Malaria vaccine: roadblocks and possible solutions

scientific article

Malaria vaccine: roadblocks and possible solutions is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1590/S0100-879X1998000300002
P698PubMed publication ID9698780

P2093author name stringM M Rodrigues
I S Soares
P2860cites workProtection against malaria by immunization with plasmid DNA encoding circumsporozoite proteinQ24563514
The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytesQ29393314
Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytesQ29618991
Immunization of Aotus monkeys with Plasmodium falciparum blood-stage recombinant proteinsQ33598899
The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoitesQ34237481
Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand. Shoklo SPf66 Malaria Vaccine Trial GroupQ34397061
Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malariaQ34620173
The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion moleculesQ36231136
Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malariaQ36343961
A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.Q36352078
Malaria vaccine trials: the missing qualitative dataQ36827211
The effect of insecticide-treated bed nets on mortality of Gambian childrenQ38870607
Efficacy trial of malaria vaccine SPf66 in Gambian infantsQ38959070
Dimorphism of the C terminus of the Plasmodium vivax merozoite surface protein 1.Q39340864
Liposomes as Carriers of Peptide Antigens: Induction of Antibodies and Cytotoxic T Lymphocytes to Conjugated and Unconjugated PeptidesQ40433315
Randomised trial of efficacy of SPf66 vaccine against Plasmodium falciparum malaria in children in southern Tanzania.Q40694949
Malaria vaccines: multiple targetsQ40695819
T cell responses to pre-erythrocytic stages of malaria: role in protection and vaccine development against pre-erythrocytic stagesQ40898245
The role of TH1 and TH2 cells in a rodent malaria infection.Q41546942
Recombinant Pfs25 protein of plasmodium falciparum elicits malaria transmission-blocking immunity in experimental animalsQ42006764
Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytesQ42938913
Induction of plasmodium falciparum transmission-blocking antibodies by recombinant vaccinia virusQ43409506
Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoitesQ44146544
A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation GroupQ44174498
Circumsporozoite protein is required for development of malaria sporozoites in mosquitoesQ44174540
CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malariaQ47863985
Oral Salmonella typhimurium vaccine expressing circumsporozoite protein protects against malariaQ47910752
Immunization against blood-stage rodent malaria using purified parasite antigensQ47996405
Target antigens for asexual malaria vaccine developmentQ47996640
The combined epidermal growth factor-like modules of Plasmodium yoelii Merozoite Surface Protein-1 are required for a protective immune response to the parasiteQ47998652
Monoclonal antibodies that inhibit Plasmodium falciparum invasion in vitro recognise the first growth factor-like domain of merozoite surface protein-1.Q48002865
Safety, immunogenicity, and efficacy of a recombinantly produced Plasmodium falciparum circumsporozoite protein-hepatitis B surface antigen subunit vaccineQ48004555
Salmonella typhi vaccine strain CVD 908 expressing the circumsporozoite protein of Plasmodium falciparum: strain construction and safety and immunogenicity in humans.Q48014958
Identification and characterization of the protective hepatocyte erythrocyte protein 17 kDa gene of Plasmodium yoelii, homolog of Plasmodium falciparum exported protein 1.Q48028231
Proteolytic processing of the Plasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domainsQ48202726
Characterization ofin VivoPrimary and Secondary CD8+T Cell Responses Induced by Recombinant Influenza and Vaccinia VirusesQ56877444
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
malaria vaccineQ6741353
P304page(s)317-332
P577publication date1998-03-01
P1433published inBrazilian Journal of Medical and Biological ResearchQ2025772
P1476titleMalaria vaccine: roadblocks and possible solutions
P478volume31

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cites work (P2860)
Q47893571Comparison of the immunogenic properties of recombinant proteins representing the Plasmodium vivax vaccine candidate MSP1(19) expressed in distinct bacterial vectors
Q43733553Homology modeling of wild type and pyrimethamine/cycloguanil-cross resistant mutant type Plasmodium falciparum dihydrofolate reductase. A model for antimalarial chemotherapy resistance
Q34070173Transfectant influenza viruses as antigen delivery vectors

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