review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1111/J.1600-065X.1993.TB00645.X |
P698 | PubMed publication ID | 8282319 |
P50 | author | Polly Matzinger | Q3395388 |
P2860 | cites work | Approaching the asymptote? Evolution and revolution in immunology | Q28274344 |
Sequence analysis of peptides bound to MHC class II molecules | Q28303686 | ||
Mice lacking MHC class II molecules | Q28588991 | ||
In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 type | Q34321361 | ||
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. | Q34350288 | ||
Activation events during thymic selection | Q36231057 | ||
A fail-safe mechanism for maintaining self-tolerance | Q36231679 | ||
CD4 expression is differentially required for deletion of MLS-1a-reactive T cells. | Q36231917 | ||
Is self tolerance H-2 restricted? | Q72078236 | ||
A one-receptor view of T-cell behaviour | Q72639690 | ||
Evidence from in vitro studies that tolerance to self antigens is MHC-restricted | Q72813262 | ||
High determinant density may explain the phenomenon of alloreactivity | Q85697732 | ||
Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocytes | Q36269318 | ||
On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition? | Q36340069 | ||
The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens | Q36342063 | ||
Major histocompatibility complex-restricted self-recognition in responses to trinitrophenyl-ficoll. Adaptive differentiation and self-recognition by B cells | Q36347133 | ||
Role of the H-2 complex in the induction of T cell tolerance to self minor histocompatibility antigens | Q36348228 | ||
T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages | Q36353463 | ||
In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B. | Q36353659 | ||
Split tolerance induced by the intrathymic adoptive transfer of thymocyte stem cells | Q36355129 | ||
Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways | Q36356927 | ||
Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens | Q36357663 | ||
Thymus epithelium induces tissue-specific tolerance | Q36361553 | ||
MHC restriction, alloreactivity, and thymic education: a common link? | Q38219862 | ||
Selective induction of T-cell subsets by antibodies to the T-cell antigen receptor and to the subset-specific differentiation antigens CD8 and CD4. | Q39486438 | ||
Cross-linking of CD4 and CD8 with the T-cell receptor complex: quaternary complex formation and T-cell repertoire selection | Q39579771 | ||
A speculative view of the multicomponent nature of T cell antigen recognition | Q39589017 | ||
Patterns of virus-immune T-cell responsiveness. Comparison of (H-2(k) x H-2(b)) {arrow} H-2(b) Radiation Chimeras and negatively selected H-2(b) lymphocytes | Q39694872 | ||
Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens? | Q40643054 | ||
Influence of the major histocompatibility complex on lymphocyte interactions in antibody formation | Q40680962 | ||
T-cell inhibition of humoral responsiveness. II. Theory on the role of restrictive recognition in immune regulation | Q40690063 | ||
Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complex | Q40701083 | ||
Specificity of T-cell cones illustrates altered self hypothesis | Q41612846 | ||
Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule | Q41623815 | ||
Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells | Q41807593 | ||
Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny | Q42141543 | ||
Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cells | Q42767921 | ||
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin | Q42936502 | ||
Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage | Q43960795 | ||
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages | Q44151375 | ||
Does T-cell tolerance require a dedicated antigen-presenting cell? | Q46491587 | ||
Unresponsiveness to a foreign antigen can be caused by self-tolerance | Q46860879 | ||
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells. | Q52483263 | ||
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules | Q55042699 | ||
T cell tolerance by clonal elimination in the thymus | Q56922465 | ||
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction. | Q57275625 | ||
A critical role of λ5 protein in B cell development | Q57339983 | ||
Can B cells turn on virgin T cells? | Q59054988 | ||
Self tolerance is H–2-restricted | Q59058139 | ||
Minor but not major histocompatibility antigens of thymus epithelium tolerize precursors of cytolytic T cells | Q59063152 | ||
Identification of self peptides bound to purified HLA-B27 | Q59068162 | ||
Developmental regulation of T-cell receptor gene expression | Q59070328 | ||
Deletion of self-reactive T cells before entry into the thymus medulla | Q59071302 | ||
Participation of CD4 coreceptor molecules in T-cell repertoire selection | Q59096940 | ||
Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment | Q59097267 | ||
A beginner's guide to major histocompatibility complex function | Q64448665 | ||
Cim: an MHC class II-linked allelism affecting the antigenicity of a classical class I molecule for T lymphocytes | Q67998263 | ||
Three-receptor, clonal expansion model for selection of self-recognition in the thymus | Q72073261 | ||
P304 | page(s) | 81-117 | |
P577 | publication date | 1993-10-01 | |
P1433 | published in | Immunological Reviews | Q15724582 |
P1476 | title | Why positive selection? | |
P478 | volume | 135 |
Q41718895 | Aberrant expression of tissue-specific proteins in the thymus: a hypothesis for the development of central tolerance |
Q53969369 | CD6: expression during development, apoptosis and selection of human and mouse thymocytes. |
Q38817700 | Dissecting the two models of TCR structure-function relationships. |
Q34762312 | Efficient T cell repertoire selection in tetraparental chimeric mice independent of thymic epithelial MHC |
Q35930529 | Evidence for a single-niche model of positive selection |
Q35080684 | Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC. |
Q36380676 | How many thymocytes audition for selection? |
Q34122409 | Immunological principles of adverse drug reactions: the initiation and propagation of immune responses elicited by drug treatment |
Q48447599 | Immunology (1955-1975): the natural selection theory, the two signal hypothesis and positive repertoire selection |
Q35850625 | On 'reactivity' versus 'tolerance'. |
Q36415831 | On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells |
Q37101244 | Purified hematopoietic stem cell allografts reconstitute immunity superior to bone marrow |
Q35621984 | Regulatory T cells for tolerance therapy: revisiting the concept |
Q33930698 | Restricted and conserved T-cell repertoires involved in allorecognition of class II major histocompatibility complex. |
Q38952548 | Self-reactivity as the necessary cost of maintaining a diverse memory T-cell repertoire |
Q81420783 | The multigenic structure of the MHC locus contributes to positive selection efficiency: a role for MHC class II gene-specific restriction |
Q40895891 | The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules |
Q36376819 | The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex |
Q35077151 | Tritope model of restrictive recognition by the TCR. |
Q34792441 | Uncertainties - discrepancies in immunology |
Q34023421 | What is missing in immunology to understand immunity? |
Q73200543 | [Autoimmunity: a concept to be revisited?] |
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