72225808
Preventing latent tuberculosis among HIV-infected patients: efficacious and effective, yet inefficient?Q79402182
Treatment of latent tuberculosis infection in HIV infected personsQ24241052
Impact of antiretroviral therapy on the incidence of tuberculosis: the Brazilian experience, 1995-2001Q28469286
Long-term effect of preventive therapy for tuberculosis in a cohort of HIV-infected Zambian adultsQ32054823
Effect of preventive treatment for tuberculosis in adults infected with HIV: systematic review of randomised placebo controlled trialsQ33832950
Molecular and conventional epidemiology of Mycobacterium tuberculosis in Botswana: a population-based prospective study of 301 pulmonary tuberculosis patientsQ33971595
Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural CambodiaQ34064629
The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, BrazilQ34717877
Isoniazid preventive therapy, HAART and tuberculosis risk in HIV-infected adults in South Africa: a prospective cohortQ34717889
IL-10-producing T cells suppress immune responses in anergic tuberculosis patientsQ35159232
Towards universal access to HIV prevention, treatment, care, and support: the role of tuberculosis/HIV collaborationQ36548072
Association of isoniazid preventive therapy with lower early mortality in individuals on antiretroviral therapy in a workplace programmeQ37047696
Short-term and long-term risk of tuberculosis associated with CD4 cell recovery during antiretroviral therapy in South AfricaQ37240761
High rates of clustering of strains causing tuberculosis in Harare, Zimbabwe: a molecular epidemiological studyQ37576902
Prevalence, incidence and mortality associated with tuberculosis in HIV-infected patients initiating antiretroviral therapy in rural UgandaQ38878250
Cytokine responses and progression to active tuberculosis in HIV-1-infected Ugandans: a prospective studyQ38881717
Duration of efficacy of treatment of latent tuberculosis infection in HIV-infected adultsQ38884867
A trial of three regimens to prevent tuberculosis in Ugandan adults infected with the human immunodeficiency virus. Uganda-Case Western Reserve University Research CollaborationQ38887663
Recent transmission of tuberculosis in a cohort of HIV-1-infected female sex workers in Nairobi, KenyaQ39023628
The importance of recent infection with Mycobacterium tuberculosis in an area with high HIV prevalence: a long-term molecular epidemiological study in Northern MalawiQ39025474
Burden of tuberculosis in an antiretroviral treatment programme in sub-Saharan Africa: impact on treatment outcomes and implications for tuberculosis controlQ39163402
Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosisQ39713565
Isoniazid-associated hepatitis and antiretroviral drugs during tuberculosis prophylaxis in hiv-infected adults in BotswanaQ40797865
Scaling up ART treatment capacity: lessons learned from South Africa, Zimbabwe, and BotswanaQ40798969
Value of chest radiography in a tuberculosis prevention programme for HIV-infected people, BotswanaQ40800733
Rifampin and pyrazinamide vs isoniazid for prevention of tuberculosis in HIV-infected persons: an international randomized trial. Terry Beirn Community Programs for Clinical Research on AIDS, the Adult AIDS Clinical Trials Group, the Pan American HeQ42622399
Randomized trial of three regimens to prevent tuberculosis in HIV-infected patients with anergyQ44479756
Reduced risk of tuberculosis among Brazilian patients with advanced human immunodeficiency virus infection treated with highly active antiretroviral therapyQ45734056
A controlled trial of isoniazid in persons with anergy and human immunodeficiency virus infection who are at high risk for tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS.Q45761546
Twice weekly tuberculosis preventive therapy in HIV infection in ZambiaQ46730612
P433issue9777
P407language of work or nameEnglishQ1860
P921main subjectBotswanaQ963
tuberculosisQ12204
HIVQ15787
placeboQ269829
isoniazidQ423169
P304page(s)1588-1598
P577publication date2011-04-12
P1433published inThe LancetQ939416
P1476title6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a randomised, double-blind, placebo-controlled trial
P478volume377

Reverse relations

cites work (P2860)
Q28547313A Clinical Algorithm to Identify HIV Patients at High Risk for Incident Active Tuberculosis: A Prospective 5-Year Cohort Study
Q35766814A Description of Mortality Associated with IPT plus ART Compared to ART Alone among HIV-Infected Individuals in Addis Ababa, Ethiopia: A Cohort Study
Q34533997A recent HIV diagnosis is associated with non-completion of Isoniazid Preventive Therapy in an HIV-infected cohort in Cape Town
Q37702101Ability of preventive therapy to cure latent Mycobacterium tuberculosis infection in HIV-infected individuals in high-burden settings
Q33759993Added value of QuantiFERON TB-gold in-tube for detecting latent tuberculosis infection among persons living with HIV/AIDS.
Q54222775Addressing knowledge gaps and prevention for tuberculosis-infected Indian adults: a vital part of elimination.
Q40063284Adherence, tolerability, and outcome after 36 months of isoniazid-preventive therapy in 2 rural clinics of Swaziland: A prospective observational feasibility study
Q36106589Antiretroviral Treatment Scale-Up and Tuberculosis Mortality in High TB/HIV Burden Countries: An Econometric Analysis
Q34387168Antiretroviral therapy for prevention of tuberculosis in adults with HIV: a systematic review and meta-analysis
Q42233906Aspiring to zero tuberculosis deaths among southern Africa's miners: is there a way forward?
Q38619860Benefits of combined preventive therapy with co-trimoxazole and isoniazid in adults living with HIV: time to consider a fixed-dose, single tablet coformulation
Q38805328Benefits of continuous isoniazid preventive therapy may outweigh resistance risks in a declining tuberculosis/HIV coepidemic
Q92572142Building a tuberculosis-free world: The Lancet Commission on tuberculosis
Q47094082CD4 count and tuberculosis risk in HIV-positive adults not on ART: a systematic review and meta-analysis.
Q44032418Cancer in Botswana: resources and opportunities
Q37322344Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-[18F]fluoro-D-glucose positron emission and computed tomography
Q33596103Clinical outcomes among persons with pulmonary tuberculosis caused by Mycobacterium tuberculosis isolates with phenotypic heterogeneity in results of drug-susceptibility tests
Q37021617Community-wide isoniazid preventive therapy drives drug-resistant tuberculosis: a model-based analysis
Q35800557Comparison of screening strategies to improve the diagnosis of latent tuberculosis infection in the HIV-positive population: a cohort study
Q33768889Comparison of trends in tuberculosis incidence among adults living with HIV and adults without HIV--Kenya, 1998-2012
Q54916195Completion of isoniazid preventive therapy among human immunodeficiency virus positive adults in urban Malawi.
Q41284385Complicated silicotuberculosis in a South African gold miner: A case report
Q38686803Continuous isoniazid for the treatment of latent tuberculosis infection in people living with HIV.
Q64098100Controlling latent TB tuberculosis infection in high-burden countries: A neglected strategy to end TB
Q28087385Controlling the seedbeds of tuberculosis: diagnosis and treatment of tuberculosis infection
Q35577840Cost Effectiveness of Preventive Treatment for Tuberculosis in Special High-Risk Populations
Q34672436Cost-effectiveness of Quantiferon®-TB Gold-in-Tube versus tuberculin skin testing for contact screening and treatment of latent tuberculosis infection in Brazil
Q37192288Cost-effectiveness of isoniazid preventive therapy for HIV-infected pregnant women in India
Q36950190Cost-effectiveness of the Three I's for HIV/TB and ART to prevent TB among people living with HIV.
Q33746657Cost-effectiveness of tuberculosis screening and isoniazid treatment in the TB/HIV in Rio (THRio) Study
Q38066198Current management options for latent tuberculosis: a review
Q28069032Current trends and intricacies in the management of HIV-associated pulmonary tuberculosis
Q27015848Data needs for evidence-based decisions: a tuberculosis modeler's 'wish list'
Q35567798Debunking the myths perpetuating low implementation of isoniazid preventive therapy amongst human immunodeficiency virus-infected persons
Q26991633Diagnosis & treatment of tuberculosis in HIV co-infected patients
Q37960565Diagnosis and management of TB in children: an update
Q27021614Diagnosis and treatment of latent infection with Mycobacterium tuberculosis
Q34290177Diagnosis and treatment of latent tuberculosis infection: an update
Q39037330Does antiretroviral therapy reduce HIV-associated tuberculosis incidence to background rates? A national observational cohort study from England, Wales, and Northern Ireland
Q85024214Duration of isoniazid preventive therapy in HIV-infected patients
Q95396469Duration of isoniazid preventive therapy in HIV-infected patients
Q37507184Effect of improved tuberculosis screening and isoniazid preventive therapy on incidence of tuberculosis and death in patients with HIV in clinics in Rio de Janeiro, Brazil: a stepped wedge, cluster-randomised trial
Q35818084Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study.
Q47615033Effect of isoniazid preventive therapy on risk of death in west African, HIV-infected adults with high CD4 cell counts: long-term follow-up of the Temprano ANRS 12136 trial
Q35744636Effect of isoniazid preventive therapy on tuberculosis or death in persons with HIV: a retrospective cohort study.
Q30240445Effect of secondary preventive therapy on recurrence of tuberculosis in HIV-infected individuals: a systematic review
Q48171817Efficacy of Treatment for Latent Tuberculosis in Patients Undergoing Treatment with a Tumor Necrosis Factor Antagonist
Q34515554Efficacy of a six-month versus a 36-month regimen for prevention of tuberculosis in HIV-infected persons in India: a randomized clinical trial
Q37061089Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial
Q41009954Fluoroquinolone Therapy for the Prevention of Multidrug-Resistant Tuberculosis in Contacts. A Cost-Effectiveness Analysis
Q30385352Getting to 90-90-90 in paediatric HIV: What is needed?
Q89695446Guidelines for the Treatment of Latent Tuberculosis Infection: Recommendations from the National Tuberculosis Controllers Association and CDC, 2020
Q26824501HIV and tuberculosis--science and implementation to turn the tide and reduce deaths
Q39002151HIV viral load as an independent risk factor for tuberculosis in South Africa: collaborative analysis of cohort studies
Q64243730Health system barriers to implementation of TB preventive strategies in South African primary care facilities
Q27022370Hepatotoxicity from antituberculous therapy in the elderly: a systematic review
Q26824057How can mathematical models advance tuberculosis control in high HIV prevalence settings?
Q37103666Human immunodeficiency virus-associated tuberculosis: update on prevention and treatment
Q40600140IFN-γ Release Assay Result Is Associated with Disease Site and Death in Active Tuberculosis
Q34639121Impact of isoniazid preventive therapy for HIV-infected adults in Rio de Janeiro, Brazil: an epidemiological model
Q33886920Impact of isoniazid preventive therapy on the evaluation of long-term effectiveness of infant MVA85A vaccination.
Q37461125Implementation and Operational Research: Cost-Effectiveness of Antiretroviral Therapy and Isoniazid Prophylaxis to Reduce Tuberculosis and Death in People Living With HIV in Botswana
Q38957843Implementation of isoniazid preventive therapy in an HIV clinic in Cambodia: high rates of discontinuation when combined with antiretroviral therapy
Q38841837Implementing isoniazid preventive therapy in a tuberculosis treatment-experienced cohort on ART.
Q35357639Improving the prevention, diagnosis and treatment of TB among people living with HIV: the role of operational research
Q90683207Incidence and predictors of tuberculosis occurrence among adults on antiretroviral therapy at Debre Markos referral hospital, Northwest Ethiopia: retrospective follow-up study
Q92598911Incidence of tuberculosis among HIV infected individuals on long term antiretroviral therapy in private healthcare sector in Pune, Western India
Q40794905Increase in anti-tuberculosis drug resistance in Botswana: results from the fourth National Drug Resistance Survey
Q92858776Infant TB Infection Prevention Study (iTIPS): a randomised trial protocol evaluating isoniazid to prevent M. tuberculosis infection in HIV-exposed uninfected children
Q90669515Intensified household contact tracing, prevention and treatment support versus enhanced standard of care for contacts of tuberculosis cases in South Africa: study protocol for a household cluster-randomised trial
Q36599355Interferon release does not add discriminatory value to smear-negative HIV-tuberculosis algorithms.
Q36637982Interferon-Gamma Release Assays versus Tuberculin Skin Testing for the Diagnosis of Latent Tuberculosis Infection: An Overview of the Evidence
Q38168914Interferon-gamma release assays for tuberculosis: current and future applications
Q40522525Is systematic screening and treatment for latent tuberculosis infection in HIV patients useful in a low endemic setting?
Q46171041Isoniazid Preventive Therapy for People with HIV who are Heavy Alcohol Drinkers in High TB/HIV Burden Countries: a Risk-Benefit Analysis
Q90438291Isoniazid Preventive Therapy in HIV-Infected Pregnant and Postpartum Women
Q26778385Isoniazid Prophylactic Therapy for the Prevention of Tuberculosis in HIV Infected Adults: A Systematic Review and Meta-Analysis of Randomized Trials
Q34519039Isoniazid plus antiretroviral therapy to prevent tuberculosis: a randomised double-blind, placebo-controlled trial
Q57827499Isoniazid preventive therapy in HIV infection
Q42245812Life expectancy difference and life expectancy ratio: two measures of treatment effects in randomised trials with non-proportional hazards
Q35197248Long-term protection from isoniazid preventive therapy for tuberculosis in HIV-infected patients in a medium-burden tuberculosis setting: the TB/HIV in Rio (THRio) study
Q34467936Longer hospital stay is associated with higher rates of tuberculosis-related morbidity and mortality within 12 months after discharge in a referral hospital in Sub-Saharan Africa
Q38107500Management of tuberculosis and latent tuberculosis infection in human immunodeficiency virus-infected persons
Q38259519Meningitis in HIV-positive patients in sub-Saharan Africa: a review
Q36171368Molecular epidemiology of HIV-associated tuberculosis in Dar es Salaam, Tanzania: strain predominance, clustering, and polyclonal disease
Q58592157Moving Toward Tuberculosis Elimination: Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection
Q37061276Mycobacterial Etiology of Pulmonary Tuberculosis and Association with HIV Infection and Multidrug Resistance in Northern Nigeria
Q36125227New regimens to prevent tuberculosis in adults with HIV infection
Q35947091Pathogen-specific T cell depletion and reactivation of opportunistic pathogens in HIV infection
Q40696371Poor agreement between diagnostic tests for latent tuberculosis infection among HIV-infected persons in Hong Kong
Q34999621Predicting the long-term impact of antiretroviral therapy scale-up on population incidence of tuberculosis
Q27000984Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis
Q34648833Predictors of tuberculosis and human immunodeficiency virus co-infection: a case-control study
Q36711601Pregnancy outcomes in HIV-infected women receiving long-term isoniazid prophylaxis for tuberculosis and antiretroviral therapy
Q34589601Prevalent and incident tuberculosis are independent risk factors for mortality among patients accessing antiretroviral therapy in South Africa
Q54215180Preventive treatment for tuberculosis in people with HIV.
Q37626250Prognostic significance of the interval between the initiation of antiretroviral therapy and the initiation of anti-tuberculosis treatment in HIV/tuberculosis-coinfected patients: results from the TREAT Asia HIV Observational Database
Q57460874Projected population-wide impact of antiretroviral therapy-linked isoniazid preventive therapy in a high-burden setting
Q92365471Provider barriers to the uptake of isoniazid preventive therapy among people living with HIV in Ethiopia
Q37520181Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy
Q38797602Reactivation tuberculosis: role of surveillance
Q37940571Redefining latent tuberculosis
Q37285167Reducing deaths from tuberculosis in antiretroviral treatment programmes in sub-Saharan Africa
Q47145955Rheumatic heart disease: infectious disease origin, chronic care approach.
Q24201325Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB
Q41657767Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB.
Q36154640Risk factors associated with indeterminate gamma interferon responses in the assessment of latent tuberculosis infection in a high-incidence environment
Q33889133Risk factors for non-adherence and loss to follow-up in a three-year clinical trial in Botswana
Q33768706Risk factors for treatment default in close contacts with latent tuberculous infection
Q35566421Risk of Active Tuberculosis in HIV-Infected Patients in Taiwan with Free Access to HIV Care and a Positive T-Spot.TB Test
Q38819485Scale-up of collaborative TB/HIV activities in Guyana
Q38011369Scaling up interventions to achieve global tuberculosis control: progress and new developments
Q61815841Scaling up isoniazid preventive therapy in Zimbabwe: has operational research influenced policy and practice?
Q38783382Screening and treatment of latent tuberculosis infection among HIV-infected patients in resource-rich settings.
Q42923385Short-course untargeted isoniazid preventive therapy in South Africa: time to rethink policy?
Q35547966Statistical inference methods for two crossing survival curves: a comparison of methods
Q28478920Strategies for treating latent multiple-drug resistant tuberculosis: a decision analysis
Q34499835Systematic review of TST responses in people living with HIV in under-resourced settings: implications for isoniazid preventive therapy
Q33805502Systematic review of facility-based sexual and reproductive health services for female sex workers in Africa
Q59359915TB preventive therapy for people living with HIV: key considerations for scale-up in resource-limited settings
Q46706694Taking the long view on the CREATE studies' findings
Q37284765Temporal association between incident tuberculosis and poor virological outcomes in a South African antiretroviral treatment service
Q53727381The ENRICH Study to evaluate the effectiveness of a combination intervention package to improve isoniazid preventive therapy initiation, adherence and completion among people living with HIV in Ethiopia: rationale and design of a mixed methods clust
Q38863238The HIV basic care package: where is it available and who receives it? Findings from a mixed methods evaluation in Kenya and Uganda
Q91790814The Mtb-HIV syndemic interaction: why treating M. tuberculosis infection may be crucial for HIV-1 eradication
Q42279763The Twin Epidemics of Tuberculosis and HIV.
Q40095857The clinical utility of the urine-based lateral flow lipoarabinomannan assay in HIV-infected adults in Myanmar: an observational study
Q28483035The cost-effectiveness of tuberculosis preventive therapy for HIV-infected individuals in southern India: a trial-based analysis
Q35382545The effect of isoniazid preventive therapy on incidence of tuberculosis among HIV-infected clients under pre-ART care, Jimma, Ethiopia: a retrospective cohort study
Q47159987The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana
Q51833634The molecular epidemiology of tuberculosis in settings with a high HIV prevalence: implications for control.
Q34251459The pharmacokinetics of nevirapine when given with isoniazid in South African HIV-infected individuals
Q34802722The proportions of people living with HIV in low and middle-income countries who test tuberculin skin test positive using either a 5 mm or a 10 mm cut-off: a systematic review
Q30385976The rise and fall of tuberculosis in Malawi: associations with HIV infection and antiretroviral therapy.
Q64079571The shift in tuberculosis timing among people living with HIV in the course of antiretroviral therapy scale-up in Malawi
Q36720436The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study
Q38729690The transmission of Mycobacterium tuberculosis in high burden settings
Q37525288Timely HIV diagnosis and HIV/TB comanagement among California patients in 2008.
Q47955589To eliminate tuberculosis, we must universally encourage treatment of its latent form
Q62487117Tolerability of Isoniazid Preventive Therapy in an HIV-Infected Cohort of Paediatric and Adolescent Patients on Antiretroviral Therapy from a Resource-Limited Setting: A Retrospective Cohort Study
Q36137225Treatment of latent tuberculosis infection in HIV: shorter or longer?
Q55440266Tuberculin Skin Test Conversion among Individuals with Human Immunodeficiency Virus Infection on Antiretroviral Therapy in a Referral Teaching Hospital, Tehran, Iran.
Q57235679Tuberculosis
Q59200569Tuberculosis
Q35297467Tuberculosis control in South African gold mines: mathematical modeling of a trial of community-wide isoniazid preventive therapy
Q64357339Tuberculosis decline in populations affected by HIV: a retrospective study of 12 countries in the WHO African Region
Q45998638Tuberculosis in HIV-infected persons in British Columbia during the HAART era.
Q37461120Tuberculosis incidence after 36 months' isoniazid prophylaxis in HIV-infected adults in Botswana: a posttrial observational analysis
Q36078532Tuberculosis incidence rate and risk factors among HIV-infected adults with access to antiretroviral therapy
Q34222186Tuberculosis incidence rates during 8 years of follow-up of an antiretroviral treatment cohort in South Africa: comparison with rates in the community
Q35304473Tuberculosis prevention in South Africa
Q58580044Tuberculosis preventive treatment: the next chapter of tuberculosis elimination in India
Q51120505Tuberculosis screening and isoniazid preventive therapy implementation: a Brazilian experience.
Q26774267Tuberculosis: opportunities and challenges for the 90-90-90 targets in HIV-infected children
Q53669745Under-reporting of venous and arterial thrombotic events in randomized clinical trials: a meta-analysis.
Q36238015Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies
Q28073158Updates on the risk factors for latent tuberculosis reactivation and their managements
Q38376719Use of isoniazid preventive therapy for tuberculosis prophylaxis among people living with HIV/AIDS: a review of the literature
Q46361434Venous thromboembolism prophylaxis, shorter courses of isoniazid for tuberculosis, and the microbiome in asthma
Q28066845What can we offer to 3 million MDRTB household contacts in 2016?
Q36044825Wide Variations in Compliance with Tuberculosis Screening Guidelines and Tuberculosis Incidence between Antiretroviral Therapy Facilities - Côte d'Ivoire
Q33790711Year in review 2011: respiratory infections, tuberculosis, pleural diseases, bronchoscopic intervention and imaging
Q26753069Year in review 2015: Lung cancer, pleural diseases, respiratory infections, bronchiectasis and tuberculosis, bronchoscopic intervention and imaging
Q28817658[Au]/[Ag]-catalysed expedient synthesis of branched heneicosafuranosyl arabinogalactan motif of Mycobacterium tuberculosis cell wall
Q84590878[Clinical presentation of tuberculosis in routine practice]

Search more.