Chronic nicotine treatment up-regulates human alpha3 beta2 but not alpha3 beta4 acetylcholine receptors stably transfected in human embryonic kidney cells

scientific article published on October 1998

Chronic nicotine treatment up-regulates human alpha3 beta2 but not alpha3 beta4 acetylcholine receptors stably transfected in human embryonic kidney cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.273.44.28721
P698PubMed publication ID9786868
P5875ResearchGate publication ID13499236

P2093author name stringWang F
Cooper J
Lindstrom J
Kuryatov A
Nelson ME
Olale F
Keyser K
P433issue44
P407language of work or nameEnglishQ1860
P921main subjectnicotineQ12144
P304page(s)28721-28732
P577publication date1998-10-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleChronic nicotine treatment up-regulates human alpha3 beta2 but not alpha3 beta4 acetylcholine receptors stably transfected in human embryonic kidney cells
P478volume273

Reverse relations

cites work (P2860)
Q36323450A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit
Q36077726AT-1001 Is a Partial Agonist with High Affinity and Selectivity at Human and Rat α3β4 Nicotinic Cholinergic Receptors
Q34458445Acetylcholine Receptor (AChR) α5 Subunit Variant Associated with Risk for Nicotine Dependence and Lung Cancer Reduces (α4β2)2α5 AChR Function
Q48892669Acetylcholine receptor extracellular domain determines sensitivity to nicotine-induced inactivation
Q33862589Acetylcholine receptors and myasthenia
Q39061997Acute activation, desensitization and smoldering activation of human acetylcholine receptors
Q35978097Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors.
Q40724473Alcohol modulation of neuronal nicotinic acetylcholine receptors is alpha subunit dependent
Q34278091Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors
Q35662305An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors
Q28582276An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine
Q33598797Antigenic structure of the human muscle nicotinic acetylcholine receptor main immunogenic region
Q44699098Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons.
Q34340033Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes.
Q42173324Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation
Q37247103Cellular events in nicotine addiction
Q34498016Cellular mechanisms of nicotine addiction
Q40687661Changes in conformation and subcellular distribution of alpha4beta2 nicotinic acetylcholine receptors revealed by chronic nicotine treatment and expression of subunit chimeras.
Q39981430Characterization of ganglionic acetylcholine receptor autoantibodies
Q33922581Characterization of the recombinant human neuronal nicotinic acetylcholine receptors alpha3beta2 and alpha4beta2 stably expressed in HEK293 cells
Q28486758Chemical chaperones exceed the chaperone effects of RIC-3 in promoting assembly of functional α7 AChRs
Q36519472Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice
Q42556634Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation
Q35859988Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells
Q46056361Connections of nicotine to cancer
Q34498025Cue dependency of nicotine self-administration and smoking.
Q37148158Cyclic AMP-dependent protein kinase A and protein kinase C phosphorylate alpha4beta2 nicotinic receptor subunits at distinct stages of receptor formation and maturation
Q46587041Deletion of the beta 2 nicotinic acetylcholine receptor subunit alters development of tolerance to nicotine and eliminates receptor upregulation
Q40360827Desensitization of neuronal nicotinic receptors of human neuroblastoma SH-SY5Y cells during short or long exposure to nicotine
Q44590890Differential Regulation of Nicotinic Acetylcholine Receptors in PC12 Cells by Nicotine and Nerve Growth Factor
Q28345770Differential effects of chronic drug treatment on alpha3* and alpha7 nicotinic receptor binding sites, in hippocampal neurones and SH-SY5Y cells
Q64954374Discovery of an intrasubunit nicotinic acetylcholine receptor binding site for the positive allosteric modulator Br-PBTC.
Q52169026Effects of cholinergic deafferentation upon the expression of the alpha2 subunit of the nicotinic acetylcholine receptors in the chick lateral spiriform nucleus.
Q43263931Effects of chronic drug treatments on increases in intracellular calcium mediated by nicotinic acetylcholine receptors in SH-SY5Y cells
Q38015348Emerging Pharmacological Properties of Cholinergic Synaptic Transmission: Comparison between Mammalian and Insect Synaptic and Extrasynaptic Nicotinic Receptors
Q34458500Expression of Functional Human α6β2β3* Acetylcholine Receptors in Xenopus laevis Oocytes Achieved through Subunit Chimeras and Concatamers
Q24673473Formation of functional alpha3beta4alpha5 human neuronal nicotinic receptors in Xenopus oocytes: a reporter mutation approach
Q36445225Functional properties of human nicotinic AChRs expressed by IMR-32 neuroblastoma cells resemble those of alpha3beta4 AChRs expressed in permanently transfected HEK cells
Q41891669Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption.
Q50722158Human alpha6 AChR subtypes: subunit composition, assembly, and pharmacological responses.
Q48439102Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers.
Q37003060Identifying the lipid-protein interface of the alpha4beta2 neuronal nicotinic acetylcholine receptor: hydrophobic photolabeling studies with 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine.
Q27010347Inside-out neuropharmacology of nicotinic drugs
Q35694111Involvement of neuronal β2 subunit-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal: implications for pharmacotherapies
Q43662839Long-lasting enhancement of glutamatergic synaptic transmission by acetylcholine contrasts with response adaptation after exposure to low-level nicotine.
Q40354072Long-term exposure to the new nicotinic antagonist 1,2-bisN-cytisinylethane upregulates nicotinic receptor subtypes of SH-SY5Y human neuroblastoma cells
Q27658065Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity
Q40401402Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors
Q90603824More than Smoke and Patches: The Quest for Pharmacotherapies to Treat Tobacco Use Disorder
Q36890894Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity.
Q37395079Myasthenia gravis and the tops and bottoms of AChRs: antigenic structure of the MIR and specific immunosuppression of EAMG using AChR cytoplasmic domains
Q35649128Myasthenogenicity of the main immunogenic region and endogenous muscle nicotinic acetylcholine receptors
Q36137598Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions
Q37577758Nicotine and behavioral sensitization
Q37413060Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.
Q46979959Nicotine regulates multiple synaptic proteins by inhibiting proteasomal activity.
Q30404700Nicotine withdrawal
Q35777580Nicotine-induced upregulation of native neuronal nicotinic receptors is caused by multiple mechanisms
Q37525085Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction
Q47939175Nicotine-modulated subunit stoichiometry affects stability and trafficking of α3β4 nicotinic receptor.
Q30049245Nicotinic Acetylcholine Receptors of Muscles and Nerves
Q31909911Nicotinic acetylcholine receptor subunit proteins alpha7 and beta4 decrease in the superior cervical ganglion after axotomy
Q73247387Nicotinic acetylcholine receptors in neonatal motoneurons are regulated by axotomy: an electrophysiological and immunohistochemical study in human bcl-2 transgenic mice
Q26782271Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug use
Q48133939Nicotinic alpha5 subunit deletion locally reduces high-affinity agonist activation without altering nicotinic receptor numbers
Q46523776Nicotinic receptor activation contrasts pathophysiological bursting and neurodegeneration evoked by glutamate uptake block on rat hypoglossal motoneurons.
Q48587669Nicotinic receptor blockade decreases fos immunoreactivity within orexin/hypocretin-expressing neurons of nicotine-exposed rats.
Q28580107Nicotinic receptor subunit alpha5 modifies assembly, up-regulation, and response to pro-inflammatory cytokines
Q47602237Pharmacological Chaperones: Beyond Conformational Disorders
Q27001695Pharmacological chaperoning: a primer on mechanism and pharmacology
Q37478040Postsynaptic scaffolds for nicotinic receptors on neurons
Q43513045Prenatal nicotine exposure is associated with an increase in [125I]epibatidine binding in discrete cortical regions in rats
Q52166783Prenatal nicotine exposure: effects on locomotor activity and central [125I]alpha-BT binding in rats.
Q33843639Prenatal nicotine increases pulmonary alpha7 nicotinic receptor expression and alters fetal lung development in monkeys
Q36237673Probing the Allosteric Role of the α5 Subunit of α3β4α5 Nicotinic Acetylcholine Receptors by Functionally Selective Modulators and Ligands
Q33954007Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors
Q34668336RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulation
Q40003906Role of acetylcholine receptors in proliferation and differentiation of P19 embryonal carcinoma cells
Q35831006Role of α7- and β4-containing nicotinic acetylcholine receptors in the affective and somatic aspects of nicotine withdrawal: studies in knockout mice
Q34571365SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile
Q40961203Single channel properties of human alpha3 AChRs: impact of beta2, beta4 and alpha5 subunits
Q77223769Spatiotemporal patterns of activity in an intact mammalian network with single-cell resolution: optical studies of nicotinic activity in an enteric plexus
Q44618363Subtype-Selective Up-Regulation by Chronic Nicotine of High-Affinity Nicotinic Receptors in Rat Brain Demonstrated by Receptor Autoradiography
Q44801097Synergistic control of keratinocyte adhesion through muscarinic and nicotinic acetylcholine receptor subtypes
Q37593350Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors
Q46931502The alpha4beta2alpha5 nicotinic cholinergic receptor in rat brain is resistant to up-regulation by nicotine in vivo
Q31878432The effect of nicotine and haloperidol co-treatment on nicotinic receptor levels in the rat brain
Q44333468The opioid antagonist naltrexone inhibits activity and alters expression of alpha7 and alpha4beta2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs
Q35058426The ubiquitin-proteasome system regulates the stability of neuronal nicotinic acetylcholine receptors
Q40846948The unusual nature of epibatidine responses at the alpha4beta2 nicotinic acetylcholine receptor
Q28507709UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors
Q40386985Ubiquilin-1 regulates nicotine-induced up-regulation of neuronal nicotinic acetylcholine receptors
Q52279000[(3)H]Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day.

Search more.