Expression of the type I diabetes-associated gene LRP5 in macrophages, vitamin A system cells, and the Islets of Langerhans suggests multiple potential roles in diabetes

scientific article published on October 2000

Expression of the type I diabetes-associated gene LRP5 in macrophages, vitamin A system cells, and the Islets of Langerhans suggests multiple potential roles in diabetes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/002215540004801006
P698PubMed publication ID10990489
P5875ResearchGate publication ID12331624

P2093author name stringJ F Hess
C P Austin
D J Figueroa
J A Todd
V Sandig
S D Brown
R C Twells
A Hermanowski-Vosatka
B Ky
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Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1)Q28240779
A genome-wide search for human type 1 diabetes susceptibility genesQ28247197
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Cloning of a novel member of the low-density lipoprotein receptor familyQ28280437
Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8Q28285936
Comparative genetics of type 1 diabetes and autoimmune disease: common loci, common pathways?Q33676601
Lipoprotein receptors: new roles for ancient proteins.Q33772665
Fine mapping of the diabetes-susceptibility locus, IDDM4, on chromosome 11q13.Q34386630
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.Q34452348
An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.Q35748116
I-E+ nonobese diabetic mice develop insulitis and diabetesQ36362338
Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasisQ37412523
Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).Q40643050
Vitamin A homeostasis and diabetes mellitusQ41588881
Vitamin A status affects the development of diabetes and insulitis in BB ratsQ45291718
Molecular mechanisms in the reversible regulation of morphology, proliferation and collagen metabolism in hepatic stellate cells by the three-dimensional structure of the extracellular matrixQ47672456
A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E.Q48004911
Further evidence linking late-onset Alzheimer disease with chromosome 12.Q53226396
Genetic association studies between Alzheimer's disease and two polymorphisms in the low density lipoprotein receptor-related protein gene.Q53329766
P433issue10
P921main subjecttype-1 diabetesQ124407
vitamin AQ18225
P304page(s)1357-1368
P577publication date2000-10-01
P1433published inJournal of Histochemistry and CytochemistryQ1523992
P1476titleExpression of the type I diabetes-associated gene LRP5 in macrophages, vitamin A system cells, and the Islets of Langerhans suggests multiple potential roles in diabetes
P478volume48

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cites work (P2860)
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Q36475048LRP5 variants may contribute to ADPKD
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