Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.

scientific article published on November 2000

Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M002970200
P698PubMed publication ID10906125
P5875ResearchGate publication ID12413568

P2093author name stringS C Sun
G Xiao
E W Harhaj
P2860cites workIdentification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosisQ22008750
I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA bindingQ24307786
The NF-kappa B and I kappa B proteins: new discoveries and insightsQ24313579
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complexQ24316469
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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176Q24319941
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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activationQ47964174
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IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complexQ24530641
Activation of IkappaB kinase beta by protein kinase C isoformsQ24554525
MEKK1 activates both IkappaB kinase alpha and IkappaB kinase betaQ24681806
Predicting coiled coils from protein sequencesQ27861097
Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathwayQ28302102
Function and activation of NF-kappa B in the immune systemQ29547790
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphomaQ29615115
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activationQ29617419
Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax.Q30417542
Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complexQ33663188
An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300Q33777090
Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinasesQ33777633
How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complexQ33797139
Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinasesQ33797174
PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent mannerQ33960604
Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300Q33996796
Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the diseaseQ34274473
A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virusQ34564449
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1Q36004058
The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.Q36063657
Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interactionQ37135126
Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemiaQ37648645
Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancerQ37649857
HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerizationQ38315223
The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B functionQ38338301
Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradationQ40018360
Ionizing radiation activates the ATM kinase throughout the cell cycleQ40893193
Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel geneQ41431590
Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypesQ41715443
Signal transduction through NF-kappa B.Q41724478
Recombinant IkappaB kinases alpha and beta are direct kinases of Ikappa BalphaQ42059788
Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulationQ43574038
IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax proteinQ45747947
IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.Q45749335
NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activationQ45754430
The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbetaQ45755453
Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax.Q45787620
P433issue44
P407language of work or nameEnglishQ1860
P304page(s)34060-34067
P577publication date2000-11-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleDomain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.
P478volume275

Reverse relations

cites work (P2860)
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