Bcl-X(L) antisense sensitizes human colon cancer cell line to 5-fluorouracil

scientific article published on August 2000

Bcl-X(L) antisense sensitizes human colon cancer cell line to 5-fluorouracil is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1349-7006.2000.TB01020.X
P932PMC publication ID5926420
P698PubMed publication ID10965024
P5875ResearchGate publication ID246815338

P2093author name stringY Nakamura
H Nagawa
S K Ono-Nita
J Kitayama
N Tsuno
M E Nita
O Tominaga
E Sunami
T Takenoue
P2860cites work5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteinsQ28369128
Drug-target interactions: only the first step in the commitment to a programmed cell death?Q37188769
The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotidesQ38326195
Bcl-2 overexpression results in reciprocal downregulation of Bcl-X(L) and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosisQ40970064
Modulation of apoptosis by endogenous Bcl-xL expression in MKN-45 human gastric cancer cellsQ40990396
Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.Q41132569
30 KDa phosphorylated form of Bcl-2 protein in human colonQ41190957
Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosisQ41335047
Antisense oligonucleotides as therapeutics for malignant diseases.Q41454086
Bcl-2 inhibits chemotherapy-induced apoptosis in neuroblastoma.Q41461017
Inhibition of Bcl-xL expression sensitizes normal human keratinocytes and epithelial cells to apoptotic stimuliQ41684512
Role of apoptotic response in cellular resistance to cytotoxic agentsQ41735655
Antiapoptosis potential of bcl-2 oncogene by dephosphorylationQ42277594
bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways.Q42505657
Elevated expression of Bcl-X and reduced Bak in primary colorectal adenocarcinomas.Q44486888
Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosisQ45859903
Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease.Q45997933
Gene inhibition using antisense oligodeoxynucleotidesQ46429559
Problems in interpretation of data derived from in vitro and in vivo use of antisense oligodeoxynucleotidesQ72779505
Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell deathQ73555365
bcl-2 antisense therapy chemosensitizes human melanoma in SCID miceQ74165698
BCL-2 gene family and the regulation of programmed cell deathQ77303933
P433issue8
P921main subjectcolon cancerQ18555025
cancer cell lineQ23058136
P1104number of pages8
P304page(s)825-832
P577publication date2000-08-01
P1433published inJapanese Journal of Cancer ResearchQ26842384
P1476titleBcl-X(L) antisense sensitizes human colon cancer cell line to 5-fluorouracil
P478volume91

Reverse relations

cites work (P2860)
Q35416266Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells
Q36795425Apoptosis and chemo-resistance in colorectal cancer
Q36671167Bcl-xL antisense oligonucleotides radiosensitise colon cancer cells
Q41828839Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway
Q38361912Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents
Q35085222Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells
Q46550944Expression of pro-apoptotic Bfk isoforms reduces during malignant transformation in the human gastrointestinal tract
Q35841071Molecular aspects of esophageal squamous cell carcinoma carcinogenesis
Q34564963Molecular aspects of hepatic carcinogenesis
Q45855025Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kappaB and upregulation of BCL-2 and BCL-XL.
Q30971455Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family
Q43938032Resistance of colon cancer cells to long-term 5-fluorouracil exposure is correlated to the relative level of Bcl-2 and Bcl-X(L) in addition to Bax and p53 status

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