p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis

scientific article published on June 1999

p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1040304525
P356DOI10.1038/SJ.ONC.1202696
P698PubMed publication ID10380885
P5875ResearchGate publication ID12918075

P2093author name stringLiu C
Fan Y
Adamson ED
Huang RP
Mercola D
de Belle I
P2860cites workX-linked IAP is a direct inhibitor of cell-death proteasesQ24318710
Disruption of epithelial cell-matrix interactions induces apoptosisQ24673611
p53, the cellular gatekeeper for growth and divisionQ27860990
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Cleavage of focal adhesion kinase by caspases during apoptosisQ28610850
Suppression of human colorectal carcinoma cell growth by wild-type p53Q29618318
A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarizationQ29618351
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domainQ29620169
Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinaseQ30442141
Inhibition of pp125FAK in cultured fibroblasts results in apoptosisQ30442183
Control of adhesion-dependent cell survival by focal adhesion kinaseQ30442196
The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expressionQ34197959
p53 functions as a cell cycle control protein in osteosarcomasQ34254691
E1a induces the expression of epithelial characteristicsQ36382960
Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6.Q36555870
Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta 1.Q37271247
The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineageQ38322297
The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1.Q38328584
Role of Egr-1 gene expression in B cell receptor-induced apoptosis in an immature B cell lymphomaQ38342103
EGR-1 induction is required for maximal radiosensitivity in A375-C6 melanoma cellsQ38351455
Modifications of p53 Protein and Accumulation of p21 and gadd45 mRNA in TGF-β1 Growth Inhibited CellsQ38557138
Radiation induction of immediate early genes: effectors of the radiation-stress response.Q40701268
Tumor-suppressor p53 and the cell cycleQ40886481
Egr-1 inhibits apoptosis during the UV response: correlation of cell survival with Egr-1 phosphorylationQ40961191
Reversal of malignancy by the adenovirus E1a geneQ41002704
SAGE transcript profiles for p53-dependent growth regulationQ41092725
Early growth response-1-dependent apoptosis is mediated by p53.Q41094563
Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene.Q41101036
Fibronectin suppresses apoptosis in normal human melanocytes through an integrin-dependent mechanismQ41131825
C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposureQ41258141
Essential role for p53-mediated transcription in E1A-induced apoptosisQ41302308
Functions of the p53 Protein in Growth Regulation and Tumor SuppressionQ41506167
UV activates growth factor receptors via reactive oxygen intermediatesQ42772075
Protein kinase C-zeta reverts v-raf transformation of NIH-3T3 cellsQ42811974
V-sis induces Egr-1 expression by a pathway mediated by c-Ha-RasQ42832188
Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cellsQ45125758
Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis.Q47827995
Inhibition of cell growth by transforming growth factor beta 1 is associated with p53-independent induction of p21 in gastric carcinoma cells.Q55006218
Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formationQ73486628
Ionizing radiation-inducible apoptosis in the absence of p53 linked to transcription factor EGR-1Q73959969
Suppression of human fibrosarcoma cell growth by transcription factor, Egr-1, involves down-regulation of Bcl-2Q77132887
Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cellsQ77500551
P433issue24
P407language of work or nameEnglishQ1860
P304page(s)3633-3642
P577publication date1999-06-01
P1433published inOncogeneQ1568657
P1476titlep53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis
P478volume18

Reverse relations

cites work (P2860)
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