High-yield production of a human therapeutic protein in tobacco chloroplasts

scientific article

High-yield production of a human therapeutic protein in tobacco chloroplasts is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/73796
P698PubMed publication ID10700152
P5875ResearchGate publication ID12615841

P2093author name stringWard D
Carroll JA
Russell DA
Hunter P
Graves J
Garcia B
Staub JM
Ye G
Hajdukiewicz PT
Nehra N
Spatola L
Paradkar V
Schlittler M
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Rapid verification of disulfide linkages in recombinant human growth hormone by tandem column tryptic mappingQ32057849
Stable transformation of plastids in higher plantsQ33876575
Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plantsQ34849268
Efficient targeting of foreign genes into the tobacco plastid genomeQ34875754
High-frequency plastid transformation in tobacco by selection for a chimeric aadA geneQ36081161
Regulation of chloroplast enzyme activities by thioredoxins: activation or relief from inhibition?Q39439157
Structural Variants of Human Growth Hormone: Biochemical, Genetic, and Clinical AspectsQ40150815
Transgenic plants as vaccine production systemsQ40405033
Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.Q40760044
Low probability of chloroplast movement from oilseed rape (Brassica napus) into wild Brassica rapa.Q40816933
G120R, a human growth hormone antagonist, shows zinc-dependent agonist and antagonist activity on Nb2 cellsQ40988212
Bioproduction of human enzymes in transgenic tobaccoQ41014188
Antibody production and engineering in plantsQ41014195
Containment of herbicide resistance through genetic engineering of the chloroplast genomeQ41096418
Protein expression using ubiquitin fusion and cleavageQ41238701
Proteolysis in plants: mechanisms and functionsQ41288801
Gene silencing: cosuppression at a distanceQ41651135
Pioneering recombinant growth hormone manufacturing: pounds produced per mile of heightQ43720995
Equivalent potency and pharmacokinetics of recombinant human growth hormones with or without an N-terminal methionineQ46828920
Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potatoQ47614578
Protein disulfide isomerase as a regulator of chloroplast translational activationQ48041388
Expression, secretion and folding of human growth hormone in Escherichia coli. Purification and characterizationQ68894850
Translation of psbA mRNA is regulated by light via the 5'-untranslated region in tobacco plastidsQ72874185
Recombinant human growth hormone: old and novel usesQ74830376
A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpesQ77683899
Technical Advance: Stable chloroplast transformation in potato: use of green fluorescent protein as a plastid markerQ78216302
Stable expression of a biodegradable protein-based polymer in tobacco chloroplastsQ91514537
P433issue3
P304page(s)333-338
P577publication date2000-03-01
P1433published inNature BiotechnologyQ1893837
P1476titleHigh-yield production of a human therapeutic protein in tobacco chloroplasts
P478volume18

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