Inhibitors of myelination: ECM changes, CSPGs and PTPs.

scientific article published on 4 November 2013

Inhibitors of myelination: ECM changes, CSPGs and PTPs. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EXPNEUROL.2013.10.017
P8608Fatcat IDrelease_u3232fv625gppjd6firkeevy4m
P932PMC publication ID4060786
P698PubMed publication ID24200549
P5875ResearchGate publication ID258347326

P50authorDanielle E HarlowQ83234688
P2093author name stringWendy B Macklin
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Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissueQ28566378
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Versican V2 is a major extracellular matrix component of the mature bovine brainQ42679048
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Expression of a catalytically inactive transmembrane protein tyrosine phosphatase epsilon (tm-PTP epsilon) delays optic nerve myelinationQ45076824
The extracellular matrix glycoprotein Tenascin-C is expressed by oligodendrocyte precursor cells and required for the regulation of maturation rate, survival and responsiveness to platelet-derived growth factorQ45153218
Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ.Q45893871
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NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors.Q46345563
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Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathwayQ47752933
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Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord.Q33944968
Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2Q33953332
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Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelinationQ34253257
Chondroitinase and growth factors enhance activation and oligodendrocyte differentiation of endogenous neural precursor cells after spinal cord injuryQ34282030
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Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's diseaseQ34351769
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation.Q34441121
Sulfation patterns of glycosaminoglycans encode molecular recognition and activityQ34552621
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Critical role for protein tyrosine phosphatase SHP-1 in controlling infection of central nervous system glia and demyelination by Theiler's murine encephalomyelitis virusQ35000580
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NG2: a component of the glial scar that inhibits axon growthQ36347824
Protein tyrosine phosphatase receptor type z negatively regulates oligodendrocyte differentiation and myelinationQ36380631
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Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3.Q36501925
Cortical remyelination: a new target for repair therapies in multiple sclerosis.Q36504051
Laminin forms an independent network in basement membranesQ36531408
Receptor protein tyrosine phosphatase from stem cells to mature glial cells of the central nervous systemQ36645426
The role of extracellular matrix in CNS regenerationQ36707967
Expression of decorin mRNA in the nervous system of rat.Q36767358
Pathogenic and regulatory roles for B cells in experimental autoimmune encephalomyelitisQ36803471
How does chondroitinase promote functional recovery in the damaged CNS?Q36850640
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A 'GAG' reflex prevents repair of the damaged CNS.Q37026388
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Extracellular matrix of the central nervous system: from neglect to challengeQ37241849
Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate.Q37378494
The relevance of animal models in multiple sclerosis researchQ37380834
Proteoglycans: from structural compounds to signaling moleculesQ37513784
Manipulating the glial scar: chondroitinase ABC as a therapy for spinal cord injuryQ37771571
Astrocyte phenotypes and their relationship to myelinationQ37865581
Chondroitin sulphate proteoglycans: extracellular matrix proteins that regulate immunity of the central nervous systemQ37888007
Extracellular matrix functions during neuronal migration and lamination in the mammalian central nervous systemQ37899107
Chondroitin sulfate: a key molecule in the brain matrix.Q37977716
Scar-mediated inhibition and CSPG receptors in the CNS.Q38029901
Myelination: do astrocytes play a role?Q38058202
Delayed treatment with chondroitinase ABC promotes sensorimotor recovery and plasticity after stroke in aged rats.Q38464672
Extracellular matrix molecules that influence neural developmentQ38613295
Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formationQ39115884
Chondroitinase ABC improves basic and skilled locomotion in spinal cord injured catsQ39225628
Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination.Q39266450
PTPBR7 binding proteins in myelinating neurons of the mouse brainQ39488829
The extracellular matrix of the central and peripheral nervous systems: structure and functionQ39652117
Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycansQ40030617
Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activationQ40033423
Tenascin-R and C in multiple sclerosis lesions: relevance to extracellular matrix remodellingQ48154136
Fibronectin aggregation in multiple sclerosis lesions impairs remyelinationQ48187024
Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cellsQ48205076
Prominent oligodendrocyte genesis along the border of spinal contusion lesions.Q48256973
Extensive extracellular matrix depositions in active multiple sclerosis lesionsQ48411670
The extracellular matrix in multiple sclerosis lesionsQ48463739
Identification of neurite outgrowth-promoting domains of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, and involvement of phosphatidylinositol 3-kinase and protein kinase C signaling pathways in neuritogenesisQ48486349
Inhibition of axon growth by oligodendrocyte precursor cellsQ48584765
Digitized image analysis reveals diffuse abnormalities in normal-appearing white matter during acute experimental autoimmune encephalomyelitisQ48589451
Immunolocalization of several laminin chains in the normal human central and peripheral nervous systemQ48664810
Tenascin C induces a quiescent phenotype in cultured adult human astrocytesQ48887150
Expression of neurocan after transient middle cerebral artery occlusion in adult rat brainQ48960921
Fibronectin and glial fibrillary acidic protein expression in normal human brain and anaplastic human gliomas.Q49074193
Chondroitin sulfate proteoglycans in spinal cord contusion injury and the effects of chondroitinase treatment.Q51728195
Upregulation of CSPG3 accompanies neuronal progenitor proliferation and migration in EAE.Q51894909
Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes.Q52172922
A role in migration for the alpha V beta 1 integrin expressed on oligodendrocyte precursors.Q52198957
Tenascin-C inhibits oligodendrocyte precursor cell migration by both adhesion-dependent and adhesion-independent mechanisms.Q52202135
Transplanted type-1 astrocytes facilitate repair of demyelinating lesions by host oligodendrocytes in adult rat spinal cord.Q52237036
Influence of glycosaminoglycans on neurite morphology and outgrowth patterns in vitroQ69228709
Identification of a cell-surface protein involved in PC12 cell-substratum adhesion and neurite outgrowth on laminin and collagenQ69357252
Experimental allergic encephalomyelitis (EAE): Delayed myelination-inhibitionin vitro with EAE-serum: Changes in vulnerability of oligodendroglia and newly formed myelin sheathsQ69566738
Nerve fiber growth in culture on fibronectin, collagen, and glycosaminoglycan substratesQ71073630
Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesionsQ71677421
Laminin and fibronectin promote the chemotaxis of human malignant plasma cell linesQ71860499
Multiple sclerosis: remyelination in acute lesionsQ72080198
Chondroitin sulfate proteoglycans are a common component of neuronal inclusions and astrocytic reaction in neurodegenerative diseasesQ72368172
Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelinationQ73265157
Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantationQ73343119
Brain derived versican V2 is a potent inhibitor of axonal growthQ73441516
Schwann cell remyelination is restricted to astrocyte-deficient areas after transplantation into demyelinated adult rat brainQ73812609
Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cordQ78003481
Chondroitinase ABC promotes axonal re-growth and behavior recovery in spinal cord injuryQ80242034
Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelinationQ81421491
Antibodies against the NG2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cordQ83282931
NG2 colocalizes with axons and is expressed by a mixed cell population in spinal cord lesionsQ83323945
P407language of work or nameEnglishQ1860
P921main subjectmyelinationQ14876135
P304page(s)39-46
P577publication date2013-11-04
P1433published inExperimental NeurologyQ5421127
P1476titleInhibitors of myelination: ECM changes, CSPGs and PTPs
P478volume251

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