MicroRNA-9 promotes proliferation of leukemia cells in adult CD34-positive acute myeloid leukemia with normal karyotype by downregulation of Hes1.

scientific article published on 17 December 2015

MicroRNA-9 promotes proliferation of leukemia cells in adult CD34-positive acute myeloid leukemia with normal karyotype by downregulation of Hes1. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1028907553
P356DOI10.1007/S13277-015-4581-X
P698PubMed publication ID26678889

P50authorGuoguang ZhengQ49885423
P2093author name stringLei Zhu
Yong Yu
Chen Tian
M James You
Yizhuo Zhang
P2860cites workTargeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancerQ24307748
Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer TherapyQ24337757
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastomaQ27350129
MicroRNA-9 Modulates Hes1 ultradian oscillations by forming a double-negative feedback loopQ33920068
Hes1 is a target of microRNA-23 during retinoic-acid-induced neuronal differentiation of NT2 cellsQ34206217
Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs.Q34230583
Identification and targeting leukemia stem cells: The path to the cure for acute myeloid leukemiaQ34232877
Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cellsQ34421127
Proteomic profiling identifies distinct protein patterns in acute myelogenous leukemia CD34+CD38- stem-like cellsQ35040064
Regulation of cancer metastasis by microRNAsQ35052860
HES1 is an independent prognostic factor for acute myeloid leukemiaQ35541938
Hes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environmentQ36618643
Preferential eradication of acute myelogenous leukemia stem cells by fenretinideQ36747742
miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.Q37010564
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signalingQ37101484
Normal hematopoietic stem cells within the AML bone marrow have a distinct and higher ALDH activity level than co-existing leukemic stem cellsQ37297755
Targeting of leukemia-initiating cells to develop curative drug therapies: straightforward but nontrivial concept.Q37808236
Identification of leukemia stem cells in acute myeloid leukemia and their clinical relevanceQ38010349
Identifying leukemia stem cells--is it feasible and does it matter?Q38028260
Acute myeloid leukemia in adolescents and young adults: challenging aspectsQ38250288
MicroRNAs expressed in hematopoietic stem/progenitor cells are deregulated in acute myeloid leukemiasQ38252974
Notch activation inhibits AML growth and survival: a potential therapeutic approachQ39202885
Resistance of leukemic stem-like cells in AML cell line KG1a to natural killer cell-mediated cytotoxicityQ39422497
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.Q39782714
Hes1 suppresses acute myeloid leukemia development through FLT3 repressionQ42186875
Attenuation of microRNA-126 expression that drives CD34+38- stem/progenitor cells in acute myeloid leukemia leads to tumor eradicationQ43806378
Identification and separation of normal hematopoietic stem cells and leukemia stem cells from patients with acute myeloid leukemiaQ45216078
Leukemia stem cellsQ46509360
miR-9 is a tumor suppressor in pediatric AML with t(8;21).Q48336259
A 3-microRNA scoring system for prognostication in de novo acute myeloid leukemia patients.Q50609353
Mouse microRNA-23b regulates expression of Hes1 gene in P19 cells.Q51097380
A miRNA Signature in Human Cord Blood Stem and Progenitor Cells as Potential Biomarker of Specific Acute Myeloid Leukemia Subtypes.Q54180550
HES1 activation suppresses proliferation of leukemia cells in acute myeloid leukemiaQ85410943
P433issue6
P921main subjectkaryotypeQ189967
acute myeloid leukemiaQ264118
microRNAQ310899
leukemiaQ29496
P304page(s)7461-7471
P577publication date2015-12-17
P1433published inTumor BiologyQ15757842
P1476titleMicroRNA-9 promotes proliferation of leukemia cells in adult CD34-positive acute myeloid leukemia with normal karyotype by downregulation of Hes1.
P478volume37

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