scholarly article | Q13442814 |
P2093 | author name string | A Cao | |
R Zhang | |||
S Germana | |||
L A Turka | |||
M Y Fan | |||
N A Zwang | |||
W D Hastings | |||
P2860 | cites work | Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells | Q24645614 |
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome | Q24679039 | ||
Control of regulatory T cell development by the transcription factor Foxp3 | Q27860489 | ||
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice | Q28215433 | ||
Signaling by the phosphoinositide 3-kinase family in immune cells | Q28283677 | ||
Modulation of interleukin-6 by beta2-adrenoceptor in endotoxin-stimulated renal macrophage cells | Q28372026 | ||
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells | Q29618394 | ||
PI3Kγ kinase activity is required for optimal T-cell activation and differentiation. | Q42180812 | ||
Rules of engagement: distinct functions for the four class I PI3K catalytic isoforms in immunity | Q42413337 | ||
Peritoneal macrophage priming in cirrhosis is related to ERK phosphorylation and IL-6 secretion | Q42476081 | ||
Role of MAP kinases and PI3K-Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients | Q42519528 | ||
MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells | Q43241045 | ||
Differential regulation of human IL-7 receptor alpha expression by IL-7 and TCR signaling | Q46662931 | ||
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. | Q46674143 | ||
ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis | Q48026306 | ||
The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro. | Q48692254 | ||
Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation. | Q51981008 | ||
Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. | Q52041208 | ||
MEK inhibition, alone or in combination with BRAF inhibition, affects multiple functions of isolated normal human lymphocytes and dendritic cells. | Q54357319 | ||
Assessing the efficacy of targeting the phosphatidylinositol 3-kinase/AKT/mTOR signaling pathway in endometrial cancer. | Q54375657 | ||
Cyclic AMP suppresses TGF-β-mediated adaptive Tregs differentiation through inhibiting the activation of ERK and JNK. | Q54407744 | ||
Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function. | Q54483264 | ||
Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells | Q56901500 | ||
PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis | Q57006266 | ||
Regulatory T cells in kidney allograft infiltrates correlate with initial inflammation and graft function | Q82632541 | ||
Rapid assessment of in vitro expanded human regulatory T cell function | Q84586428 | ||
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice | Q29622850 | ||
Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network. | Q30497351 | ||
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. | Q33889530 | ||
A Disquisition on Suppressor T Cells | Q34051239 | ||
Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I | Q34273324 | ||
Selective inhibition of regulatory T cells by targeting the PI3K-Akt pathway. | Q34458364 | ||
The MAPK pathway across different malignancies: a new perspective | Q34459097 | ||
Phosphoinositide 3-kinase in immunological systems | Q34555099 | ||
A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy. | Q34634834 | ||
Multiple control of interleukin-8 gene expression | Q34648084 | ||
Constitutive activation of MEK1 promotes Treg cell instability in vivo | Q34737755 | ||
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells | Q34927437 | ||
Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability | Q34979483 | ||
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses. | Q34979730 | ||
Foxp3-mediated inhibition of Akt inhibits Glut1 (glucose transporter 1) expression in human T regulatory cells | Q35005900 | ||
The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation | Q35133782 | ||
X-linked lymphoreticular disease in the scurfy (sf) mutant mouse | Q35831357 | ||
Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival | Q35849523 | ||
Polar opposites: Erk direction of CD4 T cell subsets | Q36084223 | ||
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. | Q36693820 | ||
MEK inhibitors selectively suppress alloreactivity and graft-versus-host disease in a memory stage-dependent manner | Q36907824 | ||
PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer | Q37025086 | ||
PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk | Q37133085 | ||
Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response | Q37376774 | ||
The Role of the PI3K Signaling Pathway in CD4(+) T Cell Differentiation and Function | Q38035848 | ||
T-cell energy metabolism as a controller of cell fate in transplantation | Q38309276 | ||
Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors | Q38406496 | ||
Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase | Q38893052 | ||
Combination treatment with perifosine and MEK-162 demonstrates synergism against lung cancer cells in vitro and in vivo | Q38907955 | ||
JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer | Q39226686 | ||
T cell-signaling network analysis reveals distinct differences between CD28 and CD2 costimulation responses in various subsets and in the MAPK pathway between resting and activated regulatory T cells | Q39695617 | ||
Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4. | Q39758257 | ||
Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation. | Q40083199 | ||
PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl cAMP. | Q40594170 | ||
Regulation of Raf-Akt Cross-talk | Q40727585 | ||
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration | Q40900789 | ||
PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans | Q41367429 | ||
p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system | Q41732350 | ||
Does the PI3K pathway promote or antagonize regulatory T cell development and function? | Q41864874 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2624-2638 | |
P577 | publication date | 2016-03-28 | |
P1433 | published in | American Journal of Transplantation | Q4744273 |
P1476 | title | Selective Sparing of Human Tregs by Pharmacologic Inhibitors of the Phosphatidylinositol 3-Kinase and MEK Pathways | |
P478 | volume | 16 |
Q89777371 | Emerging role of BCR signaling inhibitors in immunomodulation of chronic lymphocytic leukemia |
Q48097984 | Evidence of the immunomodulatory role of dual PI3K/mTOR inhibitors in transplantation: an experimental study in mice. |
Q92758418 | Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor |
Q40213848 | PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target. |
Q39441315 | Targeted Therapy and Immunosuppression in the Tumor Microenvironment |
Q38942832 | Treg-Centric View of Immunosuppressive Drugs in Transplantation: A Balancing Act. |
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