| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M006933200 |
| P698 | PubMed publication ID | 11278322 |
| P2093 | author name string | Roy S | |
| Liu S | |||
| Mason J | |||
| Creemers JW | |||
| Tabibzadeh S | |||
| Ulloa L | |||
| P2860 | cites work | Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein | Q22008584 |
| Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. | Q22008848 | ||
| MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling | Q24310282 | ||
| Biosynthesis, distinct post-translational modifications, and functional characterization of lymphoma proprotein convertase | Q24320002 | ||
| Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding | Q24322303 | ||
| Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells | Q24656526 | ||
| Signal transduction by bone morphogenetic proteins | Q77163167 | ||
| Bone morphogenetic protein 2 inhibits platelet-derived growth factor-induced c-fos gene transcription and DNA synthesis in mesangial cells. Involvement of mitogen-activated protein kinase | Q77298347 | ||
| Bone morphogenetic protein-2 inhibits MAPK-dependent Elk-1 transactivation and DNA synthesis induced by EGF in mesangial cells | Q77754273 | ||
| ??? | Q22010493 | ||
| A structural basis for mutational inactivation of the tumour suppressor Smad4 | Q27740172 | ||
| TGF-beta signalling from cell membrane to nucleus through SMAD proteins | Q28131770 | ||
| Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor | Q28208226 | ||
| Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos | Q28276664 | ||
| lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal | Q28279904 | ||
| Smads: transcriptional activators of TGF-beta responses | Q28292325 | ||
| Processing of transforming growth factor beta 1 precursor by human furin convertase | Q28300881 | ||
| Left-right asymmetry and kinesin superfamily protein KIF3A: new insights in determination of laterality and mesoderm induction by kif3A-/- mice analysis | Q28512332 | ||
| Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice | Q28590964 | ||
| Expression cloning of Xantivin, a Xenopus lefty/antivin-related gene, involved in the regulation of activin signaling during mesoderm induction | Q30968694 | ||
| Downstream factors in transforming growth factor-beta family signaling | Q33534117 | ||
| Molecular motors: the driving force behind mammalian left-right development. | Q33826695 | ||
| Role of Ras and Mapks in TGFbeta signaling | Q33857574 | ||
| BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development | Q33889312 | ||
| Mechanisms of left-right determination in vertebrates | Q33897938 | ||
| Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. | Q34062451 | ||
| Signaling of transforming growth factor-beta family members through Smad proteins | Q34098846 | ||
| Mammalian subtilisins: the long-sought dibasic processing endoproteases | Q34130879 | ||
| Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. | Q36288112 | ||
| alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent | Q36485158 | ||
| Conservation of the prohormone convertase gene family in metazoa: analysis of cDNAs encoding a PC3-like protein from hydra | Q37116216 | ||
| Relationship between asymmetric nodal expression and the direction of embryonic turning | Q38357925 | ||
| Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathway | Q40874515 | ||
| Ontogeny of prohormone convertases in rat prenatal development | Q40897181 | ||
| Transforming growth factor-beta signaling in epithelial cells | Q40910677 | ||
| Transforming growth factor beta1 rescues serum deprivation-induced apoptosis via the mitogen-activated protein kinase (MAPK) pathway in macrophages | Q40962007 | ||
| Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway | Q41087152 | ||
| The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function | Q41119639 | ||
| Addition of a C-terminal extension sequence to transforming growth factor-beta 1 interferes with biosynthetic processing and abolishes biological activity | Q41132066 | ||
| Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. | Q41157114 | ||
| Identification of a transferable sorting domain for the regulated pathway in the prohormone convertase PC2. | Q41159207 | ||
| Transforming growth factor beta 1: importance of glycosylation and acidic proteases for processing and secretion | Q41945612 | ||
| Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus | Q43411996 | ||
| Neural induction by the secreted polypeptide noggin | Q44628705 | ||
| Molecular mechanisms of vertebrate left-right development. | Q52182135 | ||
| No turning, a mouse mutation causing left-right and axial patterning defects. | Q52190618 | ||
| The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness. | Q52193078 | ||
| Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. | Q52193097 | ||
| The developmental expression in the rat CNS and peripheral tissues of proteases PC5 and PACE4 mRNAs: comparison with other proprotein processing enzymes. | Q52196692 | ||
| A new spin on handed asymmetry | Q58995604 | ||
| Activin- and Nodal-related factors control antero–posterior patterning of the zebrafish embryo | Q59080120 | ||
| Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4 | Q72659550 | ||
| A role for bone morphogenetic proteins in the induction of cardiac myogenesis | Q73094521 | ||
| Left-right asymmetry in vertebrates | Q73728565 | ||
| P433 | issue | 24 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 21387-21396 | |
| P577 | publication date | 2001-02-20 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Lefty proteins exhibit unique processing and activate the MAPK pathway | |
| P478 | volume | 276 |
| Q44828936 | ALK4 functions as a receptor for multiple TGF beta-related ligands to regulate left-right axis determination and mesoderm induction in Xenopus |
| Q34233493 | Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse |
| Q54288360 | Expression and localization of nodal in bovine oviduct and uterus during different functional stages of oestrus cycle and pregnancy. |
| Q36670245 | Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells |
| Q36545901 | In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate |
| Q43959143 | Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion |
| Q38569338 | LEFTY2 expression and localization in rat oviduct during early pregnancy. |
| Q27670456 | Latent TGF-β structure and activation |
| Q42687913 | Lefty Glycoproteins in Human Embryonic Stem Cells: Extracellular Delivery Route and Posttranslational Modification in Differentiation |
| Q44259972 | Lefty antagonism of Squint is essential for normal gastrulation |
| Q28208226 | Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor |
| Q43483068 | Left‐right determination factor is down‐regulated in fibrotic renal tissue of human hydronephrosis |
| Q34271462 | Nodal Signaling in Vertebrate Development |
| Q34889525 | Nodal and lefty signaling regulates the growth of pancreatic cells |
| Q38823276 | Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily |
| Q44127959 | Regulation and function of LEFTY-A/EBAF in the human endometrium. mRNA expression during the menstrual cycle, control by progesterone, and effect on matrix metalloprotineases |
| Q38361357 | Structure-function analysis of the prosegment of the proprotein convertase PC5A. |
| Q52013254 | Subtilisin-like proprotein convertase activity is necessary for left-right axis determination in Xenopus neurula embryos. |
| Q40379230 | The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases |
| Q44279243 | The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1. |
| Q46881400 | The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates |
| Q33643238 | Transforming growth factor-beta1 attenuates expression of both the progesterone receptor and Dickkopf in differentiated human endometrial stromal cells |
| Q24318787 | VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5 |
| Q48788926 | Xenopus Lefty requires proprotein cleavage but not N-linked glycosylation to inhibit nodal signaling |
| Q88912566 | miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancer |
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