Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches

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Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches is …
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review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1001381566
P356DOI10.2165/00003495-199754050-00002
P698PubMed publication ID9360056

P2093author name stringPerfect JR
Alexander BD
P2860cites workSelection of Candida glabrata in pediatric bone marrow transplant recipients receiving fluconazoleQ72520371
Candida glabrata, Candida krusei, non-albicans Candida spp., and other fungal organisms in a sixty-bed national cancer center in 1989-1993: no association with the use of fluconazoleQ72588936
Role of granulocyte-macrophage colony-stimulating factor as adjuvant therapy for fungal infection in patients with cancerQ72675254
Resistance to amphotericin B associated with defective sterol delta 8-->7 isomerase in a Cryptococcus neoformans strain from an AIDS patientQ72800846
Long-term follow-up of patients with invasive fungal disease who received adjunctive therapy with recombinant human macrophage colony-stimulating factorQ72909151
Stable azole drug resistance associated with a substrain of Candida albicans from an HIV-infected patientQ74145459
Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungalsQ28293585
Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivoQ28316948
Topical pharmacology of imidazole antifungalsQ28333823
In vitro activity of itraconazole against fluconazole-susceptible and -resistant Candida albicans isolates from oral cavities of patients infected with human immunodeficiency virusQ28369094
In vitro and in vivo efficacies of the azole SCH56592 against Cryptococcus neoformansQ28379195
Multiple efflux mechanisms are involved in Candida albicans fluconazole resistanceQ28379619
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Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance geneQ33752151
Azole resistance in oropharyngeal Candida albicans strains isolated from patients infected with human immunodeficiency virusQ33762325
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Antifungal agents: chemotherapeutic targets and immunologic strategiesQ34400044
Resistance of Candida species to fluconazoleQ35110522
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Correlation of in-vitro susceptibility test results with clinical response: a study of azole therapy in AIDS patients.Q54172080
Antifungal prophylaxis with low-dose fluconazole during bone marrow transplantation. The Bone Marrow Transplantation Team.Q54190673
Clinically significant mucosal candidiasis resistant to fluconazole treatment in patients with AIDS.Q54194571
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HIV and multidrug resistanceQ54233451
Foscarnet treatment of cytomegalovirus gastrointestinal infections in acquired immunodeficiency syndrome patients who have failed ganciclovir induction.Q54244016
Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase.Q54390050
The lipid composition of azole-sensitive and azole-resistant strains of Candida albicans.Q54423176
Azole resistance in Candida albicans.Q54484937
Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients.Q54503124
Mode of Action of 5-Fluorocytosine and Mechanisms of ResistanceQ54631149
In vivo interferon-gamma therapy augments the in vitro ability of chronic granulomatous disease neutrophils to damage Aspergillus hyphaeQ57908432
Pradimicin, a novel class of potent antifungal antibioticsQ67980659
Amphotericin B-resistant yeast infection in severely immunocompromised patientsQ68136440
5-Fluorocytosine resistance in Candida spp. and Torulopsis glabrataQ69260125
Fatal disseminated candidiasis due to amphotericin-B-resistant Candida guilliermondiiQ70047840
Correlation of in Vitro Susceptibility Test Results with in Vivo Response: Flucytosine Therapy in a Systemic Candidiasis ModelQ70257684
In-vitro resistance to imidazole antifungals in Candida albicansQ70375025
Antifungal prophylaxis: to prevent or notQ70606608
Fluconazole-resistant Candida albicans after long-term suppressive therapyQ70677847
The Development Of Resistance By Candida Species To Polyene Antibiotics In VitroQ71153462
Serum therapy for Cryptococcal meningitisQ71373532
Cytomegalovirus encephalitis resistant to anti-cytomegalovirus therapyQ71971314
Infection due to fluconazole-resistant Candida in patients with AIDS: prevalence and microbiologyQ71972430
Correlation between in vitro susceptibility of Candida albicans and fluconazole-resistant oropharyngeal candidiasis in HIV-infected patientsQ72430003
Comparative and collaborative evaluation of standardization of antifungal susceptibility testing for filamentous fungiQ35111403
Cross-resistance to polyene and azole drugs in Cryptococcus neoformansQ35116225
Use of amphotericin B with azole antifungal drugs: what are we doing?Q35117932
Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transportersQ35120105
Correlation between rhodamine 123 accumulation and azole sensitivity in Candida species: possible role for drug efflux in drug resistance.Q35122459
Fungal virulence genes as targets for antifungal chemotherapy.Q35125420
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitorsQ35127954
Reduced accumulation of drug in Candida krusei accounts for itraconazole resistanceQ35128677
Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemiaQ35131728
Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virusQ35137093
In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important moldsQ35137879
5-fluorocytosine resistance in Cryptococcus neoformansQ35650214
Susceptibility to 5-fluorocytosine and prevalence of serotype in 402 Candida albicans isolates from the United StatesQ35716914
Candida albicans resistance to 5-fluorocytosine: frequency of partially resistant strains among clinical isolatesQ35761208
Modulation of host defenses by cytokines: evolving adjuncts in prevention and treatment of serious infections in immunocompromised hostsQ35811363
Association of Torulopsis glabrata infections with fluconazole prophylaxis in neutropenic bone marrow transplant patientsQ35819117
Correlation of in vitro fluconazole resistance of Candida isolates in relation to therapy and symptoms of individuals seropositive for human immunodeficiency virus type 1.Q35900199
Susceptibility testing of fungi: current status of the standardization processQ35903839
Treatment of acyclovir-resistant herpes simplex virus infections in patients with AIDSQ36197267
Development of Resistance to Amphotericin B in Candida lusitaniae Infecting a HumanQ36482211
Susceptibility testing of fungi: current status of correlation of in vitro data with clinical outcomeQ36528018
Genetic and Physiological Aspects of Resistance to 5-Fluoropyrimidines in Saccharomyces cerevisiaeQ36778878
Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole, and candida infections. Subcommittee on Antifungal Susceptibility TeQ36855581
Emergence of fluconazole-resistant strains of Candida albicans in patients with recurrent oropharyngeal candidosis and human immunodeficiency virus infection.Q37091074
Candida albicans genotyping in studies with patients with AIDS developing resistance to fluconazole.Q37141720
Fluconazole-resistant recurrent oral candidiasis in human immunodeficiency virus-positive patients: persistence of Candida albicans strains with the same genotype.Q37166301
Trichosporon beigelii, an emerging pathogen resistant to amphotericin BQ37186512
Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysisQ37195950
Collaborative comparison of broth macrodilution and microdilution antifungal susceptibility testsQ37251197
Fungal infections and the search for novel antifungal agents. Opening remarksQ39554263
FlucytosineQ39618637
The genetic basis of resistance to 5-fluorocytosine in Candida species and Cryptococcus neoformansQ39685110
Anti-Candida drugs--the biochemical basis for their activityQ39685115
Trichosporonosis in patients with neoplastic diseaseQ39737308
The genetics of medically important fungiQ39761162
Fluconazole resistance due to energy-dependent drug efflux in Candida glabrataQ39780155
The presence of an R467K amino acid substitution and loss of allelic variation correlate with an azole-resistant lanosterol 14alpha demethylase in Candida albicansQ39784510
Reduced virulence of Candida albicans mutants affected in multidrug resistanceQ39823514
Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbitsQ39851052
Uptake of itraconazole by alveolar macrophagesQ39865724
Susceptibilities of serial Cryptococcus neoformans isolates from patients with recurrent cryptococcal meningitis to amphotericin B and fluconazoleQ39866233
Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformansQ39881922
Characterization of an azole-resistant Candida glabrata isolateQ40088759
Fatal septicemia due to amphotericin B-resistant Candida lusitaniae.Q40216477
Development of amphotericin B-resistant Candida tropicalis in a patient with defective leukocyte functionQ40354286
Sterol content and polyene antibiotic resistance in isolates of Candida krusei, Candida parakrusei, and Candida tropicalisQ40647196
Genetics and biochemistry of yeast multidrug resistanceQ40696620
Is there a correlation between serum antifungal drug concentration and clinical outcome?Q40698229
Cryptococcal meningitis and AIDS.Q40803349
Fungal infections in solid-organ transplantationQ40914902
Lipid formulations of amphotericin B: recent progress and future directionsQ40941280
In Vitro Studies of 5-Fluorocytosine Resistance in Candida albicans and Torulopsis glabrataQ41028056
Management of invasive candidal infections: results of a prospective, randomized, multicenter study of fluconazole versus amphotericin B and review of the literatureQ41218000
Fungal infections in lung and heart-lung transplant recipients. Report of 9 cases and review of the literature.Q41269382
Defective sterol C5-6 desaturation and azole resistance: a new hypothesis for the mode of action of azole antifungalsQ41273819
Disseminated zygomycosis in a neutropenic patient: successful treatment with amphotericin B lipid complex and granulocyte colony-stimulating factorQ41440833
A comparative review of colony-stimulating factorsQ41634907
A Comparison of Amphotericin B Alone and Combined with Flucytosine in the Treatment of Cryptoccal MeningitisQ41644134
ATP-binding properties of P glycoprotein from multidrug-resistant KB cells.Q42202109
The lipid composition and permeability to azole of an azole- and polyene-resistant mutant of Candida albicansQ42217506
Correlation between in vitro and in vivo activity of antifungal agents against Candida speciesQ42283580
Correlation of in vitro azole susceptibility with in vivo response in a murine model of cryptococcal meningitisQ42287986
Correlation between antifungal susceptibility testing of Candida isolates from patients with HIV infection and clinical results after treatment with fluconazoleQ42600087
Zidovudine-resistant HIV strains in intravenous drug users and homosexual men in AmsterdamQ43419846
Increase inCandida kruseiInfection among Patients with Bone Marrow Transplantation and Neutropenia Treated Prophylactically with FluconazoleQ43543160
Oropharyngeal yeast flora and fluconazole resistance in HIV-infected patients receiving long-term continuous versus intermittent fluconazole therapy.Q43702464
Occurrence and characterization of acyclovir‐resistant herpes simplex virus isolates: Report on a two—year sensitivity screening surveyQ44354849
Comparative morphological and biological studies on the itraconazole- and ketoconazole-resistant mutants of Cryptococcus neoformansQ44532060
Visceral fungal infections due to Petriellidium boydii (allescheria boydii). In vitro drug sensitivity studiesQ44553558
Emergence of azole drug resistance in Candida species from HIV-infected patients receiving prolonged fluconazole therapy for oral candidosisQ44757473
Epidemiology of oral candidiasis in HIV-infected patients: colonization, infection, treatment, and emergence of fluconazole resistanceQ44986554
Risk factors for fluconazole-resistant candidiasis in human immunodeficiency virus-infected patientsQ45254690
Patterns of fluconazole susceptibility in isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis due to Candida albicansQ45763707
Detection and significance of fluconazole resistance in oropharyngeal candidiasis in human immunodeficiency virus-infected patientsQ45767645
A Mutation in Human Immunodeficiency Virus Reverse Transcriptase and Decline in CD4 Lymphocyte Numbers in Long-Term Zidovudine RecipientsQ45787062
Fluconazole combined with flucytosine for treatment of cryptococcal meningitis in patients with AIDS.Q46047518
Azole resistance in Candida albicans.Q46470040
René Dubos: a harbinger of microbial resistance to antibioticsQ48853971
Resistance to polyene antibiotics and correlated sterol changes in two isolates of Candida tropicalis from a patient with an amphotericin B-resistant funguria.Q53743852
Development of strains of Cryptococcus neoformans resistant to nystatin, amphotericin B, trichomycin and polymyxin B.Q54029821
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)657-678
P577publication date1997-11-01
P1433published inDrugsQ3040094
P1476titleAntifungal resistance trends towards the year 2000. Implications for therapy and new approaches
P478volume54

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