Biosynthesis of the Vacuolar Yeast Glycoprotein Carboxypeptidase Y. Conversion of Precursor into the Enzyme

scientific article published on April 17, 1978

Biosynthesis of the Vacuolar Yeast Glycoprotein Carboxypeptidase Y. Conversion of Precursor into the Enzyme is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1432-1033.1978.TB12275.X
P953full work available at URLhttp://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1432-1033.1978.tb12275.x/fullpdf
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1432-1033.1978.tb12275.x
P698PubMed publication ID348476
P5875ResearchGate publication ID229643343

P2093author name stringW. Tanner
A. Hasilik
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myelomaQ24681545
Intracellular Aspects of the Process of Protein SynthesisQ29615237
A possible precursor of immunoglobulin light chainsQ34211267
In vitro synthesis and processing of a putative precursor for the small subunit of ribulose-1,5-bisphosphate carboxylase of Chlamydomonas reinhardtiiQ35011504
Isolation and Characterization of the Carboxypeptidase Y Inhibitor from YeastQ35120115
The role of organelles in the chemical modification of the primary translation products of secretory proteinsQ36356972
Regulation of Factors that Influence the In Vitro Stability of Tryptophan Synthetase from YeastQ36849589
Homology in amino-terminal sequence of precursors to pancreatic secretory proteinsQ37465709
Tunicamycin inhibition of polyisoprenyl N-acetylglucosaminyl pyrophosphate formation in calf-liver microsomesQ39941150
Autoradiographic Study of Mannan Incorporation into the Growing Cell Walls of Saccharomyces cerevisiaeQ40094293
Proteolytic activities in yeastQ40319942
Inhibition of the apparent rate of synthesis on the vacuolar glycoprotein carboxypeptidase Y and its protein antigen by tunicamycin in Saccharomyces cerevisiaeQ40947244
Intracellular transport of secretory proteins in the pancreatic exocrine cell. II. Transport to condensing vacuoles and zymogen granulesQ41096456
Radioautographic study of in vivo and in vitro incorporation of fucose-3H into thyroglobulin by rat thyroid follicular cellsQ41144696
Biosynthesis of carboxypeptidase Y in yeast. Evidence for a precursor form of the glycoproteinQ43731350
Compartmentation of the tryptophan-synthase-proteolyzing system in Saccharomyces cerevisiaeQ44988105
Immediate glycosylation of Sindbis virus membrane proteinsQ45890635
Purification and Properties of Tryptophan-Synthase-Inactivating Enzymes from YeastQ54128960
Activities and cellular localization of yeast proteases and their inhibitorsQ54188004
The specific site of tunicamycin inhibition in the formation of dolichol-bound N-acetylglucosamine derivativesQ67496678
Comparisons of the Tryptophan Synthase Inactivating Enzymes with Proteinases from YeastQ69348969
Isolation and partial characterization of an acid carboxypeptidase from yeastQ69357114
Compartmentation of inhibitors of proteinases A and B and carboxypeptidase Y in yeastQ69361091
A unique carboxypeptidase activity of yeast proteinase CQ71526171
[5] Molecular weight determination of glycoproteins by polyacrylamide gel electrophoresis in sodium dodecyl sulfateQ115926558
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectbiochemistryQ7094
P304page(s)599-608
P577publication date1978-04-01
1978-04-17
P1433published inFEBS JournalQ1388041
P1476titleBiosynthesis of the Vacuolar Yeast Glycoprotein Carboxypeptidase Y. Conversion of Precursor into the Enzyme
P478volume85

Reverse relations

cites work (P2860)
Q38751290A hitchhiker's guide to analysis of the secretory pathway in yeast
Q50420468A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae
Q33327846A putative zinc finger protein, Saccharomyces cerevisiae Vps18p, affects late Golgi functions required for vacuolar protein sorting and efficient alpha-factor prohormone maturation
Q27930427Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway
Q42638535Analysis of the DNA sequence of a 15,500 bp fragment near the left telomere of chromosome XV from Saccharomyces cerevisiae reveals a putative sugar transporter, a carboxypeptidase homologue and two new open reading frames
Q50672474Analysis of the vacuolar luminal proteome of Saccharomyces cerevisiae.
Q36408440Asparagine-linked carbohydrate does not determine the cellular location of yeast vacuolar nonspecific alkaline phosphatase
Q41441307Assembly of storage protein oligomers in the endoplasmic reticulum and processing of the polypeptides in the protein bodies of developing pea cotyledons
Q28303811BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast
Q35507419Biogenesis of the vacuole in Saccharomyces cerevisiae
Q41107319Biogenesis of the yeast lysosome (vacuole): biosynthesis and maturation of proteinase yscB
Q47853001Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II.
Q43736262Biosynthesis of a lysosomal enzyme. Partial structure of two transient and functionally distinct NH2-terminal sequences in cathepsin D
Q40977470Carbohydrate Moiety of Carboxypeptidase Y and Perturbation of Its Biosynthesis
Q27933503Cdk1-dependent control of membrane-trafficking dynamics.
Q33569803Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae
Q33564532Characterization of the END1 gene required for vacuole biogenesis and gluconeogenic growth of budding yeast
Q34054304Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis
Q40266220Comparative biochemistry of the proteinases of eucaryotic microorganisms
Q40217815Control of metabolism in yeast and other lower eukaryotes through action of proteinases
Q81367708Effect of ethanol on the production of carboxypeptidase Y using the GAL10 promoter in a Saccharomyces cerevisiae gal80 mutant
Q27933262Endocytosis in yeast: evidence for the involvement of a small GTP-binding protein (Ypt7p)
Q36214972Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y.
Q33948951Genetic properties of mutations at the PEP4 locus in Saccharomyces cerevisiae.
Q27933135Golgi-mediated glycosylation determines residency of the T2 RNase Rny1p in Saccharomyces cerevisiae
Q36232736Guanosine diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae
Q42795634Identification of novel vesicles in the cytosol to vacuole protein degradation pathway
Q40367879Immature Core protein of hepatitis C virus induces an unfolded protein response through inhibition of ERAD-L in a yeast model system
Q36224257In vitro reconstitution of intercompartmental protein transport to the yeast vacuole
Q36788886Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information
Q36695332Isolation and characterization of cDNA clones encoding jacalin isolectins
Q41968579Isolation of degradation-deficient mutants defective in the targeting of fructose-1,6-bisphosphatase into the vacuole for degradation in Saccharomyces cerevisiae.
Q29615734Isolation of yeast mutants defective in protein targeting to the vacuole
Q70368144Localization of the thermosensitive X-prolyl dipeptidyl aminopeptidase in the vacuolar membrane of Saccharomyces cerevisiae
Q41346111Maturation of vacuolar (lysosomal) enzymes in yeast: proteinase yscA and proteinase yscB are catalysts of the processing and activation event of carboxypeptidase yscY.
Q27938078Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase
Q27939237Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle
Q35309290Mutant defective in processing of an enzyme located in the lysosome-like vacuole of Saccharomyces cerevisiae
Q40241598Mutation of a tyrosine localization signal in the cytosolic tail of yeast Kex2 protease disrupts Golgi retention and results in default transport to the vacuole
Q37601974Mutations in PEP4 locus of Saccharomyces cerevisiae block final step in maturation of two vacuolar hydrolases
Q36219420Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting
Q34162725PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors
Q52566665Process development for industrial-scale preparation of carboxypeptidase Y secreted by Saccharomyces cerevisiae.
Q37610289Propeptide of carboxypeptidase Y provides a chaperone-like function as well as inhibition of the enzymatic activity
Q27937990Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases
Q37140672Protein transport and compartmentation in yeast
Q72590851Proteolysis in eukaryotic cells. Identification of multiple proteolytic enzymes in yeast
Q41909120Recycling of proteins from the Golgi compartment to the ER in yeast
Q67527490Regulated overproduction and secretion of yeast carboxypeptidase Y
Q27932182Review: biosynthesis and function of yeast vacuolar proteases
Q27930142Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex
Q36234823Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast
Q70324846Specific processing of the bacterial ?-lactamase precursor in Saccharomyces cerevisiae
Q27937407Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum
Q27937962Studies on a Proteinase B Mutant of Yeast
Q33939830Subcellular site of lectin synthesis in developing rice embryos
Q70280482Synthesis and maturation of the yeast vacuolar enzymes carboxypeptidase Y and aminopeptidase I
Q72547313Synthesis and possible role of carbohydrate moieties of yeast glycoproteins
Q77105464The C terminus of the Vps34p phosphoinositide 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase
Q27930186The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants
Q37695497The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.
Q24634743The fungal vacuole: composition, function, and biogenesis
Q79300541The propeptide in the precursor form of carboxypeptidase Y ensures cooperative unfolding and the carbohydrate moiety exerts a protective effect against heat and pressure
Q42574320The proteolytic landscape of the yeast vacuole
Q27935902The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution
Q36777557Theearly andlate processing of lysosomal enzymes: Proteolysis and compartmentation
Q34337565Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization
Q27939685Vid24p, a novel protein localized to the fructose-1, 6-bisphosphatase-containing vesicles, regulates targeting of fructose-1,6-bisphosphatase from the vesicles to the vacuole for degradation
Q36223409Yeast carboxypeptidase Y vacuolar targeting signal is defined by four propeptide amino acids.
Q40898883Yeast extracellular proteases
Q36209637Yeast secretory mutants that block the formation of active cell surface enzymes